Boys

Vaccine News – VaxXed Stories: Tesha Muhammad in Oakland, CA

VaxXed Stories: Nathan in Columbus, OH

VaxXed Stories: Sisters in Columbus, OH

VaxXed Stories: Anonymous Baptist Pastor in Columbus, OH

VaxXed Stories: The Robinson Family in Columbus, OH

VaxXed Stories: Anonymous Correctional Facuility Healthcare Worker in Charleston, WV

Minister Christopher in Oakland, CA

Question About Eugenics in Oakland, CA

Question About African American Boys in Oakland, CA

Question About Constitutional Right to Education in Oakland, CA

VaxXed Stories: Tesha Muhammad in Oakland, CA

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Steve Quayle and Pastor David Lankford – The Rapture

ONE FOR ISRAEL Ministry – Jewish Johnathan Ben-David forgave his killer and you would not believe why!!!

How to accept Jesus Christ as your personal Saviour

Testimony by Phil Robertson from Duck Dynasty

1 Corinthians 15 Authorized (King James) Version (AKJV)

1 Moreover, brethren, I declare unto you the gospel which I preached unto you, which also ye have received, and wherein ye stand;
2 by which also ye are saved, if ye keep in memory what I preached unto you, unless ye have believed in vain.
3 For I delivered unto you first of all that which I also received, how that Christ died for our sins according to the scriptures;
4 and that he was buried, and that he rose again the third day according to the scriptures:

1 Corinthians 12

1 Now concerning spiritual gifts, brethren, I would not have you ignorant.
2 Ye know that ye were Gentiles, carried away unto these dumb idols, even as ye were led.
3 Wherefore I give you to understand, that no man speaking by the Spirit of God calleth Jesus accursed: and that no man can say that Jesus is the Lord, but by the Holy Ghost.

4 Now there are diversities of gifts, but the same Spirit.
5 And there are differences of administrations, but the same Lord.
6 And there are diversities of operations, but it is the same God which worketh all in all.
7 But the manifestation of the Spirit is given to every man to profit withal.
8 For to one is given by the Spirit the word of wisdom; to another the word of knowledge by the same Spirit;
9 to another faith by the same Spirit; to another the gifts of healing by the same Spirit;
10 to another the working of miracles; to another prophecy; to another discerning of spirits; to another divers kinds of tongues; to another the interpretation of tongues:
11 but all these worketh that one and the selfsame Spirit, dividing to every man severally as he will.

12 For as the body is one, and hath many members, and all the members of that one body, being many, are one body: so also is Christ.
13 For by one Spirit are we all baptized into one body, whether we be Jews or Gentiles, whether we be bond or free; and have been all made to drink into one Spirit.

Hebrews 6 Authorized (King James) Version (AKJV)

1 Therefore leaving the principles of the doctrine of Christ, let us go on unto perfection; not laying again the foundation of repentance from dead works, and of faith toward God,
2 of the doctrine of baptisms, and of laying on of hands, and of resurrection of the dead, and of eternal judgment.
3 And this will we do, if God permit.
4 For it is impossible for those who were once enlightened, and have tasted of the heavenly gift, and were made partakers of the Holy Ghost,
5 and have tasted the good word of God, and the powers of the world to come,
6 if they shall fall away, to renew them again unto repentance; seeing they crucify to themselves the Son of God afresh, and put him to an open shame.
7 For the earth which drinketh in the rain that cometh oft upon it, and bringeth forth herbs meet for them by whom it is dressed, receiveth blessing from God:
8 but that which beareth thorns and briers is rejected, and is nigh unto cursing; whose end is to be burned.

Isaiah 53 – Old testament Prophecy about Jesus

1 Who hath believed our report? and to whom is the arm of the Lord revealed?
2 For he shall grow up before him as a tender plant,and as a root out of a dry ground:he hath no form nor comeliness;and when we shall see him,there is no beauty that we should desire him.
3 He is despised and rejected of men;a man of sorrows, and acquainted with grief:and we hid as it were our faces from him;he was despised, and we esteemed him not.
4 Surely he hath borne our griefs,and carried our sorrows:yet we did esteem him stricken,smitten of God, and afflicted.
5 But he was wounded for our transgressions,he was bruised for our iniquities:the chastisement of our peace was upon him;and with his stripes we are healed.
6 All we like sheep have gone astray;we have turned every one to his own way;and the Lord hath laid on him the iniquity of us all.
7 He was oppressed, and he was afflicted,yet he opened not his mouth:he is brought as a lamb to the slaughter,and as a sheep before her shearers is dumb,so he openeth not his mouth.
8 He was taken from prison and from judgment:and who shall declare his generation? for he was cut off out of the land of the living:for the transgression of my people was he stricken.
9 And he made his grave with the wicked,and with the rich in his death;because he had done no violence,neither was any deceit in his mouth.
10 Yet it pleased the Lord to bruise him;he hath put him to grief:when thou shalt make his soul an offering for sin,he shall see his seed, he shall prolong his days,and the pleasure of the Lord shall prosper in his hand.
11 He shall see of the travail of his soul, and shall be satisfied:by his knowledge shall my righteous servant justify many;for he shall bear their iniquities.
12 Therefore will I divide him a portion with the great,and he shall divide the spoil with the strong;because he hath poured out his soul unto death:and he was numbered with the transgressors;and he bare the sin of many,and made intercession for the transgressors.

The Only Sin That Leads To Hell – Kenneth E Hagin

Vaccine News – VAXXED TV – Stories in northern Auckland & Study – Characterisation of poxviruses from sporadic human infections

Europe’s journal on infectious disease surveillance, epidemiology, prevention and control – 2013

Study – Case of vaccine-associated measles five weeks post-immunisation, British Columbia, Canada, October 2013

M Murti – 1, M Krajden – 2, M Petric – 2, J Hiebert – 3, F Hemming – 1, B Hefford – 4, M Bigham – 1, P Van Buynder – 1

Author Affiliations:
1 Fraser Health Authority, Surrey, British Columbia, Canada
2 Public Health Microbiology and Reference Laboratory British Columbia Centre for Disease Control, Vancouver, British Columbia, Canada
3 National Microbiology Laboratory, Public Health Agency of Canada, Winnipeg, Manitoba, Canada
4 1-1400 George St., White Rock, British Columbia, Canada

Case report
We describe a case of vaccine-associated measles in a two-year-old patient from British Columbia, Canada, in October 2013, who received her first dose of measles-containing vaccine 37 days prior to onset of prodromal symptoms. Identification of this delayed vaccine-associated case occurred in the context of an outbreak investigation of a measles cluster.
In this report we describe a case of measles-mumps-rubella (MMR) vaccine-associated measles illness that was positive by both PCR and IgM, five weeks after administration of the MMR vaccine. Based on our literature review, we believe this is the first such case report which has implications for both public health follow-up of measles cases and vaccine safety surveillance.
Between 29 August and 2 September 2013, three unlinked persons from across the Fraser Valley, British Columbia, Canada, presented with rash illness consistent with clinical measles [1]. Based on the outbreak investigation by the local health authority, none of the three cases had an identified exposure to a measles case or travel history outside of Canada during the incubation period, and a source case was never identified. All three cases had the same measles genotype B3 sequence type (MVs/British Columbia.CAN/34.13, MeaNS id 39928, GenBank accession numbers KF704002 and KF704001). Measles genotype B3 is endemic in the World Health Organization’s African and Eastern Mediterranean regions [2]. Two additional cases of measles due to secondary transmission from one of the above cases were identified in British Columbia in the third week of September.

US National Library of Medicine
National Institutes of Health – 1987

Study – Characterisation of poxviruses from sporadic human infections.

Authors
Carra L – 1, Dumbell KR.
Author information
Department of Medical Microbiology, University of Cape Town.

Abstract
An orthopoxvirus was isolated from the vesicular rash of a man in Natal who died in coma and who had not been vaccinated. Analysis of the viral DNA showed that it was a vaccinia virus, more closely related to the virus of South African smallpox vaccine than to other vaccinia viruses. DNA analysis also showed that an orthopoxvirus isolated from a sporadic case of severe pustular rash in Nigeria was a vaccinia virus closely related to the smallpox vaccine virus used there. Minor biological differences between the viruses isolated and the corresponding vaccine strains suggested that some natural transmission of the virus had occurred, but the results of DNA analysis implied that they originated from the use of smallpox vaccine. No similar cases have been detected since smallpox vaccination was discontinued.

US National Library of Medicine
National Institutes of Health – 1989

Study – Acute maternal anterior poliomyelitis in a non-endemic zone

Derenne F – 1, Vanderheyden JE, Bain H, Jocquet P, Jacquy J, Yane F, Druyts-Voets E, Lamy ME, Vanhaeverbeek M.
Author information
Service de Médecine Interne, C.H.U. André Vésale, U.L.B., Montigny-le-Tilleul.

Abstract
The authors report the case of a 26 year old woman with acute anterior poliomyelitis contracted during the vaccination of her baby. Despite having been herself vaccinated in infancy she was not protected against the poliovirus. The clinical interest of this uncommon case is a severe paralytic state with definitive paraplegia. The authors suggest serologic testing of patients born before 1967 especially if they are at risk of encountering the virus.

My own VAXXED/UNVAXXED study

Te Awamutu Vaxxed vs Unvaxxed

Interview in a hospital with Sarah Cox

More stories in Tauranga, New Zealand

Stories in Tauranga, New Zealand

My two boys are injured

Meeting Andre and Kazia

Vaccinated vs unvaccinated in Northern Auckland

More stories in Northern Auckland

Stories in northern Auckland

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ONE FOR ISRAEL Ministry – Jewish Johnathan Ben-David forgave his killer and you would not believe why!!!

How to accept Jesus Christ as your personal Saviour

Testimony by Phil Robertson from Duck Dynasty

1 Corinthians 15 Authorized (King James) Version (AKJV)
1 Moreover, brethren, I declare unto you the gospel which I preached unto you, which also ye have received, and wherein ye stand;
2 by which also ye are saved, if ye keep in memory what I preached unto you, unless ye have believed in vain.
3 For I delivered unto you first of all that which I also received, how that Christ died for our sins according to the scriptures;
4 and that he was buried, and that he rose again the third day according to the scriptures:

Hebrews 6 Authorized (King James) Version (AKJV)
1 Therefore leaving the principles of the doctrine of Christ, let us go on unto perfection; not laying again the foundation of repentance from dead works, and of faith toward God,
2 of the doctrine of baptisms, and of laying on of hands, and of resurrection of the dead, and of eternal judgment.
3 And this will we do, if God permit.
4 For it is impossible for those who were once enlightened, and have tasted of the heavenly gift, and were made partakers of the Holy Ghost,
5 and have tasted the good word of God, and the powers of the world to come,
6 if they shall fall away, to renew them again unto repentance; seeing they crucify to themselves the Son of God afresh, and put him to an open shame.
7 For the earth which drinketh in the rain that cometh oft upon it, and bringeth forth herbs meet for them by whom it is dressed, receiveth blessing from God:
8 but that which beareth thorns and briers is rejected, and is nigh unto cursing; whose end is to be burned.

Isaiah 53 – Old testament Prophecy about Jesus

The Only Sin That Leads To Hell – Kenneth E Hagin

Vaccine News – VAXXED TV – Two of my three children are injured by vaccines & Study – Correlations Between Gene Expression and Mercury Levels in Blood of Boys With and Without Autism

US National Library of Medicine
National Institutes of Health – Jan 2011

Study – Correlations Between Gene Expression and Mercury Levels in Blood of Boys With and Without Autism

Boryana Stamova,corresponding author – 1,9,10
Peter G. Green,2
Yingfang Tian,1,9,10
Irva Hertz-Picciotto,3,9,10
Isaac N. Pessah,4,9,10
Robin Hansen,5,9,10
Xiaowei Yang,3
Jennifer Teng,1
Jeffrey P. Gregg,6,9,10
Paul Ashwood,7,9,10
Judy Van de Water,8,9,10
and Frank R. Sharp1,9,10
1 – Department of Neurology, University of California at Davis Medical Center, Sacramento, CA 95817 USA
2 – Department of Civil and Environmental Engineering, University of California at Davis, Sacramento, CA USA
3 – Department of Public Health Sciences, University of California at Davis Medical Center, Sacramento, CA USA
4 – Department of VM: Molecular Biosciences, University of California at Davis Medical Center, Sacramento, CA USA
5 – Department of Pediatrics, University of California at Davis Medical Center, Sacramento, CA USA
6 – Department of Pathology, University of California at Davis Medical Center, Sacramento, CA USA
7 – Department of Medical Microbiology and Immunology, University of California at Davis Medical Center, Sacramento, CA USA
8 – Division of Rheumatology, Allergy and Clinical Immunology, University of California at Davis Medical Center, Sacramento, CA USA
9 – The MIND Institute, University of California at Davis Medical Center, 2805 50th Street, Room 2434, Sacramento, CA USA
10 – UC Davis Center for Children’s Environmental Health and Disease Prevention, Sacramento, CA USA

Abstract
Gene expression in blood was correlated with mercury levels in blood of 2- to 5-year-old boys with autism (AU) compared to age-matched typically developing (TD) control boys. This was done to address the possibility that the two groups might metabolize toxicants, such as mercury, differently. RNA was isolated from blood and gene expression assessed on whole genome Affymetrix Human U133 expression microarrays. Mercury levels were measured using an inductively coupled plasma mass spectrometer. Analysis of covariance (ANCOVA) was performed and partial correlations between gene expression and mercury levels were calculated, after correcting for age and batch effects. To reduce false positives, only genes shared by the ANCOVA models were analyzed. Of the 26 genes that correlated with mercury levels in both AU and TD boys, 11 were significantly different between the groups (P(Diagnosis*Mercury) ≤ 0.05). The expression of a large number of genes (n = 316) correlated with mercury levels in TD but not in AU boys (P ≤ 0.05), the most represented biological functions being cell death and cell morphology. Expression of 189 genes correlated with mercury levels in AU but not in TD boys (P ≤ 0.05), the most represented biological functions being cell morphology, amino acid metabolism, and antigen presentation. These data and those in our companion study on correlation of gene expression and lead levels show that AU and TD children display different correlations between transcript levels and low levels of mercury and lead. These findings might suggest different genetic transcriptional programs associated with mercury in AU compared to TD children.

US National Library of Medicine
National Institutes of Health – Nov 1982

Study – Abnormal immune response to brain tissue antigen in the syndrome of autism

Abstract
Cell-mediated immune response to human myelin basic protein was studied by the macrophage migration inhibition factor test in 17 autistic patients and a control group of 11 patients suffering from other mental diseases included in the differential diagnosis of the syndrome of autism. Of the 17 autistic patients, 13 demonstrated inhibition of macrophage migration, whereas none of the nonautistic patients showed such a response. The results indicate the existence of a cell-mediated immune response to brain tissue in the syndrome of autism.

US National Library of Medicine
National Institutes of Health – Apr 2000

Study – Detection and sequencing of measles virus from peripheral mononuclear cells from patients with inflammatory bowel disease and autism.

Kawashima H, Mori T, Kashiwagi Y, Takekuma K, Hoshika A, Wakefield A.
Author information
Department of Paediatrics, Tokyo Medical University, Japan.

Abstract
It has been reported that measles virus may be present in the intestine of patients with Crohn’s disease. Additionally, a new syndrome has been reported in children with autism who exhibited developmental regression and gastrointestinal symptoms (autistic enterocolitis), in some cases soon after MMR vaccine. It is not known whether the virus, if confirmed to be present in these patients, derives from either wild strains or vaccine strains. In order to characterize the strains that may be present, we have carried out the detection of measles genomic RNA in peripheral mononuclear cells (PBMC) in eight patients with Crohn’s disease, three patients with ulcerative colitis, and nine children with autistic enterocolitis. As controls, we examined healthy children and patients with SSPE, SLE, HIV-1 (a total of eight cases). RNA was purified from PBMC by Ficoll-paque, followed by reverse transcription using AMV; cDNAs were subjected to nested PCR for detection of specific regions of the hemagglutinin (H) and fusion (F) gene regions. Positive samples were sequenced directly, in nucleotides 8393-8676 (H region) or 5325-5465 (from noncoding F to coding F region). One of eight patients with Crohn disease, one of three patients with ulcerative colitis, and three of nine children with autism, were positive. Controls were all negative. The sequences obtained from the patients with Crohn’s disease shared the characteristics with wild-strain virus. The sequences obtained from the patients with ulcerative colitis and children with autism were consistent with being vaccine strains. The results were concordant with the exposure history of the patients. Persistence of measles virus was confirmed in PBMC in some patients with chronic intestinal inflammation.

VAXXED TV – I gave up being a nurse because of vaccines

My mother was never the same after vaccinations

Two of my three children are injured by vaccines

My vaccinated child gave my 4 month old baby chickenpox

The Lindermans – possible strong language!

Hep B vaccine made me sick

Joni Abbott interview

My niece is not vaccinated because of me

I am not having anymore vaccines

Vaccinated versus unvaxxed

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ONE FOR ISRAEL Ministry – Jewish Johnathan Ben-David forgave his killer and you would not believe why!!!

How to accept Jesus Christ as your personal Saviour

Testimony by Phil Robertson from Duck Dynasty

Isaiah 53 – Old testament Prophecy about Jesus

Vaccine News – VAXXED TV – I Wish We Would Have KNOWN! & Study – Failure to reach the goal of measles elimination. Apparent paradox of measles infections in immunized persons

US National Library of Medicine
National Institutes of Health – 22 Aug 1994

Study – Failure to reach the goal of measles elimination. Apparent paradox of measles infections in immunized persons.

Poland GA, Jacobson RM.
Author information
Department of Internal Medicine, Mayo Vaccine Research Group, Mayo Clinic and Foundation, Rochester, MN.

Abstract

BACKGROUND:
Measles is the most transmissible disease known to man. During the 1980s, the number of measles cases in the United States rose dramatically. Surprisingly, 20% to 40% of these cases occurred in persons who had been appropriately immunized against measles. In response, the United States adopted a two-dose universal measles immunization program. We critically examine the effect of vaccine failure in measles occurring in immunized persons.

METHODS:
We performed a computerized bibliographic literature search (National Library of Medicine) for all English-language articles dealing with measles outbreaks. We limited our search to reports of US and Canadian school-based outbreaks of measles, and we spoke with experts to get estimates of vaccine failure rates. In addition, we devised a hypothetical model of a school where measles immunization rates could be varied, vaccine failure rates could be calculated, and the percentage of measles cases occurring in immunized students could be determined.

RESULTS:
We found 18 reports of measles outbreaks in very highly immunized school populations where 71% to 99.8% of students were immunized against measles. Despite these high rates of immunization, 30% to 100% (mean, 77%) of all measles cases in these outbreaks occurred in previously immunized students. In our hypothetical school model, after more than 95% of schoolchildren are immunized against measles, the majority of measles cases occur in appropriately immunized children.

CONCLUSIONS:
The apparent paradox is that as measles immunization rates rise to high levels in a population, measles becomes a disease of immunized persons. Because of the failure rate of the vaccine and the unique transmissibility of the measles virus, the currently available measles vaccine, used in a single-dose strategy, is unlikely to completely eliminate measles. The long-term success of a two-dose strategy to eliminate measles remains to be determined.

Measles among vaccinated Quebec kids questioned
The Canadian Press Posted: Oct 20, 2011

An investigation into an outbreak in a high school in a town that was heavily hit by the virus found that about half of the cases were in teens who had received the recommended two doses of vaccine in childhood — in other words, teens whom authorities would have expected to have been protected from the measles virus.
It’s generally assumed that the measles vaccine, when given in a two-dose schedule in early childhood, should protect against measles infection about 99 per cent of the time. So the discovery that 52 of the 98 teens who caught measles were fully vaccinated came as a shock to the researchers who conducted the investigation.
“That’s the real question. How could that have happened?” said Dr. Gaston De Serres, an infectious diseases expert with Quebec’s public health agency and one of the authors of the study.
In an interview before the start of the conference, De Serres would not name the highly affected town or the high school in it.
But he suggested the discovery that as many of the cases were fully vaccinated as unvaccinated raises a serious question about whether the timing of the delivery of the first dose of measles vaccine is undermining the efficacy of the prevention program.

The vaccine can’t be given earlier, because of a phenomenon that helps babies survive infancy. Children are born without a fully developed immune system — it starts to build as babies become exposed to a variety of disease threats over their first few years.
In pregnancy and after birth, through breastfeeding, babies acquire antibodies from their mothers that tide them over until they can make their own. But that means if they are given the measles vaccine — which is made from weakened live viruses — too early, their mothers’ antibodies will kill the vaccine viruses, preventing protection from being induced.

US National Library of Medicine
National Institutes of Health – 2006

Study – Horizontal transmission of the Leningrad-3 live attenuated mumps vaccine virus

Abstract
Here we describe symptomatic transmission of the Leningrad-3 mumps vaccine virus from healthy vaccinees to previously vaccinated contacts. Throat swab and serum samples were taken from six symptomatic mumps cases and from 13 family contacts. Assessment of serum IgG and IgM anti-mumps virus antibodies and IgG avidity testing was performed using commercial test kits. Sera neutralizing antibodies were measured by plaque reduction neutralization assay using the L-3 vaccine mumps virus as the target. All six of the symptomatic mumps cases and three contact subjects tested positive for mumps by RT-PCR. The genomic sequences tested (F, SH and HN genes) of all nine of these samples were identical to the L-3 mumps vaccine strain. All 13 contacts were asymptomatic; however clear serological evidence of mumps infection was found in some of them. The likely epidemiological source of the transmitted L-3 mumps virus was children who were recently vaccinated at the schools attended by the six symptomatic mumps patients described here. The L-3 mumps vaccine virus can be shed and transmitted horizontally, even to subjects previously vaccinated with the same virus.

US National Library of Medicine
National Institutes of Health – 2014

Study – Difficulties in Eliminating Measles and Controlling Rubella and Mumps: A Cross-Sectional Study of a First Measles and Rubella Vaccination and a Second Measles, Mumps, and Rubella Vaccination

Zhifang Wang,1 Rui Yan,1 Hanqing He,1 Qian Li,1 Guohua Chen,2 Shengxu Yang,3 and Enfu Chen1,*
Martyn Kirk, Editor
1 – Zhejiang Provincial Center for Disease Control and Prevention, Hangzhou, Zhejiang Province, P. R. China
2 – Cixi City Center for Disease Control and Prevention, Cixi, Ningbo, P. R. China
3 – Sanmen County Center for Disease Control and Prevention, Sanmen, Taizhou, P. R. China

Abstract

Background
The reported coverage of the measles–rubella (MR) or measles–mumps–rubella (MMR) vaccine is greater than 99.0% in Zhejiang province. However, the incidence of measles, mumps, and rubella remains high. In this study, we assessed MMR seropositivity and disease distribution by age on the basis of the current vaccination program, wherein the first dose of MR is administered at 8 months and the second dose of MMR is administered at 18–24 months.

Methods
Cross-sectional serological surveys of MMR antibodies were conducted by collecting epidemiological data in Zhejiang province, China in 2011. In total, 1015 participants were randomly selected from two surveillance sites. Serum MMR-specific immunoglobulin G levels were tested by enzyme-linked immunosorbent assay. The geometric mean titers and seroprevalence with 95% confidence intervals (CIs) were calculated by age and gender. Proportions of different dose of vaccine by age by vaccine were also identified. Statistically significant differences between categories were assessed by the Chi-square test.

Results
Over 95% seroprevalence rates of measles were seen in all age groups except <7 months infants. Children aged 5–9 years were shown lower seropositivity rates of mumps while elder adolescences and young adults were presented lower rubella seroprevalence. Especially, rubella seropositivity was significantly lower in female adults than in male. Nine measles cases were unvaccinated or unknown vaccination history. Among them, 66.67% (6/9) patients were aged 20–29 years while 33.33% (3/9) were infants aged 8–12 months. In addition, 57.75% (648/1122) patients with mumps were children aged 5–9 years, and 50.54% (94/186) rubella cases were aged 15–39 years.

Conclusions
A timely two-dose MMR vaccination schedule is recommended, with the first dose at 8 months and the second dose at 18–24 months. An MR vaccination speed-up campaign may be necessary for elder adolescents and young adults, particularly young females.

I am injured by the flu shot

MMR vaccine injured me

My family is injured by vaccines

Hep B vaccine and Vit K made my baby sick

I Wish We Would Have KNOWN!
William and Rachael tell their story of their two boys who have suffered from vaccine injury in Ireland.
Interview recorded on May 5th, 2017 in The United Kingdom

I have finally woken up to the truth about vaccines

My 2 children have autism from vaccines

My son should never be vaccinated

Vaccines gave my son autism

My son caught measles from the MMR vaccine

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How to accept Jesus Christ as your personal Saviour

Testimony by Phil Robertson from Duck Dynasty

Vaccine News – Vaccines with human Cell Strains & VAXXED TV – Vaccines injured my family

US National Library of Medicine
National Institutes of Health – 2012

Study – Relative trends in hospitalizations and mortality among infants by the number of vaccine doses and age, based on the Vaccine Adverse Event Reporting System (VAERS), 1990-2010

Abstract
In this study, the Vaccine Adverse Event Reporting System (VAERS) database, 1990-2010, was investigated; cases that specified either hospitalization or death were identified among 38,801 reports of infants. Based on the types of vaccines reported, the actual number of vaccine doses administered, from 1 to 8, was summed for each case. Linear regression analysis of hospitalization rates as a function of (a) the number of reported vaccine doses and (b) patient age yielded a linear relationship with r(2) = 0.91 and r(2) = 0.95, respectively. The hospitalization rate increased linearly from 11.0% (107 of 969) for 2 doses to 23.5% (661 of 2817) for 8 doses and decreased linearly from 20.1% (154 of 765) for children aged <0.1 year to 10.7% (86 of 801) for children aged 0.9 year. The rate ratio (RR) of the mortality rate for 5-8 vaccine doses to 1-4 vaccine doses is 1.5 (95% confidence interval (CI), 1.4-1.7), indicating a statistically significant increase from 3.6% (95% CI, 3.2-3.9%) deaths associated with 1-4 vaccine doses to 5.5% (95% CI, 5.2-5.7%) associated with 5-8 vaccine doses. The male-to-female mortality RR was 1.4 (95% CI, 1.3-1.5). Our findings show a positive correlation between the number of vaccine doses administered and the percentage of hospitalizations and deaths. Since vaccines are given to millions of infants annually, it is imperative that health authorities have scientific data from synergistic toxicity studies on all combinations of vaccines that infants might receive. Finding ways to increase vaccine safety should be the highest priority.

Human Cell Strains in Vaccine Development

Vaccines Developed Using Human Cell Strains
The first licensed vaccine made with the use of a human cell strain was the adenovirus vaccine used by the military in the late 1960s. Later, other vaccines were developed in human cell strains, most notably the rubella vaccine developed by Stanley Plotkin, MD, at the Wistar Institute in Philadelphia.
In 1941, Australian ophthalmologist Norman Gregg first realized that congenital cataracts in babies were the result of their mothers being infected with rubella during pregnancy. Along with cataracts, it was eventually determined that congenital rubella syndrome (CRS) could also cause deafness, heart disease, encephalitis, mental retardation, and pneumonia, among many other conditions. At the height of a rubella epidemic that began in Europe and spread to the United States in the mid-1960s, Plotkin calculated that 1% of all births at Philadelphia General Hospital were affected by congenital rubella syndrome. In some cases, women who were infected with rubella while pregnant terminated their pregnancies due to the serious risks from CRS.
Following one such abortion, the fetus was sent to Plotkin at the laboratory he had devoted to rubella research. Testing the kidney of the fetus, Plotkin found and isolated the rubella virus. Separately, Leonard Hayflick (also working at the Wistar Institute at that time) developed a cell strain called WI-38 using lung cells from an aborted fetus. Hayflick found that many viruses, including rubella, grew well in the WI-38, and he showed that it proved to be free of contaminants and safe to use for human vaccines.
Plotkin grew the rubella virus he had isolated in WI-38 cells kept at 86°F (30°C), so that it eventually grew very poorly at normal body temperature. (He chose the low temperature approach following previous experiences with attenuating poliovirus.) After the virus had been grown through the cells 25 times at the lower temperature, it was no longer able to replicate enough to cause illness in a living person, but was still able to provoke a protective immune response. The rubella vaccine developed with WI-38 is still used throughout much of the world today as part of the combined MMR (measles, mumps, and rubella) vaccine.

The vaccines that contained these ingredients include:

Adenovirus
DTaP-IPV/Hib (Pentacel)
Hep A (Havrix)
Hep B (Engerix-B)
Hep A/Hep B (Twinrix)
MMR (MMR-II)
MMRV (ProQuad)
Rabies (Imovax)
Varicella (Varivax)
Zoster (Shingles – Zostavax)

Vaccine Excipient & Media Summary- 6 Jan 2017

Excipients Included in U.S. Vaccines, by Vaccine
In addition to weakened or killed disease antigens (viruses or bacteria), vaccines contain very small amounts of other
ingredients – excipients or media.
Some excipients are added to a vaccine for a specific purpose. These include:
Preservatives, to prevent contamination. For example, thimerosal.
Adjuvants, to help stimulate a stronger immune response. For example, aluminum salts.
Stabilizers, to keep the vaccine potent during transportation and storage. For example, sugars or gelatin.
Others are residual trace amounts of materials that were used during the manufacturing process and removed. These include:
Cell culture materials, used to grow the vaccine antigens. For example, egg protein, various culture media.
Inactivating ingredients, used to kill viruses or inactivate toxins. For example, formaldehyde.
Antibiotics, used to prevent contamination by bacteria. For example, neomycin.
The following table lists all components, other than antigens, shown in the manufacturers’ package insert (PI) for each vaccine.
Each of these PIs, which can be found on the FDA’s website (see below) contains a description of that vaccine’s manufacturing
process, including the amount and purpose of each substance. In most PIs, this information is found in Section 11: “Description.”

All information was extracted from manufacturers’ package inserts, current as of January 6, 2017.