Vaccine News – VAXXED TV – I’ve waited 30 years to tell my story & A PROFILE OF AUTISM IN AUSTRALIA

Journal of Molecular and Genetic Medicine – February 19, 2014

Study – Review of Vaccine Induced Immune Overload and the Resulting Epidemics of Type 1 Diabetes and Metabolic Syndrome, Emphasis on Explaining the Recent Accelerations in the Risk of Prediabetes and other Immune Mediated Diseases

Abstract
There has been an epidemic of inflammatory diseases that has paralleled the epidemic on iatrogenic immune stimulation with vaccines. Extensive evidence links vaccine induced immune over load with the epidemic of type 1 diabetes. More recent data indicates that obesity, type 2 diabetes and other components of metabolic syndrome are highly associated with immunization and may be manifestations of the negative feedback loop of the immune system reacting to the immune overload. The epidemic of diabetes/prediabetes appears to be accelerating at a time when the prevalence of obesity has stabilized, indicating that the negative feedback system of the immune system has been over whelmed. The theory of vaccine induced immune overload can explain the key observations that have confounded many competing hypothesis. The current paper reviews the evidence that vaccine induced immune overload explains the disconnect between the increase in prediabetes and nonalcoholic fatty liver at a time when the obesity epidemic is waning in children.

 

 

 

 

Dr Dale Brown – A Young Doctor Dies after Receiving the Flu Shot
A doctor with a true heart of service to help people has died after suffering a serious paralytic injury after the flu vaccine. The US Court of Federal Claims “Vaccine Court” has awarded $500,000 to the beneficiary of this doctor after her vaccine injuries lead to her paralysis, multiple organ failure and eventual death.
This is heartbreak for anyone. To see such a good, caring, and servant to the Lord be taken from this world far before her time. I have read this doctor’s obituary and anyone can see that this woman was a very caring person who had a heart to serve others. What should upset and frustrate any of us is when you see the fact that vaccines like the flu vaccine are forces against unwilling nurses, doctors and other hospital staff.
The fact is that the flu vaccine is worthless, one could potentially argue that “yes the flu vaccine does cause injuries and even deaths, but it’s all for the ‘greater good’.” But the fact is the research proves that healthcare workers are not healthier and their patients are NOT protected by the vaccines.
Links to referenced research articles can be found at thewilddoc.com.
Visit thewilddoc.com or call 931-591-2010 to setup an online or in-office consultation.

Check out our other videos:
Are Vaccines Being Used For Population Control?

 

 

 

 

 

Flu Shots Are Fraud Part 1

 

 

A PROFILE OF AUTISM IN AUSTRALIA

Autism may present substantial challenges for those affected, their families and friends. It can also have an impact on a person’s education, as well as their social and economic participation.
In recent years an increasing number of Australians with Autism have been identified. There are numerous factors that may contribute to this increase in reporting. The results from the 2015 Survey of Disability, Ageing and Carers can provide insights into this complex and varied condition.

There were 164,000 Australians with Autism in 2015
The number of Australians with Autism increased by 42.1% since 2012
4 out of 5 people with Autism were male
More than 3/4 of those with Autism were young (5-24 years)
Almost 2/3 of those with Autismhad profound or severe disability
Almost 3/4 of those with Autism needed help with cognitive and emotional tasks
Almost of half of those with Autism needed help with communication
Around 4 out of 5 children2 with Autism had difficulties at school
40.8% of people with Autism participated in the workforce, compared with 83.2% people with no reported disability

Estimated Prevalence of Children With Diagnosed Developmental Disabilities in the United States, 2014–2016

Key findings Data from the National Health Interview Survey
● During 2014–2016, the prevalence of children aged 3–17 years who had ever been diagnosed with a developmental disability increased from 5.76% to 6.99%.
● During this same time, the prevalence of diagnosed autism spectrum disorder and intellectual disability did not change significantly.
● The prevalence of autism spectrum disorder, intellectual disability, other developmental delay, and any developmental disability was higher among boys compared with girls.
● The prevalence of any developmental disability was lower among Hispanic children compared with children in all other race and ethnicity groups.

 

 

 

VAXXED TV – Gardasil HPV vaccine killed my daughter

 

 

 

 

 

 

Multiple injuries in my family

My daughter is unvaccinated and super healthy

Immigration vaccines injured me

HERD IMMUNITY: Whooping Cough
Dr. Suzanne Humphries, MD discusses the fallacies about herd immunity and it’s relation to whooping cough.

Vaxxed/Unvaccinated in my family

 

Story and Q&A

I’ve waited 30 years to tell my story

My Unvaccinated 25 year old daughter

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ONE FOR ISRAEL Ministry – Jewish Johnathan Ben-David forgave his killer and you would not believe why!!!

How to accept Jesus Christ as your personal Saviour

Testimony by Phil Robertson from Duck Dynasty

1 Corinthians 15 Authorized (King James) Version (AKJV)
1 Moreover, brethren, I declare unto you the gospel which I preached unto you, which also ye have received, and wherein ye stand;
2 by which also ye are saved, if ye keep in memory what I preached unto you, unless ye have believed in vain.
3 For I delivered unto you first of all that which I also received, how that Christ died for our sins according to the scriptures;
4 and that he was buried, and that he rose again the third day according to the scriptures:

Hebrews 6 Authorized (King James) Version (AKJV)
1 Therefore leaving the principles of the doctrine of Christ, let us go on unto perfection; not laying again the foundation of repentance from dead works, and of faith toward God,
2 of the doctrine of baptisms, and of laying on of hands, and of resurrection of the dead, and of eternal judgment.
3 And this will we do, if God permit.
4 For it is impossible for those who were once enlightened, and have tasted of the heavenly gift, and were made partakers of the Holy Ghost,
5 and have tasted the good word of God, and the powers of the world to come,
6 if they shall fall away, to renew them again unto repentance; seeing they crucify to themselves the Son of God afresh, and put him to an open shame.
7 For the earth which drinketh in the rain that cometh oft upon it, and bringeth forth herbs meet for them by whom it is dressed, receiveth blessing from God:
8 but that which beareth thorns and briers is rejected, and is nigh unto cursing; whose end is to be burned.

Isaiah 53 – Old testament Prophecy about Jesus

1 Who hath believed our report? and to whom is the arm of the Lord revealed?
2 For he shall grow up before him as a tender plant,and as a root out of a dry ground:he hath no form nor comeliness;and when we shall see him,there is no beauty that we should desire him.
3 He is despised and rejected of men;a man of sorrows, and acquainted with grief:and we hid as it were our faces from him;he was despised, and we esteemed him not.
4 Surely he hath borne our griefs,and carried our sorrows:yet we did esteem him stricken,smitten of God, and afflicted.
5 But he was wounded for our transgressions,he was bruised for our iniquities:the chastisement of our peace was upon him;and with his stripes we are healed.
6 All we like sheep have gone astray;we have turned every one to his own way;and the Lord hath laid on him the iniquity of us all.
7 He was oppressed, and he was afflicted,yet he opened not his mouth:he is brought as a lamb to the slaughter,and as a sheep before her shearers is dumb,so he openeth not his mouth.
8 He was taken from prison and from judgment:and who shall declare his generation? for he was cut off out of the land of the living:for the transgression of my people was he stricken.
9 And he made his grave with the wicked,and with the rich in his death;because he had done no violence,neither was any deceit in his mouth.
10 Yet it pleased the Lord to bruise him;he hath put him to grief:when thou shalt make his soul an offering for sin,he shall see his seed, he shall prolong his days,and the pleasure of the Lord shall prosper in his hand.
11 He shall see of the travail of his soul, and shall be satisfied:by his knowledge shall my righteous servant justify many;for he shall bear their iniquities.
12 Therefore will I divide him a portion with the great,and he shall divide the spoil with the strong;because he hath poured out his soul unto death:and he was numbered with the transgressors;and he bare the sin of many,and made intercession for the transgressors.

 

Vaccine News – Study – Blood Levels of Mercury Are Related to Diagnosis of Autism: A Reanalysis of an Important Data Set & VAXXED TV – Vaccines gave my son autism

A study published in the Journal of Child Neurology examined the question of what is leading to the apparent increase in autism. They expressed that if there is any link between autism and mercury, it is crucial that the first reports of the question are not falsely stating that no link occurs. Researchers determined that a significant relation does exist between the blood levels of mercury and the diagnosis of an autism spectrum disorder.

Journal of Child Neurology
First Published November 1, 2007

Study – Blood Levels of Mercury Are Related to Diagnosis of Autism: A Reanalysis of an Important Data Set

M. Catherine DeSoto, PhD, Robert T. Hitlan, PhD
Department of Psychology, University of Northern Iowa, Cedar Falls, Iowa,

Abstract
The question of what is leading to the apparent increase in autism is of great importance. Like the link between aspirin and heart attack, even a small effect can have major health implications. If there is any link between autism and mercury, it is absolutely crucial that the first reports of the question are not falsely stating that no link occurs. We have reanalyzed the data set originally reported by Ip et al. in 2004 and have found that the original p value was in error and that a significant relation does exist between the blood levels of mercury and diagnosis of an autism spectrum disorder. Moreover, the hair sample analysis results offer some support for the idea that persons with autism may be less efficient and more variable at eliminating mercury from the blood.

A study published in the Journal of Child Neurology noted that autistic spectrum disorders can be associated with mitochondrial dysfunction. Researchers determined that children who have mitochondrial-related dysfunctional cellular energy metabolism might be more prone to undergo autistic regression between 18 and 30 months of age if they also have infections or immunizations at the same time.

Journal of Child Neurology
First Published February 1, 2006

Study – Developmental Regression and Mitochondrial Dysfunction in a Child With Autism
1 – Jon S. Poling, MD, PhD, 2 – Richard E. Frye, MD, PhD, 3 – John Shoffner, MD, 4 – Andrew W. Zimmerman, MD
1 – Department of Neurology and Neurosurgery Johns Hopkins Hospital Baltimore, MD
2 – Department of Neurology Boston Children’s Hospital Boston, MA
3 – Horizon Molecular Medicine Georgia State University Atlanta, GA
4 – Department of Neurology and Neurosurgery Johns Hopkins Hospital Kennedy Krieger Institute Baltimore, MD

Abstract
Autistic spectrum disorders can be associated with mitochondrial dysfunction. We present a singleton case of developmental regression and oxidative phosphorylation disorder in a 19-month-old girl. Subtle abnormalities in the serum creatine kinase level, aspartate aminotransferase, and serum bicarbonate led us to perform a muscle biopsy, which showed type I myofiber atrophy, increased lipid content, and reduced cytochrome c oxidase activity. There were marked reductions in enzymatic activities for complex I and III. Complex IV (cytochrome c oxidase) activity was near the 5% confidence level. To determine the frequency of routine laboratory abnormalities in similar patients, we performed a retrospective study including 159 patients with autism (Diagnostic and Statistical Manual of Mental Disorders-IV and Childhood Autism Rating Scale) not previously diagnosed with metabolic disorders and 94 age-matched controls with other neurologic disorders. Aspartate aminotransferase was elevated in 38% of patients with autism compared with 15% of controls (P < .0001). The serum creatine kinase level also was abnormally elevated in 22 (47%) of 47 patients with autism. These data suggest that further metabolic evaluation is indicated in autistic patients and that defects of oxidative phosphorylation might be prevalent.

A study conducted by Massachusetts General Hospital at the Centre for Morphometric Analysis by the department of Paediatric Neurology illustrates how autistic brains have a growth spurt shortly after birth and then slow in growth a few short years later. Researchers have determined that neuroinflammation appears to be present in autistic brain tissue from childhood through adulthood. The study excerpt reads:
“Oxidative stress, brain inflammation and microgliosis have been much documented in association with toxic exposures including various heavy metals. The awareness that the brain as well as medical conditions of children with autism may be conditioned by chronic biomedical abnormalities such as inflammation opens the possibility that meaningful biomedical interventions may be possible well past the window of maximal neuroplasticity in early childhood because the basis for assuming that all deficits can be attributed to fixed early developmental alterations in net”

US National Library of Medicine
National Institutes of Health – 2005

Study – Large brains in autism: the challenge of pervasive abnormality

Herbert MR.
Author information
Pediatric Neurology, Center for Morphometric Analysis, Massachusetts General Hospital, Charleston, MA 02129, USA. mherbert1@partners.org

Abstract
The most replicated finding in autism neuroanatomy-a tendency to unusually large brains-has seemed paradoxical in relation to the specificity of the abnormalities in three behavioral domains that define autism. We now know a range of things about this phenomenon, including that brains in autism have a growth spurt shortly after birth and then slow in growth a few short years afterward, that only younger but not older brains are larger in autism than in controls, that white matter contributes disproportionately to this volume increase and in a nonuniform pattern suggesting postnatal pathology, that functional connectivity among regions of autistic brains is diminished, and that neuroinflammation (including microgliosis and astrogliosis) appears to be present in autistic brain tissue from childhood through adulthood. Alongside these pervasive brain tissue and functional abnormalities, there have arisen theories of pervasive or widespread neural information processing or signal coordination abnormalities (such as weak central coherence, impaired complex processing, and underconnectivity), which are argued to underlie the specific observable behavioral features of autism. This convergence of findings and models suggests that a systems- and chronic disease-based reformulation of function and pathophysiology in autism needs to be considered, and it opens the possibility for new treatment targets.

VAXXED TV – Unvaccinated family with no cancer

Vaccines ruined my daughters life

No more vaccines for my children

My son had food allergies and autism from vaccines

Vaccines gave my son autism

Unvaccinated and healthy #vaxxed #Praybig

Vaccines have my son autism and epilepsy

Vaccines have completely destroyed my son

I’m a former pro vaccine nurse

Vaccines destroyed my family

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How to accept Jesus Christ as your personal Saviour

Testimony by Phil Robertson from Duck Dynasty

1 Corinthians 15 Authorized (King James) Version (AKJV)
1 Moreover, brethren, I declare unto you the gospel which I preached unto you, which also ye have received, and wherein ye stand;
2 by which also ye are saved, if ye keep in memory what I preached unto you, unless ye have believed in vain.
3 For I delivered unto you first of all that which I also received, how that Christ died for our sins according to the scriptures;
4 and that he was buried, and that he rose again the third day according to the scriptures:

Hebrews 6 Authorized (King James) Version (AKJV)
1 Therefore leaving the principles of the doctrine of Christ, let us go on unto perfection; not laying again the foundation of repentance from dead works, and of faith toward God,
2 of the doctrine of baptisms, and of laying on of hands, and of resurrection of the dead, and of eternal judgment.
3 And this will we do, if God permit.
4 For it is impossible for those who were once enlightened, and have tasted of the heavenly gift, and were made partakers of the Holy Ghost,
5 and have tasted the good word of God, and the powers of the world to come,
6 if they shall fall away, to renew them again unto repentance; seeing they crucify to themselves the Son of God afresh, and put him to an open shame.
7 For the earth which drinketh in the rain that cometh oft upon it, and bringeth forth herbs meet for them by whom it is dressed, receiveth blessing from God:
8 but that which beareth thorns and briers is rejected, and is nigh unto cursing; whose end is to be burned.

 

Vaccine News – Study – Gender-selective toxicity of thimerosal

PubMed.gov – Mar.2009
Abstract
A recent report shows a correlation of the historical use of thimerosal in therapeutic immunizations with the subsequent development of autism; however, this association remains controversial. Autism occurs approximately four times more frequently in males compared to females; thus, studies of thimerosal toxicity should take into consideration gender-selective effects. The present study was originally undertaken to determine the maximum tolerated dose (MTD) of thimersosal in male and female CD1 mice. However, during the limited MTD studies, it became apparent that thimerosal has a differential MTD that depends on whether the mouse is male or female. At doses of 38.4-76.8mg/kg using 10% DMSO as diluent, seven of seven male mice compared to zero of seven female mice tested succumbed to thimerosal. Although the thimerosal levels used were very high, as we were originally only trying to determine MTD, it was completely unexpected to observe a difference of the MTD between male and female mice. Thus, our studies, although not directly addressing the controversy surrounding thimerosal and autism, and still preliminary due to small numbers of mice examined, provide, nevertheless, the first report of gender-selective toxicity of thimerosal and indicate that any future studies of thimerosal toxicity should take into consideration gender-specific differences.
PubMed.gov – 15.Mar.2010
Abstract
Mercury (Hg) exposure from dental amalgam fillings and thimerosal in vaccines is not a major health hazard, but adverse health effects cannot be ruled out in a small and more susceptible part of the exposed population. Individual differences in toxicokinetics may explain susceptibility to mercury. Inbred, H-2-congenic A.SW and B10.S mice and their F1- and F2-hybrids were given HgCl2 with 2.0 mg Hg/L drinking water and traces of (203)Hg. Whole-body retention (WBR) was monitored until steady state after 5 weeks, when the organ Hg content was assessed. Despite similar Hg intake, A.SW males attained a 20-30% significantly higher WBR and 2- to 5-fold higher total renal Hg retention/concentration than A.SW females and B10.S mice. A selective renal Hg accumulation but of lower magnitude was seen also in B10.S males compared with females. Differences in WBR and organ Hg accumulation are therefore regulated by non-H-2 genes and gender. Lymph nodes lacked the strain- and gender-dependent Hg accumulation profile of kidney, liver and spleen. After 15 days without Hg A.SW mice showed a 4-fold higher WBR and liver Hg concentration, but 11-fold higher renal Hg concentration, showing the key role for the kidneys in explaining the slower Hg elimination in A.SW mice. The trait causing higher mercury accumulation was not dominantly inherited in the F1 hybrids. F2 mice showed a large inter-individual variation in Hg accumulation, showing that multiple genetic factors influence the Hg toxicokinetics in the mouse. The genetically heterogeneous human population may therefore show a large variation in mercury toxicokinetics.
US National Library of Medicine – National Institutes of Health – Feb.2015
Results
Developmental Domain: ASD Diagnostic Criteria
Social Communication/Social Interaction
Deficits in social communication and social interaction are core factors in the diagnostic criteria of ASD. Impairments in social communication may present as abnormalities in eye contact, poor integration of verbal and nonverbal behaviors, and difficulties understanding the nonverbal communication of others (American Psychiatric Association, 2013). In some cases, persons with ASD may not participate in conversation or struggle with pragmatic language (American Psychiatric Association, 2013). Impairments in social interaction include difficulties with social-emotional reciprocity, failure to develop peer relationships, and reduced empathetic understanding and/or response (American Psychiatric Association, 2013).
There were 21 articles reviewed on social communication and social interaction in persons with ASD published between 1993 and 2013: 13 case-control studies, 7 cross-sectional studies, and 1 surveillance study. Nine studies were conducted in the United States and 12 studies were conducted at outside of the US. Of these 21 articles, 14 address social communication or other language abilities. In samples of children with varying cognitive abilities, some studies showed no significant differences in communication, conversational deficits, and language levels between males and females with ASD (Andersson et al., 2013; Dawson et al., 2007; Nicholas et al., 2008; Pilowsky et al., 1998; Park et al., 2012a, 2012b; Mayes and Calhoun, 2011; Mandy et al., 2012; Sipes et al., 2011; Solomon et al., 2012; Amr et al., 2011). One study found that males with ASD had greater expressive and receptive language skills than females with ASD (Carter et al., 2007) and another study found that females with ASD had more impaired social communication skills than males with ASD (Hartley and Sikora, 2009). Conversely, Park et al. (2012b) found that females with ASD had stronger non-verbal communication abilities than males with ASD. The majority of the literature reviewed on social communication found no difference between males and females with ASD, but there is some inconsistency.
The literature on sex differences in social interaction among persons with ASD (13 of 21 articles reviewed) is also inconsistent but generally suggests no significant sex differences in social interaction skills (Andersson et al., 2013; Dawson et al., 2007; Nicholas et al., 2008; Pilowsky et al., 1998; Mayes and Calhoun, 2011; Park et al. 2012b; Mandy et al., 2012; Sipes et al., 2011; Solomon et al., 2012). In population-level surveillance of eight-year olds, 80 % of children with ASD had poor social-emotional reciprocity with no significant difference between males and females (Nicholas et al., 2008). Szatmari et al. (2012) also found no sex differences in social-emotional reciprocity for children with varying cognitive abilities in a study from the Autism Genome Project. Oppositely, in an age and IQ matched case–control study, female adults with ASD were found to have fewer socio-communication difficulties during interpersonal interaction than male adults with ASD (Lai et al., 2013). Lastly, no sex differences have been noted in emotional reactiveness or being withdrawn (Hartley and Sikora, 2009) and in empathetic understanding and responses (Auyeung et al., 2009).
Cognitive functioning is likely to play a role in these social processes. Lower intellectual abilities are often linked with greater social impairment regardless of sex (Dawson et al., 2007). Among children with high functioning autism (IQ≥70), social skills have been found to be more impaired in female children than male children (Holtmann et al., 2007) and more severe as children aged (McLennan et al., 1993). In contrast, other studies found adult females with high functioning autism to have less socio-communication issues compared to males (Lai et al., 2011) or there were no sex differences in socio-communication skills in older children and adolescents (Holtmann et al., 2007; Kopp and Gillberg, 2011).
Overall, the 21 articles reviewed suggest no difference in social interaction between males and females with ASD and inconsistent differences in social communication between males and females with ASD, although both social interaction and social communication may be influenced by intellectual ability and age.
Restricted, Repetitive Patterns of Behavior, Interests, or Activities
There were 18 articles reviewed on restricted and repetitive patterns of behaviors and interests (RRBI) published between 1993 and 2013: nine cross-sectional studies, seven case–control studies, one cohort study, and one surveillance study. Eleven studies were conducted in the United States and seven studies were conducted in other countries. Based on this review, the literature suggests that males with ASD have more RRBI than females with ASD (Hattier et al., 2011; Carter et al., 2007). When assessing individual facets of RRBI, restricted interests are seen more often in males with ASD than females with ASD independent of cognitive ability (Kohane et al., 2012; May et al., 2012; Mandy et al., 2012; Szatmari et al., 2012). Males with ASD are also more likely to have more routines, rituals, and fascination with parts of objects than females with ASD (Nicholas et al., 2008; Park, et al., 2012b; Beuker et al., 2013). The literature on repetitive motor movements is less consistent: adult males with high functioning autism or Asperger’s syndrome had more repetitive motor movements than adult females with high functioning autism or Asperger’s syndrome in one case-control study (May et al., 2012), but there were no sex differences in repetitive motor movements among persons with autism in two other case-control studies (McLennan et al., 1993; Worley and Matson, 2011), one cross-sectional study (Auyeung et al., 2009), and one population-based cross-sectional study (Nicholas et al., 2008).
Age may influence the presentation of RRBI in males and females with ASD. One study found no sex difference among RRBI in toddlers (Sipes et al., 2011), whereas a different study found significantly more RRBI among adult males with ASD compared to females with ASD (Hattier et al., 2011). In summation, most studies reviewed suggested that males with ASD are likely to have more RRBI than females with ASD across levels of cognitive ability, although RRBI may be influenced by age.
Sensory issues are prevalent among persons with ASD (Nicholas et al., 2008) and are included as a RRBI in the DSM 5 (American Psychiatric Association, 2013). Common issues are oversensitivity to touch, sound, smell, taste, and attraction to certain tactile stimuli (American Psychiatric Association, 2013; Baranek et al., 2006; Rogers et al., 2003). Abnormal sensory reactions have been reported to occur in up to 47 % of persons with ASD, which is a rate ten times higher than reported in the general population (Nicholas et al., 2008). Additionally, there is a significant correlation between sensory issues in each of the individual senses (Kern et al., 2007); therefore, impairment is compounded for persons with ASD and sensory abnormalities.
Cross-sectional studies found no observed differences between males and females in sensitivity to sound (Mandy et al., 2012) or sensory sensitivity in general (Louisa et al., 2012; Mayes and Calhoun, 2011; Baranek et al., 2006). Mandy et al. (2012) examined RRBI in children and adolescents 3 to 18 years of age and found that age did not influence the presentation of RRBI. However, Lai et al. (2011) found that adult females with high functioning autism had more lifetime sensory issues than males with ASD. Overall, the majority of articles reviewed that addressed sensory issues in ASD do not suggest a sex difference, although aging may be a factor and should be further explored.
Developmental Domain: other Developmental Endophenotypes
Attention Deficit Hyperactivity Disorder
Attention deficit hyperactivity disorder (ADHD) and corresponding symptoms are common in children with ASD (Bradley and Isaacs, 2006; Nicholas et al., 2008). Previous studies show that 50 % to 83 % of children and teenagers with ASD had hyperactivity and attention problems (Nicholas et al., 2008; Bradley and Isaacs, 2006). There were seven articles that met search criteria and addressed ADHD. These seven articles were published between 2008 and 2012 with five cross-sectional studies and two cohort studies. Two studies were conducted in the United States and five were conducted in other countries.
A study of 7 to 12 year-olds with varying cognitive abilities found that males with ASD had higher levels of hyperactivity and impulsivity than females with ASD and this difference was more pronounced at younger ages (May et al., 2012). Males with high functioning autism from middle childhood to adolescence had higher levels of hyper-activity and inattention in teacher reports as compared to female peers, but there was no difference in parental reports (Mandy et al., 2012). A study of children and young adults aged 5 to 20 with high functioning autism found females had more attention problems (Bryson et al., 2008). A majority of studies found no difference in ADHD co-occurrence between males and females with ASD (Simonoff et al., 2008; Sinzig et al., 2009; Mayes and Calhoun, 2011; Horovitz et al., 2011). In summary, the current literature leans toward no sex differences in the co-occurrence of ADHD and ASD, but there is still inconsistency in the literature and thus, the sex difference is largely inconclusive
Challenging Behavior (Aggressiveness/Temper Tantrums/Oppositional Tendencies)
Challenging behavior is a common associated feature of ASD and includes aggression expressed toward other people, temper tantrums, and oppositional and defiant tendencies. Aggression expressed toward other people and temper tantrums are found in 50 % and 54 % of children with ASD compared to only 28 % and 23 % of children without ASD (Nicholas et al., 2008). The 12 articles in this review that met search criteria and addressed challenging behaviors were published between 2005 and 2012 and included six cross-sectional studies, four case–control studies, one clinical trial, and one surveillance study. Six studies were conducted in the United States and six were conducted in other countries. In general, there were no differences in aggression, temper tantrums, or anger between child sexes, regardless of age or cognitive ability (Kozlowski et al., 2012; Worley and Matson, 2011; Carter et al., 2007; Murphy et al., 2009; Mandy et al., 2012; Quek et al., 2012; Mayes and Calhoun, 2011; Horovitz et al., 2011). One study found that females with ASD had more “challenging behaviors” than males with ASD, although challenging behaviors were not explicitly defined (Dworzynski et al., 2012). Delinquent behavior (Park et al., 2012b) and oppositional defiance (Gadow et al., 2005) were more prevalent in males than in females with ASD in two studies reviewed.
Cognitive Skills and Intellectual Disability
In a review from 1966 to 2001, Fombonne (2003) found that the median prevalence of intellectual impairment in persons with ASD was 70 % in the studies evaluated. More recent population-based studies have found lower rates of ID in persons with ASD, with a range from 18 % to 55 % (Charman et al., 2011). The National Health Interview Study found 0.71 % of all children aged 3 to 17 from 1998 to 2007 had an ID (Boyle et al., 2011). Our review found 12 articles that met the search criteria and addressed ID or specific cognitive skills. These 12 articles were published between 1983 and 2011, and included seven cross-sectional studies, four case–control studies, and one-surveillance study. Four studies were conducted in the United States and eight were conducted in other countries.
The 12 articles reviewed support a relationship between child sex and co-occurring ID in children with ASD. The sex ratio between males and females without ID is greater than the sex ratio for all levels of cognitive ability combined (Nicholas et al., 2008; Hartley and Sikora, 2009). Consequently, the male to female ratio is lower when there is co-occurring ID compared to when there is no co-occurring ID (Hartley and Sikora, 2009; Nicholas et al., 2008; Yeargin-Allsopp et al., 2003). The ratio of males to females with ASD and co-occurring ID has been seen to range from 1.3:1 (Tsai and Beisler, 1983) to 2.8:1 (Bryson et al., 2008) with a trend toward fewer sex differences as ID becomes more severe (Yeargin-Allsopp et al., 2003). This differential sex difference in ID results in females with ASD, on average, having lower intelligence test scores than males with ASD (Banach et al., 2009; Volkmar et al., 1993).
Specific cognitive skills posited to vary between males and females with ASD include cognitive flexibility, response inhibition, working memory, and attention to detail (Geurts et al., 2004). Female adolescents with high functioning autism were seen to have superior information processing, multiple conceptual tracking, divided attention, and cognitive flexibility compared to male adolescents with high functioning autism (Bolte et al., 2011). In contrast, studies show males with ASD have superior attention to detail, visuo-spatial skills (Auyeung et al., 2009), and inhibitory control (Lemon et al., 2011) compared to females with ASD. There were no sex differences between adults with ASD in the “eyes test” which measures ability to infer mental states through the eyes (Lai et al., 2011). In summary, the 12 journal articles reviewed in this section suggest that females with ASD generally have lower intelligence test scores than males with ASD and that specific cognitive skills may vary by sex.
Developmental Regression
Parents of some children with ASD report a period of typical development followed by a loss in language, social, motor, self-help, imaginative play, or other skills. This developmental regression is usually reported to occur between 15 and 24 months of age (Meilleur and Fombonne, 2009). Our review found six articles that met search criteria and addressed developmental regression. These six articles were published between 2007 and 2013 and comprised two cohort studies, three cross-sectional studies, and one surveillance study. In a population-based surveillance study of children with ASD, 17 % of children had documented developmental regression and that percentage rose if the child had a previous ASD diagnosis (Wiggins et al., 2009). Males had significantly more regression than females and were more likely to regress at a younger age (Wiggins et al., 2009). This higher risk of regression in males was also seen in smaller, non-population based studies (n=4, 8, and 17 female children) (Bernabei et al., 2007; Ekinci et al., 2012; Zhang et al., 2012). In contrast, a cross-sectional study found that females aged 18 months to 15 years had significantly higher occurrence of regression as compared to males (30 % vs. 19 %) (Ben-Itzchak et al., 2013). No difference in the presence of developmental regression between males and females with ASD was observed in a small clinical sample of 20 females (Meilleur and Fombonne, 2009). In sum, the review of sex differences of developmental regression is contradictory and thus inconclusive.
Excess/Absence of Fear
Excess or absence of fear is more common in children with ASD than other children (Evans et al. 2005; Nicholas et al., 2008). In a population-based surveillance of eight-year olds, Nicholas et al. (2008) found that 32 % of children with ASD had atypical fear noted in service records compared to 6 % of children with ASD symptoms but no ASD diagnosis. Three articles met search criteria and addressed excess or absence of fear. All three of these articles were published in the United States between 1990 and 2011 and were two cross-sectional studies and one case–control study. In these studies, females with ASD had more specific phobias than males with ASD (Gadow and DeVincent, 2012; Matson and Love, 1990) and more unusual fears (Mayes et al., 2013). One study conducted by Matson and Love (1990) found more fear in typically developing female children compared to male children and no significant difference in fear between typically developing female children and female children with ASD. Given the sparse amount of research on this topic, further exploration is warranted to understand sex differences in fear among persons with ASD.
Safety Issues (Self-Injury/Elopement)
About 50 % of children with ASD engage in self-injurious behavior (Richards et al., 2012; Baghdadli et al., 2003; Duerden et al., 2012). Four studies met search criteria and three pertained to self-injurious behavior. All three of these studies were cross-sectional designs with two being conducted in Europe and one in the United States. No difference in self-injurious behavior was found between males and females with ASD (Richards et al., 2012; Baghdadli et al., 2003; Duerden et al., 2012).
Elopement, also known as wandering off, is a rising concern among parents of children with ASD. One online survey addressing elopement met our search criteria. This survey was conducted in the United States in 2013 and found that 49 % of parents reported that their child with an ASD wandered off at least once after the age of four years (Anderson et al., 2012). Results also found that sex did not influence the prevalence of elopement, although children with more intellectual impairment were more likely to elope (Anderson et al., 2012). Few conclusions can be drawn since there is little research on elopement and other safety issues in children with ASD and associated sex differences.
Psychiatric Domain
Anxiety/Mood Disorders
Symptoms of anxiety and mood disorders are more prevalent in children with ASD than in typically developing children (Worley and Matson, 2011; Nicholas et al., 2008). Among children who met a surveillance definition for an ASD, 55 % had abnormal mood or affect compared to 26 % of children with at least one symptom of an ASD but no ASD diagnosis (Schendel et al., 2009). The Special Needs Autism Project in the UK found 44 cases of emotional disorder per 100 children with ASD (Simonoff et al., 2008). Moreover, among eight-year-old children who met a surveillance definition for an ASD, 3 % had anxiety, 2 % had emotional disorder, 2 % had mood disorder, and less than 2 % had obsessive-compulsive disorder (OCD), depression, bipolar, or oppositional defiant disorder (Levy et al., 2010). Nine studies were found that met search criteria and addressed anxiety or mood disorders. These nine studies were published between 2005 and 2012 and included five cross-sectional studies and four case–control studies. Four of the studies were conducted in the United States and five were conducted in other countries.
The literature on sex differences in co-occurring anxiety or mood disorders and ASD is mixed and dependent on cognitive abilities. In some studies, females with high functioning autism were at greater risk for internalizing psychopathology than both male children with ASD and typically developing female children (Solomon et al., 2012; Mandy et al., 2012). These studies are supported by a Finnish report that found female children with ASD had lower scores on a test associated with major depressive disorder compared to male children with ASD (Mattila et al., 2010). Other studies found no sex differences in the of co-occurrence of anxiety or depression in children with ASD and varying cognitive abilities (Quek et al., 2012; Gadow et al., 2005; Park et al., 2012b; Simonoff et al., 2008; Mayes and Calhoun, 2011; Lai et al., 2011). In the general population, females have more panic attacks, generalized anxiety disorders and males have more social anxiety (American Psychiatric Association, 2013). Based on this review, the current literature is inconclusive on whether a sex difference in children with ASD and co-occurring anxiety or mood disorders exists, although a few studies suggest more anxiety and mood disorders in females than males with ASD.
Schizophrenia
Schizophrenia is a mental disorder that involves delusions, disorganized behavior, disorganized speech, hallucinations, and restrictions in the range and intensity of emotions (American Psychiatric Association, 2013). Schizophrenia typically presents between 18 and 30 years of age with earlier onset associated with male sex. Lifetime prevalence of schizophrenia is near 0.2 % (American Psychiatric Association, 2013) The prevalence of schizophrenia in eight-year olds with ASD is less than 1 % (Levy et al., 2010). Two articles met search criteria and addressed schizophrenia. These two articles were published in 2005 and 2010 and were both case–control studies. Review of the two studies found conflicting results on sex differences and the co-occurrence of ASD and schizophrenia or schizophrenia spectrum traits. A parental survey of 6 to 12 year olds with ASD found schizophrenia spectrum traits to be twice as prevalent in females compared to males (57 %: 28 %) independent of ID (Gadow and DeVincent, 2012). Conversely, in a group of 6 to 12 year olds with ASD and ID, schizophrenia was more common in males than females (Tsakanikos et al., 2011). Again, the literature is relatively sparse due to the late onset of schizophrenia and the rarity of co-occurring schizophrenia: future research is warranted.
Medical Domain
Birth defects/Chromosomal Disorders /Genetic Disorders
Population-based surveillance data from the 2008 ADDM report found that among children with ASD, less than 1 % had a co-occurrence of fragile X syndrome, Down syndrome, chromosomal disorders, or other genetic and congenital diagnoses (Levy et al., 2010). It is likely that these rates are under-reported because investigation of ASD co-occurring conditions was not the focus of the ADDM surveillance effort. However, a cohort study of children in Georgia found a similar prevalence of chromosomal disorders and Down syndrome in persons with ASD (Schendel et al., 2009).
There were four studies reviewed that met search criteria and addressed ASD sex differences in birth defects, chromosomal disorders, and genetic disorders: two systematic reviews, one case–control study, and one surveillance study. Co-occurring birth defects, such as impairments to the central nervous system, cardiovascular system, genitourinary system, or musculoskeletal system, appear more often in males than females with ASD. Among children with ASD, the male to female ratio was 9:1 if a child had a co-occurring birth defect and 3.6:1 if the child did not have a co-occurring birth defect (Schendel et al., 2009).
A review conducted by Reilly (2009) found that males with ASD have more co-occurring Down syndrome than females with ASD and the male to female ratio among children with both ASD and Down syndrome may be near the overall ASD prevalence ratio of 4:1. A review conducted by Wiznitzer (2004) found no difference between males and females with ASD and the co-occurrence of tuberous sclerosis. Clifford et al. (2007) found that about 70 % of males aged 5 to 80 with fragile X syndrome had co-occurring ASD while 23 % of females in the same age range with fragile X had co-occurring ASD. The difference in co-occurrence of ASD between males and females may suggest a greater association between the two conditions in males as compared to females.
It is important to note that birth defects, chromosomal disorders, and genetic disorders are rare and seldom studied. Therefore, the results on sex differences for co-occurring ASD and chromosomal and genetic conditions are inconclusive.
Head Size / Encephalopathy
Head size, specifically an enlarged head circumference or macrocephaly, has been associated with ASD (Wallace and Treffert, 2004). Three articles were reviewed that examined differences in head size between males and females with ASD. Studies include two case–control studies and one cross-sectional study. Two studies were conducted in the US and one study was conducted in Italy. A cross-sectional study by Fombonne et al. (1999) found no difference in head size between males and females aged 2 to 16 with ASD. Sacco et al. (2007) also found no difference in head size between males and females aged 3 to 16 with ASD. In contrast, Aylward et al. (2002) found larger head sizes in male adults and children compared to female adults and children with ASD, but the female sample size was low (n=9).
Abnormal Eating and Gastrointestinal Issues
In a population-based study conducted by Nicholas et al. (2008), about 54 % of children with ASD had an abnormality in eating, drinking, or sleeping, which is nearly 40 % higher than that of children with at least one symptom of ASD but no diagnosis (Nicholas et al., 2008). Some studies have shown an increase in certain gastrointestinal symptoms among persons with ASD, including constipation (Ibrahim et al., 2009) and diarrhea (Wang et al., 2006), while other studies found no significant increase in overall gastrointestinal symptoms or symptoms such as esophageal reflux, vomiting, and abdominal discomfort (Ibrahim et al., 2009; Wang et al., 2006; Valicenti-McDermott et al., 2007). However, little research on gastrointestinal issues has been conducted at a population level and no studies were found that compared males to females on gastrointestinal response. More research is needed to determine if there is an association between gastrointestinal symptoms and ASD and whether the association differs between the sexes.
Four studies were found that compared the sexes and addressed food selectivity. These four studies were conducted in the United States between 2006 and 2010 and included one case–control and three cross-sectional designs. In general, review of these studies found food selectivity and feeding issues to be more frequent in children with ASD than children without ASD (Valicenti-McDermott et al., 2007; Ibrahim et al., 2009), although limited research is available in this area. There was no difference between child sexes in over or under-eating in a study of children with high functioning autism (Worley and Matson, 2011) and no differences between the sexes in eating abnormalities in two studies conducted in children with ASD and varying cognitive abilities (Mayes and Calhoun, 2011; Horovitz et al., 2011). Based on this limited review, it appears unlikely that there is a difference in eating habits between males and females with ASD.
Seizures/ Epilepsy
Epilepsy and other seizure disorders co-occur in 5 % to 40 % of children with ASD and there is differential prevalence based on ID (Baird et al., 2008; Nicholas et al., 2008). This review found three articles that met search criteria and addressed seizures or epilepsy. These three articles were published between 2008 and 2013 and consist of a cohort study, one cross-sectional study, and one meta-analysis. Females with ASD were found to have more epilepsy than males with ASD; the male to female ratio drops to near 2:1 in children with ASD and co-occurring epilepsy, but this may be partly due to differential ID (Amiet et al., 2008; Bolton et al., 2011; Ben-Itzchak et al., 2013). There may be an increased likeliness in females with ASD to have co-occurring epilepsy or seizure disorder; however, the literature is sparse so a conclusion cannot be drawn. Further research is needed to enhance current knowledge of sex differences in children with ASD and epilepsy or seizure disorder.
Sleep Disturbances
In a systematic review of parental sleep surveys, sleep problems were present in 50 % to 80 % of children with ASD compared to 9 % to 50 % in matched typically developing children (Kotagal and Broomall, 2012). There were six articles reviewed that met search criteria and addressed sleep disturbances. These six articles were published between 2004 and 2012 and included two case–control studies, two cohort studies, and two cross-sectional studies. Four were conducted in the United States and three were conducted in other countries. Based on this review, some studies found no sex differences in sleep problems among persons with ASD (Liu et al., 2006; Wiggs and Stores, 2004; Mayes and Calhoun, 2011; Horovitz et al., 2011), one study found that female children with ASD have less sleep problems than male children with ASD (Sivertsen et al., 2012), and one study found female children with ASD have more sleep problems than male children with ASD (Hartley and Sikora, 2009). The minimal amount of research in this area leads to inconsistent results and prevents definitive conclusions on whether a sex difference exists in sleep disturbance.

Vaccine News – Study – INFANTS RECEIVING MERCURY-CONTAINING VACCINES DEVELOPED SPEECH DISORDERS, SLEEP DISORDERS, AND AUTISM, ACCORDING TO CDC SCIENTISTS

Dr. Andrew Moulden: Every Vaccine Produces Harm
by John P. Thomas
Health Impact News
Canadian physician Dr. Andrew Moulden provided clear scientific evidence to prove that every dose of vaccine given to a child or an adult produces harm. The truth that he uncovered was rejected by the conventional medical system and the pharmaceutical industry. Nevertheless, his warning and his message to America remains as a solid legacy of the man who stood up against big pharma and their program to vaccinate every person on the Earth.
Dr Moulden died unexpectedly in November of 2013 at age 49.
Because of the strong opposition from big pharma concerning Dr. Moulden’s research, I became concerned that the name of this brilliant researcher and his life’s work had nearly been deleted from the internet. His reputation was being disparaged, and his message of warning and hope was being distorted and buried without a tombstone.
I prepared a series of articles as a tribute to a great physician and as a memorial to a courageous individual who was not afraid to speak the truth about medical corruption and a flawed healthcare system that does more to harm health than it does to cure disease.
This is the first in a series of four articles about Dr. Moulden — the man, the physician, and the powerful advocate for ending all vaccine use. In future articles, I will summarize his detailed scientific evidence, which shows how vaccine damage occurs. I will explain the common mechanisms behind vaccine damage and how vaccines harm the health of everyone who receives them regardless of whether or not they notice any adverse reactions at the time they take the shots.
Dr. Moulden stated:
What we have done to each other [with vaccines] has produced the most profound damage to humankind by humankind in the history of humanity. And the reason why we got here is partly because of:
Our arrogance in thinking that we know everything. In physiology and medicine we do not know everything!
[Our greed] to advance our own self-interest to make money, to sell products and to advance corporate alliances. Commercialization has overtaken the fundamental human value of “do unto others as you would have others do unto you.” When society turns toward this human value, then we would all be working together for the greater good of each other. [However, other values have become more important] I don’t care whose feet I step on or how I get there as long as my American dream is realized. I don’t care who has to pay for it on the way of getting there. [1]
Dr. Moulden’s Credibility
Was Dr. Moulden a crackpot as some sources claim, or was he a brilliant physician and researcher? This series of articles will set the record straight, and summarize the contribution that his work has made to medical knowledge.
When I evaluate the credibility of people who are unknown to me, I begin by seeking answers to a few basic questions. For example: Is this person offering opinion, or can he or she back up the claims with valid science? Does he have educational credentials? Are there other physicians and scientists who support his or her beliefs and recommendations? Is this person controlled by the pharmaceutical industry, allopathic medical associations, or the US FDA (US Food and Drug Administration)? And finally, what do Quackwatch and their friends have to say about the person?
Dr. Moulden had a PhD in Clinical Psychology and Neuropsychology. He had a master’s degree in child development, and was also a medical doctor. [2] His work was respected by other researchers who don’t march to the drumbeat of the pharmaceutical companies. Dr. Moulden was a threat to the pharmaceutical industry, and their Quackwatch family of 21 related websites treated him as an enemy. [3, 4]

Vaccine Contraindications: Six People Who Should Not Be Vaccinated
The debate surrounding vaccinations is a fierce one, and personally, I don’t like to argue about it. I’m happy to make the right choices for my family while you make the right ones for yours. (I personally have suffered adverse reactions to vaccinations.) It’s ok to have different opinions, really it is. But there are a lot of folks out there who think everyone should be vaccinated, period, and those who choose not to vaccinate should be penalized or worse.
Listen. I get that people are scared and there’s a lot of fear-mongering in the media. But let’s be realistic here: vaccinations are a medical procedure. There are risks. Vaccinations are not right for everyone. There are at least six types of people in particular who should avoid vaccinations, and below, I’ll spell it out.
Vaccine Contraindications
Just like a particular surgery or prescription medication won’t work well for everyone, vaccinations are not a good choice for everyone.
Some people, in particular, are much more likely to have adverse reactions to vaccinations, including:

– Those with an autoimmune disease
– Children born to a mother with an autoimmune disease
– Anyone who is sick
– Pregnant women
– Those who have previously had a reaction to a vaccination

One size does not fit all
Clearly, vaccinations are not the right choice for everyone, and each family should decide what is right for them and their children. When parents are aware of vaccine contraindications, they can make informed and safer choices for their children.
Please share this post so that other parents can learn about vaccine contraindications and decide if vaccination is right for their children.

USA: Highest Vaccination Rate in the World Has the Worst Health
by PAUL FASSA
That “worst health” label includes a ranking of 34th in the world with infant mortality. In other words, the USA has the 34th worst infant survival with its highest rate of vaccinations. Some are directly from multiple vaccinations administered.
But the USA leads the world in infant vaccinations, those administered during the first year after their births – 26 vaccinations during that time.
The only vaccination I recall receiving during early childhood, circa 1948, was the smallpox vaccine, the one that left a circle of shallow pockmarks on the upper arm, a non-ink tattoo that proved you had received that vaccine. Months later there was the booster shot which gave me a vacation of several days away from my first grade teacher while sitting out the chicken pox.
During Naval training the mass vaccination high pressure hand held gun that replaced syringes and needles was tried on us with the polio shot. I wound up with a vacation in the base infirmary with an extended period of the flu. Between those two, there may have been a tetanus shot or two.
From the Healthy Home Economist:

-In1950, there were 3 childhood vaccines typically given when a child entered school.
-In 1983, there were 10 recommended vaccines by the age of 6 years old (24 doses, 7 injections, 4 oral doses for polio).
-In 2010, the CDC vax schedule totaled 68 doses with more than half given by the time a child was only a year and a half old.
-In 2016, the schedule has increased to 74 doses by age 17 with 53 injections and 3 oral doses of rotavirus.

The number of vaccines included in the current childhood vaccine schedule has quadrupled over the past 60 years, with several demanding multiple injections and boosters. During this exponential rise of CDC “recommended” schedules, the health of American children has plummeted.
Autoimmune diseases, learning disabilities, food allergies, chronic ailments, and childhood obesity have all risen. The overall health of this nation ranks very low compared to all other industrialized nations, dead last in most areas.
Vaccine false dogma is so heavy hardly anyone with authority, even in mainstream media, makes the connection between poor health with high vaccination rates. Instead, more, three added for 2016, are getting enforced by mandate or coerced by pediatricians who have the right to refuse medical care on kids who aren’t vaccinated.
Destroying Health with Vaccines is Good Business

50 Studies the AAP Avoided to Mention
There is a robust, worldwide body of published science from highly esteemed scientists questioning the safety of many different aspects of vaccines-how come we never hear from them? The majority of the most compelling science has been published since 2010. Below find 50 such studies to consider, sorted chronologically, and note that these studies only represent a portion of the published work implicating vaccinations in a wide variety of negative health outcomes.
The American Academy of Pediatrics made representations to President Trump in a letter dated 2/7/2017 that are utterly indefensible and inaccurate, as any rational review of the studies below quickly demonstrates. For example, the AAP wrote:
“Claims that vaccines are unsafe when administered according to expert recommendations have been disproven by a robust body of medical literature…we write to express our unequivocal support for the safety of vaccines.”
We contend that the AAP’s statements to the President are baseless, reckless, and easily refuted. The AAP’s letter alone supports the President’s desire to field a Vaccine Safety Commission and do all we can to make vaccines as safe as possible. Please click here for a list of all 50 studies detailed below.

2017
Temporal Association of Certain Neuropsychiatric Disorders Following Vaccination of Children and Adolescents A Pilot Case–Control Study
New Quality-Control Investigations on Vaccines Micro-and Nanocontamination
2016
Behavioral abnormalities in female mice following administration of aluminum adjuvants and the human papillomavirus (HPV) vaccine Gardasil
Autoimmune/Inflammatory Syndrome Induced by Adjuvants and Sjogren’s Syndrome
Combining Childhood Vaccines at One Visit Is Not Safe
Aluminum in Childhood Vaccines Is Unsafe
Aluminium in brain tissue in familial Alzheimer’s disease
2015
Evidence that Food Proteins in Vaccines Cause the Development of Food Allergies and Its Implications for Vaccine Policy
2014
Transcriptomic Analyses of Neurotoxic Effects in Mouse Brain After Intermittent Neonatal Administration of Thimerosal
A Dose-Response Relationship between Organic Mercury Exposure from Thimerosal-Containing Vaccines and Neurodevelopmental Disorders
A comparison of temporal trends in United States autism prevalence to trends in suspected environmental factors
2013
A Population-Based Cohort Study of Undervaccination in 8 Managed Care Organizations Across the United States
Autoimmune/inflammatory syndrome induced by adjuvants (ASIA) 2013: Unveiling the pathogenic, clinical and diagnostic aspects
Aluminum in the central nervous system (CNS): toxicity in humans and animals, vaccine adjuvants, and autoimmunity
Autoimmune/inflammatory syndrome induced by adjuvants (Shoenfeld’s syndrome): clinical and immunological spectrum
A two-phase study evaluating the relationship between Thimerosal-containing vaccine administration and the risk for an autism spectrum disorder diagnosis in the United States
Human exposure to aluminium
Human Papilloma Virus Vaccine and Primary Ovarian Failure: Another Facet of the Autoimmune/Inflammatory Syndrome Induced by Adjuvants
2012
Risk of Febrile Seizures and Epilepsy After Vaccination With Diphtheria, Tetanus, Acellular Pertussis, Inactivated Poliovirus, and Haemophilus Influenzae Type b
Mechanisms of aluminum adjuvant toxicity and autoimmunity in pediatric populations
Neurologic adverse events following vaccination
The spectrum of ASIA: ‘Autoimmune (Auto-inflammatory) Syndrome induced by Adjuvants’
Relative trends in hospitalizations and mortality among infants by the number of vaccine doses and age, based on the Vaccine Adverse Event Reporting System (VAERS), 1990-2010
2011
Do aluminum vaccine adjuvants contribute to the rising prevalence of autism?
Maternal Thimerosal Exposure Results in Aberrant Cerebellar Oxidative Stress, Thyroid Hormone Metabolism, and Motor Behavior in Rat Pups; Sex- and Strain-Dependent Effects
2010
Interindividual variations in the efficacy and toxicity of vaccines
Sorting out the spinning of autism: heavy metals and the question of incidence
Influence of pediatric vaccines on amygdala growth and opioid ligand binding in rhesus macaque infants: A pilot study
The immunobiology of aluminium adjuvants: how do they really work?
Hepatitis B Vaccination of Male Neonates and Autism Diagnosis, NHIS 1997-2002
2009
Allergic Disease and Atopic Sensitization in Children in Relation to Measles Vaccination and Measles Infection
Long-term persistence of vaccine-derived aluminum hydroxide is associated with chronic cognitive dysfunction
Delayed acquisition of neonatal reflexes in newborn primates receiving a thimerosal-containing Hepatitis B vaccine: Influence of gestational age and birth weight
Aluminum hydroxide injections lead to motor deficits and motor neuron degeneration
2008
Post-vaccination encephalomyelitis: Literature review and illustrative case
Thimerosal exposure in infants and neurodevelopmental disorders: An assessment of computerized medical records in the Vaccine Safety Datalink
Delay in diphtheria, pertussis, tetanus vaccination is associated with a reduced risk of childhood asthma?
Hepatitis B triple series vaccine and developmental disability in US children aged 1-9 years
2005
THE MERCURY USED AS A VACCINE PRESERVATIVE IS FAR MORE NEUROTOXIC THAN THE MERCURY FOUND IN FISH
Comparison of Blood and Brain Mercury Levels in Infant Monkeys Exposed to Methylmercury or Vaccines Containing Thimerosal
Thimerosal Neurotoxicity is Associated with Glutathione Depletion: Protection with Glutathione Precursors
2004
Activation of methionine synthase by insulin-like growth factor-1 and dopamine: a target for neurodevelopmental toxins and thimerosal
2002
UTAH STATE SCIENTISTS FIND AUTOIMMUNE REACTION TO MMR IN CHILDREN WITH AUTISM, INCLUDING AUTOIMMUNITY TO MYELIN BASIC PROTEIN, A BRAIN BUILDING-BLOCK
Abnormal Measles-Mumps-Rubella Antibodies and CNS Autoimmunity in Children with Autism
2001
Macrophagic myofasciitis lesions assess long-term persistence of vaccine derived aluminum hydroxide in muscle
2000
JAPANESE SCIENTISTS FIND VACCINE-STRAIN OF MEASLES IN THE GUTS OF CHILDREN WITH AUTISM
Detection and Sequencing of Measles Virus from Peripheral Mononuclear Cells from Patients with Inflammatory Bowel Disease and Autism
CDC SCIENTISTS ADMIT THAT 90% OF INFECTIOUS DISEASE MORTALITY DECREASE IN THE UNITED STATES HAPPENED BEFORE VACCINES WERE AVAILABLE
Annual Summary of Vital Statistics: Trends in the Health of Americans During the 20th Century
Iatrogenic exposure to mercury after hepatitis B vaccination in preterm infants
Effects of Diphtheria-Tetanus-Pertussis or Tetanus Vaccination on Allergies and Allergy-Related Respiratory Symptoms Among Children and Adolescents in the United States
1999
INFANTS RECEIVING MERCURY-CONTAINING VACCINES DEVELOPED SPEECH DISORDERS, SLEEP DISORDERS, AND AUTISM, ACCORDING TO CDC SCIENTISTS
Increased risk of developmental neurologic impairment after high exposure to thimerosal-containing vaccine in first month of life
INFECTIOUS DISEASE RATES DECLINED PRECIPITOUSLY IN THE UNITED STATES IN THE 20TH CENTURY BEFORE THE IMPLEMENTATION OF A NATIONAL VACCINE PROGRAM
Trends in Infectious Disease Mortality in the United States During the 20th Century
CDC SCIENTISTS FIND CHILDREN GIVEN THE MMR VACCINE SHED THE MEASLES VIRUS FOR AT LEAST 2 WEEKS AFTER GETTING THE VACCINE, MAKING THEM VECTORS TO SPREAD MEASLES
Detection of Measles Virus RNA in Urine Specimens from Vaccine Recipients

Autism related studies

Autism related studies
Fever plus mitochondrial disease could be risk factors for autistic regression.

Abstract
Autistic spectrum disorders encompass etiologically heterogeneous persons, with many genetic causes. A subgroup of these individuals has mitochondrial disease. Because a variety of metabolic disorders, including mitochondrial disease show regression with fever, a retrospective chart review was performed and identified 28 patients who met diagnostic criteria for autistic spectrum disorders and mitochondrial disease. Autistic regression occurred in 60.7% (17 of 28), a statistically significant increase over the general autistic spectrum disorder population (P < .0001). Of the 17 individuals with autistic regression, 70.6% (12 of 17) regressed with fever and 29.4% (5 of 17) regressed without identifiable linkage to fever or vaccinations. None showed regression with vaccination unless a febrile response was present. Although the study is small, a subgroup of patients with mitochondrial disease may be at risk of autistic regression with fever. Although recommended vaccinations schedules are appropriate in mitochondrial disease, fever management appears important for decreasing regression risk.

Is fever a predictive factor in the autism spectrum disorders?

If it is confirmed that autistic children with high fevers are of higher functionality, it is possible for preventive intervention programs to be developed where children are exposed to the least possible chemical drugs intervention (antipyretics, antibiotics, etc.) or even selective vaccination. Further experimental, epidemiological and clinical studies are necessary to investigate the above.

Prevalence of autism spectrum disorders–Autism and Developmental Disabilities Monitoring Network, 14 sites, United States, 2008.

RESULTS:
For 2008, the overall estimated prevalence of ASDs among the 14 ADDM sites was 11.3 per 1,000 (one in 88) children aged 8 years who were living in these communities during 2008. Overall ASD prevalence estimates varied widely across all sites (range: 4.8-21.2 per 1,000 children aged 8 years). ASD prevalence estimates also varied widely by sex and by racial/ethnic group. Approximately one in 54 boys and one in 252 girls living in the ADDM Network communities were identified as having ASDs. Comparison of 2008 findings with those for earlier surveillance years indicated an increase in estimated ASD prevalence of 23% when the 2008 data were compared with the data for 2006 (from 9.0 per 1,000 children aged 8 years in 2006 to 11.0 in 2008 for the 11 sites that provided data for both surveillance years) and an estimated increase of 78% when the 2008 data were compared with the data for 2002 (from 6.4 per 1,000 children aged 8 years in 2002 to 11.4 in 2008 for the 13 sites that provided data for both surveillance years). Because the ADDM Network sites do not make up a nationally representative sample, these combined prevalence estimates should not be generalized to the United States as a whole.

Bactericidal Antibiotics Induce Mitochondrial Dysfunction and Oxidative Damage in Mammalian Cells

Abstract
Prolonged antibiotic treatment can lead to detrimental side effects in patients, including ototoxicity, nephrotoxicity, and tendinopathy, yet the mechanisms underlying the effects of antibiotics in mammalian systems remain unclear. It has been suggested that bactericidal antibiotics induce the formation of toxic reactive oxygen species (ROS) in bacteria. We show that clinically relevant doses of bactericidal antibiotics—quinolones, aminoglycosides, and β-lactams—cause mitochondrial dysfunction and ROS overproduction in mammalian cells. We demonstrate that these bactericidal antibiotic–induced effects lead to oxidative damage to DNA, proteins, and membrane lipids. Mice treated with bactericidal antibiotics exhibited elevated oxidative stress markers in the blood, oxidative tissue damage, and up-regulated expression of key genes involved in antioxidant defense mechanisms, which points to the potential physiological relevance of these antibiotic effects. The deleterious effects of bactericidal antibiotics were alleviated in cell culture and in mice by the administration of the antioxidant N-acetyl-L-cysteine or prevented by preferential use of bacteriostatic antibiotics. This work highlights the role of antibiotics in the production of oxidative tissue damage in mammalian cells and presents strategies to mitigate or prevent the resulting damage, with the goal of improving the safety of antibiotic treatment in people.

Medical journal says fluoride is in same toxin category as brain-damaging lead and mercury

Neurobehavioural effects of developmental toxicity

Summary

Neurodevelopmental disabilities, including autism, attention-deficit hyperactivity disorder, dyslexia, and other cognitive impairments, affect millions of children worldwide, and some diagnoses seem to be increasing in frequency. Industrial chemicals that injure the developing brain are among the known causes for this rise in prevalence. In 2006, we did a systematic review and identified five industrial chemicals as developmental neurotoxicants: lead, methylmercury, polychlorinated biphenyls, arsenic, and toluene. Since 2006, epidemiological studies have documented six additional developmental neurotoxicants—manganese, fluoride, chlorpyrifos, dichlorodiphenyltrichloroethane, tetrachloroethylene, and the polybrominated diphenyl ethers. We postulate that even more neurotoxicants remain undiscovered. To control the pandemic of developmental neurotoxicity, we propose a global prevention strategy. Untested chemicals should not be presumed to be safe to brain development, and chemicals in existing use and all new chemicals must therefore be tested for developmental neurotoxicity. To coordinate these efforts and to accelerate translation of science into prevention, we propose the urgent formation of a new international clearinghouse.

Read more at:

http://www.thelancet.com/journals/laneur/article/PIIS1474-4422%2813%2970278-3/fulltext#article_upsell

http://www.thelancet.com/pdfs/journals/laneur/PIIS1474-4422(13)70278-3.pdf

Autism, developmental delays linked to pesticide exposure during pregnancy – study

Autism, developmental delays linked to pesticide exposure during pregnancy – study

Exposure to several common agricultural pesticides during pregnancy increases the risk of developmental delays and autism in children by two-thirds, a new study found. While researchers did not say pesticides cause autism, a direct link is plausible.

Researchers at the University of California, Davis’ MIND Institute tracked associations with specific classes of pesticides (including organophosphates, pyrethroids and carbamates) and later diagnoses of autism and developmental delay in children. They used maps from the California Pesticide Use Report (1997-2008) and the addresses of expectant mothers to track women’s exposure to agricultural pesticide spraying during their pregnancies.

Developmental delay, in which children take extra time to reach communication, social or motor skills milestones, affects about four percent of US. kids, the authors wrote. The Centers for Disease Control and Prevention estimates that one in 68 children has an autism spectrum disorder (ASD), also marked by deficits in social interaction and language.

Of the 970 children covered by the study, 486 had an ASD, 168 had developmental delays and 316 had typical development.

“We mapped where our study participants’ lived during pregnancy and around the time of birth. In California, pesticide applicators must report what they’re applying, where they’re applying it, dates when the applications were made and how much was applied,” principal investigator Irva Hertz-Picciotto, a MIND Institute researcher and professor and vice chair of the Department of Public Health Sciences at UC Davis, said in a statement. “What we saw were several classes of pesticides more commonly applied near residences of mothers whose children developed autism or had delayed cognitive or other skills.”

 

More at:

http://rt.com/usa/167976-autism-gestational-pesticide-exposure/