McMillian Research – COVID-19 Research Project


COVID-19 Research Project

The aim of this research project is to understand the immune dysregulation in COVID-19 which is the primary cause of lung damage, leading to death, in order to change the course of the pandemic. The hypothesis is that autoimmunity to ACE-2 (the viral entry receptor) is triggered when elevated levels of serum ACE-2 bind to viral spike proteins. Research at Johns Hopkins University recently confirmed a part of this hypothesis by identifying IgM autoantibodies to ACE-2 in the serum of severe cases. This research project is expected to focus on a comprehensive search for autoantibodies to ACE-2 in people with COVID-19.

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