Vaccine News – Temporal Association of Certain Neuropsychiatric Disorders Following Vaccination of Children and Adolescents: A Pilot Case–Control Study

“Pan Ran” Italian style: politicos who apparently pushed the forced vaccine law– Aniello Formisano, Elisa Mariano, Ludovico Vico and Salvatore Capone– rush to take refuge in cars to avoid confrontation with countless protesters.
Eyes on Italy… this is far from over.
When you sell your integrity and humanity to Big Pharma, there is a price to pay! Aniello Formisano, a member of the Democratic and Progressive Movement, is confronted by Italians who WILL NOT accept mandatory vaccination! Three deputies were also confronted, Elisa Mariano, Ludovico Vico and Salvatore Capone…They take refuge inside a car as they’re surrounded by citizens who are NOT GOING AWAY
#RevolutionForChoice #InformedConsent #EducateBeforeYouVaccinate #VAXXED #BigPharma #Italy #NotGoingAway

How much do Medical School students learn about vaccines? You might be surprised!
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#ItsYourFault Wake the He** Up!

Dr. Hotez is warning people about the devastation a measles outbreak in Texas could cause. Do his Zika warnings from last year make you still trust him? Part 2 of 2 (Ep79 is part 1).
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Thank you Deniece for sharing this HPV Plan:
HPV PLAN – ultimately to give it to babies. And why ? It’s too hard to give it to kids / teens, listen to Brian Hooker on this mini clip
5 min Clip on plans for the Gardisill HPV to BABIES 😢😭😡 right now 9-12 year olds are the Target. LISTEN to Brian Hooker PhD,PE bio Chemical Engineer & research Scientist. 750 micrograms Aluminum per shot

Makaylah’s Story ~
“On October 21, 2015 she received her required vaccinations to start school. After receiving those vaccines, she told her mom, “she just didn’t feel very well”.
gofund.me/makaykay
Soon, she began to trip and fall constantly. When playing with her siblings, she began to sit and rest during most of her play time due to loss of energy. She would use the walls or furniture for support to balance or walk and you could see her body having tremors. After taking her to many doctors and even after many tests, we are often told, “we don’t know.” We were also told she would need special help.
She cannot attend school alone. Her balance and stamina are not improving. Her motor functions, speech and food nutrients processing are in rapid decline.
On her last doctor visit in September 2016, they spoke of possibly incorporating a feeding tube.
Even after receiving the diagnosis of some form of “Ataxia”, some doctors still do not agree and believe the cause may be a toxin. Myself and the family believe it was caused by a toxin.
Corresponding with the multiple toxins she received in the form of vaccines on October 21, 2015.
I am Robert, her grandfather. I have seen her struggle with needing to use a walker and a wheel chair or just wondering why her body now reacts like it does.
She does not understand any of this because it was not long ago that she could run, play and just be a child. She often wakes up with seizures and trembling.
Her latest challenge is feeding herself. Please help us help Makayla in this medical mystery. We appreciate your contributions, donations and prayers for Makayla. May God Bless You Always for Sharing.”
gofund.me/makaykay
See this video also: https://www.facebook.com/RevolutionForChoice/videos/181771478897113/
#RevolutionForChoice #VAXXED #InformedConsent

Watch this! You won’t believe the way the Netherlands media treats a Chicken Pox outbreak compared to the U.S!
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The encephalitic scream induced by vaccines. Please parents, start TODAY acquiring the necessary knowledge to avoid the pitfalls created by an industry that calls the tremendous suffering depicted here NORMAL and then tells you to “wait it out”, while you watch your screaming baby suffer terribly: tinyurl.com/9Episodes
#RevolutionForChoice #InformedConsent #EducateBeforeYouVaccinate #VAXXED #Encephalitis #VaccineInjury

“Belief in immunization is a form of delusional insanity.”
Dr Herbert Shelton, USA

#VaxWithMe #VaxxedNationTour #VaxxedNation #Vaxxed #MedicalBilling #FetalDeath
Another incredible revelation coming from Marcella Piper-Terry of VaxTruth.Org. An employee of a medical billing company is sending records showing fetal death occurring following flu and TDaP vaccines when administered to pregnant women.

Dr. Suzanne Humphries testifies at the West Virginia Education Committee this morning (Saturday, March 18, 2017), “I was the doctor who used to guilt my patients into vaccines, until I learned what I know now.”
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Source Footage: http://sg001-harmony.sliq.net/00289/Harmony/en/PowerBrowser/PowerBrowserV2/20170318/-1/6461
Full length testimony coming soon!
#Vaxxed #PrayBig #RFKcommission #Truth #Science #VaxxedDoctors #MedicalProfessionals

After receiving a flu shot, this beautiful young girl suffered vaccine-induced paralysis, also known as Transverse Myeltis, one of many labels given to our modern-day “Polio”, which was never eradicated by vaccines and in fact, is many times directly caused by them.
What else aren’t you being told? Find out here, while this groundbreaking, 9-part docu-series is still free>>> tinyurl.com/9Episodes
Guillain-Barré Syndrome is another label given to this paralysis, very often caused by vaccines.
More info here: vactruth.com/2012/04/25/change-names-of-diseases
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✴️ Read all vaccine inserts: tinyurl.com/ReadTheVaccineInsert
#RevolutionForChoice #InformedConsent #EducateBeforeYouVaccinate #VAXXED #Polio #TransverseMyelitis #VaccineInjury

Dr. Brian Hooker – High Times at the CDC

12 Vaccini Obbligatori – 12 mandatory vaccines

Watch this brief clip of Erin Elizabeth’s (Erin from Health Nut News) presentation at last year’s TTAC Live event. She talks about the disproportionate number of deaths among alternative health practitioners in the past couple of years.
For information about this year’s TTAC LIVE 2017 symposium, please click here now: http://bit.ly/LE2017ttac

What happened in 1989 that warranted TWENTY-SIX more vaccines on the CDC schedule? HINT: In 1986, all vaccine manufacturers became immune to ALL financial liability from the destruction of life and health their vaccines cause! UNITE WITH US and learn all you can to protect your families: “Vaccines Revealed” 9-part docu-series, replaying now for free: tinyurl.com/9Episodes
2017: 50 DOSES OF 14 VACCINES BEFORE AGE 6
. . . . . .69 DOSES OF 16 VACCINES BY AGE 18
https://www.cdc.gov/vaccines/schedules/downloads/child/0-18yrs-child-combined-schedule.pdf
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#RevolutionForChoice #InformedConsent #EducateBeforeYouVaccinate #VAXXED #CDCVaccineSchedule

Over-vaccinating and the overdosing of pet vaccines has become a global issue. 5lb dogs are receiving the same dose of the rabies vaccine as 150lb Great Danes, and vets are now witnessing terrible side effects.

Ever wonder WHY we NEED a religious exemption from vaccines?
Are you aware that some vaccines are made from ABORTIONS?
Marcella Piper-Terry explains in detail how abortions are used in vaccine manufacturing and the implications of that.
Interview by Polly Tommey and camera by Joshua Coleman and Anu Vaidya with editing by Joshua Coleman.

#RFKCommission #Vaxxed

UFC Veteran Speaks Out Against Vaccines After Tragic Death of Son

By Brandon Turbeville
“This is unacceptable, I will fight for my son, this happened to the wrong family.” – Nick Catone
Former UFC fighter, Nick Catone, is making waves on social media. But while many fighters are drawing attention to themselves for attacking their opponents, Catone is gathering attention for another reason: his vocal criticism of vaccination.
For him, the issue is very personal since on May 12, his otherwise healthy 20-month-old son passed away in the middle of the night. While the family was initially perplexed as to how a healthy little boy could just simply die without warning, consultations with numerous doctors and even an autopsy yielded no results. Instead, the cause of Nicholas’ death was listed as “natural.”
Shortly after, however, Catone began hearing stories from other parents regarding their child’s adverse reactions to vaccines, ranging from seizures to autism and death. Catone began doing his own research and is now convinced that it was the vaccine that killed his son.

Toddler Wrongly Injected with Gardasil Vaccine Develops Rare Form of Leukaemia
by NATALIE AKOORIE
Stuff.co.nz
A Hamilton toddler who was mistakenly injected with a vaccine to prevent cervical cancer when he was just six weeks old has developed a rare form of leukaemia.
Chace Topperwien began chemotherapy for the M7 strand of acute myeloid leukaemia on his second birthday last month, but doctors cannot tell them whether the Gardasil vaccine he was injected with in May 2009 caused the cancer.
His parents, Ryan and Keri Topperwien, are devastated at the diagnosis after they were reassured at the time of the incident that their baby would not suffer any adverse reactions.
“I had thought in the very back of my mind that the absolute worst thing they could say is leukaemia,” Mrs Topperwien said. “When they said that he had it, it blindsided both of us.”
The couple, both 27, were horrified when at six weeks old their son was given the vaccination meant for teenage girls instead of one to prevent meningitis.
Read the Full Article here

Ecco cosa puó scatenare un danno da vaccino!!!!
Negate pure ma pregate Dio non vi capiti mai!!!!
E questo da quel maledettissimo giorno…prima di iniziare la cura passavamo intere giornate cosí adesso siamo arrivati a una al giorno!
Giuro su Dio che ti tiro fuori da questo inferno!!!!
Piano piano tutto questo sarà solo un bruttissimo ricordo parola di mamma

Per approfondimenti. https://m.facebook.com/corolaita/
Here’s what can trigger vaccine damage!!!!
DENY It, but pray to God you never understand!!!!
And that from that bloody day… before we started the cure, we spent whole days like this.
I swear to God I’ll get you out of this hell!!!!
Plan plan all this will be just a terrible memory of mom
For further information. https://m.facebook.com/corolaita/

Not Just Autism, Major Yale Study Shows Vaccines Tied To Multiple Brain Disorders
Scientist found a strong correlation between vaccines and developing a brain disorder such as OCD, anorexia, ADHD, and major depressive disorders.
By: Jack Burns / The Free Thought Project It is no question that the subject of vaccines is profoundly controversial. On both sides of the argument exist truths and lies that can hinder the ability of some to make rational decisions.
For the last 50 years, the world has taken a front row seat to the phenomenological occurrences of the rise of brain disorders such as Autism, ADHD, and major depressive disorders. Anecdotally speaking, parents all over the globe have reported that one day their children were normal and growing healthily, and the next, after having gotten their vaccinations, they get Autism, or ADHD, for example.
While science and the government continue to maintain there’s no causal relation between the vaccines and the disorders, parents, multiple studies, and other countries have reported otherwise. Now, it seems, some very brave and unabashed scientists have been able to show a correlation of what many have known for quite some time.
It has also been proven that CDC scientists destroyed data that showed a correlation between vaccines and autism in children.
Researchers at Pennsylvania State and Yale University sought to examine, “whether antecedent vaccinations are associated with increased incidence of obsessive–compulsive disorder (OCD), anorexia nervosa (AN), anxiety disorder, chronic tic disorder, attention deficit hyperactivity disorder, major depressive disorder, and bipolar disorder in a national sample of privately insured children.”
Controlling for broken bones and open wounds (control means to use commonly occurring instances as a contrast method), the researchers concluded that someone who’d received the Flu vaccine within the last year “were also associated with incident diagnoses of AN, OCD, and an anxiety disorder.” These findings greatly expand the common understandings that vaccines are related to Autism and now include the other three brain-based illnesses.
The study used private insurance claims information as their means of collecting the data. “Using claims data, we compared the prior year’s occurrence of vaccinations in children and adolescents aged 6–15 years with the above neuropsychiatric disorders that were newly diagnosed between January 2002 and December 2007,” the study writes.
Moreover, the correlations were not limited to the Flu vaccine either. According to the published study found in the Journal Frontiers in Psychiatry, “Several other associations were also significant with HRs greater than 1.40 (hepatitis A with OCD and AN; hepatitis B with AN,” meaning the hepatitis vaccines are also implicated in causing brain disorders.

CDC Scientist Admits they Destroyed Data that Showed Vaccines Caused Autism in Children
It is no question that the subject of vaccines is profoundly controversial. On both sides of the argument exist truths and lies that can hinder the ability of some to make rational decisions.
While we have everyone from attorneys to biologists, to political scientists who write for the Free Thought Project, none of us are doctors, so we do not make recommendations about what you and your family should do in regards to vaccination. That being said, when we see critical information about vaccines being kept from the public, we will expose it every single time.
On October 24, activists rallied at the headquarters of the Centers for Disease Control and Prevention in Atlanta, Georgia. Their mission was clearly stated, “Truth, Transparency, and Freedom.”
The event called for “concerned individuals from all across the nation” to gather outside the CDC Headquarters and “demand truth, transparency and freedom-to-choose which medical procedures are right for themselves and their families.” The event states that the demonstration will be aimed at exposing “the corruption within the CDC’s vaccine division,” according to a report by Derrick Broze.
The organizers of the event were focusing on the lack of coverage given to the bombshell admission by a Senior Research Scientist within the CDC, Dr. William Thompson.
During 2014, Dr. Thompson had multiple discussions with a man named Dr. Brian Hooker “regarding vaccines and neurodevelopmental outcomes including autism spectrum disorders.”
Thompson was completely unaware that he was being recorded by Hooker during these conversations that subsequently led to a CDC cover-up being exposed.

Temporal Association of Certain Neuropsychiatric Disorders Following Vaccination of Children and Adolescents: A Pilot Case–Control Study
Results: Subjects with newly diagnosed AN were more likely than controls to have had any vaccination in the previous 3 months [hazard ratio (HR) 1.80, 95% confidence interval 1.21–2.68]. Influenza vaccinations during the prior 3, 6, and 12 months were also associated with incident diagnoses of AN, OCD, and an anxiety disorder. Several other associations were also significant with HRs greater than 1.40 (hepatitis A with OCD and AN; hepatitis B with AN; and meningitis with AN and chronic tic disorder).
Conclusion: This pilot epidemiologic analysis implies that the onset of some neuropsychiatric disorders may be temporally related to prior vaccinations in a subset of individuals. These findings warrant further investigation, but do not prove a causal role of antecedent infections or vaccinations in the pathoetiology of these conditions. Given the modest magnitude of these findings in contrast to the clear public health benefits of the timely administration of vaccines in preventing mortality and morbidity in childhood infectious diseases, we encourage families to maintain vaccination schedules according to CDC guidelines.

 

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Vaccine News – A study from West Africa’s Guinea-Bissau discovered that all-cause infant mortality more than doubled after the introduction of the DTP vaccination

The Alex Jones Channel – Shocking! Elmo Lies To Children About Vaccine Safety / Laughs At Autistic Victim

The First 6 Years Of A Fully Vaccinated Child’s Life Looks Like This…
We want you to have a choice. We want you to always know the facts. No laws should govern your child’s medical decisions, only you should.
Here is a comprehensive list of what your child receives if you fully vaccinate them for the first six years of their life.
Source: “What The Pharmaceutical Companies Don’t Want You To Know About Vaccines” – By Dr. Todd M. Elsner. Todd’s book is available on Amazon here.
Dr. Tenpenny’s Book is currently available on Amazon

17,500 mcg 2-phenoxyethanol (antifreeze)
5,700 mcg aluminum (neurotoxin)
Unknown amounts of fetal bovin serum(aborted cow blood)
801.6 mcg formaldehyde (carcinogen, embalming agent)
23,250 mcg gelatin (ground up animal carcuses)
500 mcg human albumin (human blood)
760 mcg of monosodium L-glutamate (causes obesity & diabetis)
Unknown amounts of MRC-5 cells (aborted human babies)
Over 10 mcg neomycin (antibiotic)
Over 0.075 mcg polymyxin B (antibiotic)
Over 560 mcg polysorbate 80 (carcinogen)
116 mcg potassium chloride (used in lethal injection)
188 mcg potassium phosphate (liquid fertilizer agent)
260 mcg sodium bicarbonate (baking soda)
70 mcg sodium borate (Borax, used for cockroach control)
54,100 mcg of sodium chloride (table salt)
Unknown amounts of sodium citrate (food additive)
Unknown amounts of sodium hydroxide (Danger! Corrosive)
2,800 mcg sodium phosphate (toxic to any organism)
Unknown amounts of sodium phosphate monobasic monohydrate (toxic to any organism)
32,000 mcg sorbitol (Not to be injected)
0.6 mcg streptomycin (antibiotic)
Over 40,000 mcg sucrose (cane sugar)
35,000 mcg yeast protein (fungus)
5,000 mcg urea (metabolic waste from human urine)
Other chemical residuals

What The Pharmaceutical Companies Don’t Want You To Know About VACCINES… Paperback – 2009
This book is a must read for parents, soon to be parents and physicians who regularly administer vaccines. There are over 500 pages of information proving that vaccines are not responsible for the eradication of communicable disease; vaccines have done nothing but promote chronic disease and illness; and vaccines contain the most toxic chemicals known to man. Furthermore, there are close to 2,000 references that back up the information in this book. The references are from studies published in peer reviewed medical journals, the Centers for Disease Control and Prevention, the Food and Drug Administration, the prestigious Institute of Medicine, and from the United States Congressional Reform Committee. Lastly, this book contains all the U.S. licensed vaccines and the ingredients each vaccine contains. The ingredients of each vaccine come directly from the pharmaceutical companies’ vaccine package insert which are cross referenced with the National Library of Medicine for their human health effects-You will be SHOCKED at the side effects these vaccine ingredients have on the human body! FACT: If anyone from the medical community wants to argue with the information in this book, they will argue among themselves-it is their information!

Ever wonder WHY we NEED a religious exemption from vaccines?
Are you aware that some vaccines are made from ABORTIONS?
Marcella Piper-Terry explains in detail how abortions are used in vaccine manufacturing and the implications of that.
Interview by Polly Tommey and camera by Joshua Coleman and Anu Vaidya with editing by Joshua Coleman.

#RFKCommission #Vaxxed

Countless teenage girls suffer paralysis, blood clots, brain damage and chronic pain from force-vaccination of Gardasil’s HPV “shot in the dark”
Friday, March 17, 2017 by: S.D. Wells
(Natural News) A sexually transmitted disease called human papillomavirus (HPV) is the only form of cancer known to be contagious, but what the medical community won’t tell parents of teenagers and preteens is that HPV is easily defeated by a normal functioning immune system. Of the 120 or more different strains of HPV, only about 15 are carcinogenic, and the HPV vaccines, which have never been proven safe or effective in any clinical trials, literally take a shot in the dark at a couple of these strains, much like the haphazard flu shot administered every year to tens of millions of unsuspecting victims of neurological poisoning.
Still, the CDC and rogue hacks and shills from Big Pharma use scare tactics to all but force-vaccinate girls as young as 9-years-old with sodium chloride and two versions of the dormant HPV cancers hidden in protein and genetically modified organisms.
Scare tactics and medical propaganda con mothers into getting their young daughters jabbed with deadly neurotoxins
“You won’t be able to have children if you get cervical cancer.” “You can catch cancer from having sex and die.” “The shot will make you immune to cancer.” “The shot prevents cancer.” “You wanna have children later? You better get this shot.” The propaganda is mind-blowing, and it unfortunately works. It convinces parents to do the unthinkable: have their little girls (and boys) jabbed with some of the most dangerous carcinogens on earth to “prevent” a couple of strains of a rather benign, pre-cancerous STD. It doesn’t even make sense. What’s even worse is that the HPV vaccine’s protection effect wears off after a few years (as does the cancer itself under normal immune conditions), so what’s the use of taking the risk of getting jabbed with all these neurotoxins? Just how young are kids becoming promiscuous enough to worry about STDs anyhow?
More than 10,000 adverse events have been reported from victims of the HPV scam, including blood clots in the heart and lungs, anaphylactic shock, loss of muscle use and seizures. Most infections from HPV are benign and cleared rapidly by the human immune system and never progress to cervical cancer, or even precancerous lesions of the vagina, vulva or anus. No valid reason for administering the HPV vaccine has ever even been established.
Why are HPV vaccines, like Gardasil (made by Merck) and Cervarix (made by GSK) so dangerous? Answer: They’re made with “denatured” forms and fragmented strains of the virus, meaning the virus is weakened and can remain dormant for months, if not years, so if you do get the virus later, who’s to say you didn’t get it from the vaccine itself? No studies on this have ever been conducted, nor will they likely ever be. Plus, Gardasil contains aluminum, sodium chloride, polysorbate 80 and l-histidine, the latter of which interferes with the brain’s defenses against metal toxins. That means the aluminum has a heightened chance of crossing the blood/brain barrier. Got brain damage? No wonder. The following are just four examples of the hundreds (if not thousands) of girls permanently damaged by HPV vaccines.

Stronger More Toxic Gardasil Vaccine Approved by FDA: Will More Girls Suffer and Die?
March 23, 2017
Malfeasance is when a public official violates the public trust by performing an act that is wrongful, legally unjustified, or contrary to law. Nonfeasance is the failure to act where there is a duty to act. Misfeasance is conduct that is lawful but inappropriate. Perhaps, when it comes to the recent approval of Gardasil 9 all of these apply.
10 December 2014: The FDA approved the use of a reportedly “new and improved” version of Gardasil, which will be marketed as Gardasil 9. According to the FDA approval letter, this action was taken without consultation with VRBPAC (the Vaccines and Related Biological Products Advisory Committee) which is responsible for reviewing and evaluating data concerning the safety, effectiveness, and appropriate use of vaccines and related biological products.
The FDA approval letter, signed by Marion Gruber, Director of Office of Vaccines Research and Review CBER,  states the reason for bypassing the advice of VRBPAC writing:
”We did not refer your application to the Vaccines and Related Biological Products Advisory Committee because our review of information submitted in your BLA, including the clinical study design and trial results, did not raise concerns or controversial issues which would have benefited from an advisory committee discussion.”
So, the Office of Vaccines Research and Review, Center for Biologics Evaluation and Research (CBER) committee took it upon themselves to decide there were ”no concerns or controversial issues” regarding the approval of Gardasil 9?
This division of CBER decided there would be no benefit from ”an advisory committee discussion”?
According to their own mission statement, the FDA is ”responsible for protecting the public health by assuring the safety, efficacy and security of human and veterinary drugs, biological products, medical devices, our nation’s food supply, cosmetics, and products that emit radiation.”
The FDA, and all committees associated with the FDA, are public officials and therefore obliged to act in the public’s best interest particularly when it comes to health and safety issues.
Is bypassing advisory committee discussions regarding Gardasil 9’s potential safety and efficacy acting in the public’s best interest, or is it malfeasance, nonfeasance and/or misfeasance?
Gardasil 9 Facts: More than DOUBLE the amount of Toxic Aluminum!
CBER decided there was no need for VRBPAC to review or evaluate any data concerning the safety, effectiveness, and appropriate use of Merck’s proposed Gardasil 9 vaccine before making a decision to approve the nine-valent HPV vaccine. This move is particularly disturbing when one considers the worldwide controversy surrounding Gardasil’s safety, effectiveness and appropriate use.

Studies about the aluminium toxicity on humans
Gardasil 9 insert
Gardasil insert

Dr. Yehuda Shoenfeld says vaccines cause auto-immunity. It’s really not a question of “IF” there are adverse events from vaccines, it’s a question of “how often?”, “how severe?”, and whether it’s worth the trade-off? You can listen to the pre-eminent expert on vaccine-induced autoimmunity in the world, or you can go to your mainstream pediatrician who will tell you that vaccines have “no risk, lots of benefits.” It’s really up to you!
This is just a clip from his talk, entire talk in comments below, as well as Dr. Shoenfeld’s new TEXTBOOK, called “Vaccines and Autoimmunity”!
By the way, “autoimmunity” includes all the crazy epidemics in our kids that weren’t around in the 1980s or earlier: asthma, food allergies, skin rashes, etc. “Some of the main examples of autoimmune disorders include diabetes mellitus type 1 (IDDM), systemic lupus erythematosus (SLE), Hashimoto’s thyroiditis, Graves’ disease of the thyroid, Sjögren’s syndrome, Churg-Strauss Syndrome, Coeliac disease, rheumatoid arthritis (RA), and idiopathic thrombocytopenic purport.”
Listen to Dr. Shoenfeld: “Dr. Yehuda Shoenfeld is on the editorial board of 43 journals in the fields of rheumatology and autoimmunity and is the founder and editor of the Israel Medical Association Journal, the representative journal of science and medicine in the English language in Israel. He is also is the founder and editor of “Autoimmunity Reviews” and co-editor of “The Journal of Autoimmunity”. His clinical and scientific works focus on autoimmune and rheumatic diseases, and he has published more than 1700 papers in journals such as the New England Journal of Medicine, Nature, the Lancet, the Proceedings of the National Academy of Sciences of the United States of America, the Journal of Clinical Investigation, the Journal of Immunology, Blood, the Journal of the Federation of American Societies for Experimental Biology, the Journal of Experimental Medicine, Circulation, Cancer, and others, and his articles have had over 31,000 citations. He has written more than three hundred and fifty chapters in books, and has authored and edited 25 books.”

A study from West Africa’s Guinea-Bissau discovered that all-cause infant mortality more than doubled after the introduction of the DTP vaccination.
An observational study from the West African country Guinea-Bissau titled, “The Introduction of Diphtheria-Tetanus-Pertussis and Oral Polio Vaccine Among Young Infants in an Urban African Community: A Natural Experiment,” [i] examined the introduction of diphtheria-tetanus-pertussis (DTP) and oral polio vaccine (OPV) in an urban community in Guinea-Bissau in the early 1980s. The World Health Organization introduced the Expanded Program on Immunization (EPI) in low-income countries in the 1970s with the goal of universal immunization for all children. In the introduction, the study’s authors state, “Except for the measles vaccines, surprisingly few studies examined the introduction of vaccines and their impact on child survival.”
The purpose of the study was to examine what happens to child survival when DTP and OPV were introduced in low-income countries. A community study [ii] of the state of nutrition and family structure found that severe malnutrition was not evident in urban Guinea-Bissau although it was initially assumed to be the main cause of the under-five mortality rate.
The study findings emerged from a child population that had been followed with 3-monthly nutritional weighing sessions since 1978. From June 1981 DTP and OPV were offered from 3 months of age at these sessions. Due to the 3-monthly intervals between sessions, the children were allocated by birthday in a ‘natural experiment’ to receive vaccinations early or late between 3 and 5 months of age. The study included children who were greater than 6 months of age when vaccinations started and children born until the end of December 1983. The researchers compared mortality between 3 and 5 months of age of DTP-vaccinated and not-yet-DTP- vaccinated children in Cox proportional hazard models.
When mortality was compared, the mortality hazard ratio (HR) among 3-5-month-old children having received the DTP (±OPV) was 5.00 compared with not-yet-DTP-vaccinated children [i.e. a 400% increase]. According to the authors, differences in background factors did not explain the effect. All-cause infant mortality after 3 months of age increased after the introduction of these vaccines (2.12 (1.07–4.19)) [i.e. a 212% increase]. However, the study findings revealed the negative effect was particularly strong for children who had received DTP-only and no OPV (10.0 (2.61–38.6)).
The researchers concluded:
“DTP was associated with increased mortality; OPV may modify the effect of DTP.”

Study – The Introduction of Diphtheria-Tetanus-Pertussis and Oral Polio Vaccine Among Young Infants in an Urban African Community: A Natural Experiment
Abstract
Background
We examined the introduction of diphtheria-tetanus-pertussis (DTP) and oral polio vaccine (OPV) in an urban community in Guinea-Bissau in the early 1980s.
Methods
The child population had been followed with 3-monthly nutritional weighing sessions since 1978. From June 1981 DTP and OPV were offered from 3 months of age at these sessions. Due to the 3-monthly intervals between sessions, the children were allocated by birthday in a ‘natural experiment’ to receive vaccinations early or late between 3 and 5 months of age. We included children who were <6 months of age when vaccinations started and children born until the end of December 1983. We compared mortality between 3 and 5 months of age of DTP-vaccinated and not-yet-DTP-vaccinated children in Cox proportional hazard models.
Results
Among 3–5-month-old children, having received DTP (±OPV) was associated with a mortality hazard ratio (HR) of 5.00 (95% CI 1.53–16.3) compared with not-yet-DTP-vaccinated children. Differences in background factors did not explain the effect. The negative effect was particularly strong for children who had received DTP-only and no OPV (HR = 10.0 (2.61–38.6)). All-cause infant mortality after 3 months of age increased after the introduction of these vaccines (HR = 2.12 (1.07–4.19)).
Conclusion
DTP was associated with increased mortality; OPV may modify the effect of DTP.