The Lancet – Community transmission and viral load kinetics of the SARS-CoV-2 delta (B.1.617.2) variant in vaccinated and unvaccinated individuals in the UK: a prospective, longitudinal, cohort study

Covid vaccinations ‘not sufficient’ in preventing Delta variant spread, almost equal to unvaccinated – UK study

Source: https://www.thelancet.com/journals/laninf/article/PIIS1473-3099(21)00648-4/fulltext

PDF: https://www.thelancet.com/action/showPdf?pii=S1473-3099%2821%2900648-4

Interpretation

Vaccination reduces the risk of delta variant infection and accelerates viral clearance. Nonetheless, fully
vaccinated individuals with breakthrough infections have peak viral load similar to unvaccinated cases and can
efficiently transmit infection in household settings, including to fully vaccinated contacts. Host–virus interactions
early in infection may shape the entire viral trajectory.

Summary
Background The SARS-CoV-2 delta (B.1.617.2) variant is highly transmissible and spreading globally, including in
populations with high vaccination rates. We aimed to investigate transmission and viral load kinetics in vaccinated
and unvaccinated individuals with mild delta variant infection in the community.
Methods Between Sept 13, 2020, and Sept 15, 2021, 602 community contacts (identified via the UK contract-tracing
system) of 471 UK COVID-19 index cases were recruited to the Assessment of Transmission and Contagiousness of
COVID-19 in Contacts cohort study and contributed 8145 upper respiratory tract samples from daily sampling for up
to 20 days. Household and non-household exposed contacts aged 5 years or older were eligible for recruitment if they
could provide informed consent and agree to self-swabbing of the upper respiratory tract. We analysed transmission
risk by vaccination status for 231 contacts exposed to 162 epidemiologically linked delta variant-infected index cases.
We compared viral load trajectories from fully vaccinated individuals with delta infection (n=29) with unvaccinated
individuals with delta (n=16), alpha (B.1.1.7; n=39), and pre-alpha (n=49) infections. Primary outcomes for the
epidemiological analysis were to assess the secondary attack rate (SAR) in household contacts stratified by contact
vaccination status and the index cases’ vaccination status. Primary outcomes for the viral load kinetics analysis were
to detect differences in the peak viral load, viral growth rate, and viral decline rate between participants according to
SARS-CoV-2 variant and vaccination status.
Findings

The SAR in household contacts exposed to the delta variant was 25% (95% CI 18–33) for fully vaccinated
individuals compared with 38% (24–53) in unvaccinated individuals. The median time between second vaccine dose and
study recruitment in fully vaccinated contacts was longer for infected individuals (median 101 days [IQR 74–120]) than
for uninfected individuals (64 days [32–97], p=0·001). SAR among household contacts exposed to fully vaccinated index
cases was similar to household contacts exposed to unvaccinated index cases (25% [95% CI 15–35] for vaccinated vs 23%
[15–31] for unvaccinated). 12 (39%) of 31 infections in fully vaccinated household contacts arose from fully vaccinated
epidemiologically linked index cases, further confirmed by genomic and virological analysis in three index case–contact
pairs. Although peak viral load did not differ by vaccination status or variant type, it increased modestly with age
(difference of 0·39 [95% credible interval –0·03 to 0·79] in peak log10 viral load per mL between those aged 10 years and
50 years). Fully vaccinated individuals with delta variant infection had a faster (posterior probability >0·84) mean rate of
viral load decline (0·95 log10 copies per mL per day) than did unvaccinated individuals with pre-alpha (0·69), alpha (0·82),
or delta (0·79) variant infections. Within individuals, faster viral load growth was correlated with higher peak viral load
(correlation 0·42 [95% credible interval 0·13 to 0·65]) and slower decline (–0·44 [–0·67 to –0·18]).

Vaccine News – MILLIONS OF ITALIANS PROTEST NEWLY PROPOSED VACCINE MANDATE

✴️ Stop what you’re doing and see this now! MILLIONS are protesting in non-stop demonstrations all across Italy! They’re not only fighting for their own children, they’re fighting to MAKE SURE these heinous laws do not pass in other countries. UNITY is an unstoppable force! Still think vaccines are safe? Check this out while it’s still playing! tinyurl.com/9Episodes <<< Revisions to the Italian mandate have already been made thanks to these protests, yet Italy will NOT QUIT until there are no tyrannical mandates at ALL!
✴️ Networking, exemption information and doctor resources: tinyurl.com/RevolutionForVaccineChoice
✴️ Follow us: facebook.com/RevolutionForChoice
✴️ Read all vaccine inserts: tinyurl.com/ReadTheVaccineInsert
#RevolutionForChoice #InformedConsent #EducateBeforeYouVaccinate #VAXXED #Italy #Unity #NonCompliance #SB277 #Freedom

Co-Author of Lancet MMR-Autism Study Exonerated on All Charges of Professional Misconduct
Dr. John Walker-Smith, considered the father of pediatric gastroenterology, has today been restored to his much-deserved reputation of high esteem. His appeal of the U.K. General Medical Council’s 2010 decision to remove his license for serious professional misconduct has been quashed in its entirety. This decision raises questions about the validity of the 2010 GMC proceeding in general.
The GMC proceeding was a multi-year, multi-million dollar prosecution against Drs. Wakefield, Walker-Smith, and Murch. It related to a controversial 1998 study published in The Lancet suggesting a possible link between autism, the measles-mumps-rubella vaccine and bowel disease. Based on the GMC prosecution, both Drs. Walker-Smith and Wakefield lost their licenses to practice and the Lancet article was officially retracted. The GMC alleged that the physician-authors had failed to obtain necessary ethical clearances and that they had subjected the twelve children in the study to unnecessary medical procedures.
Justice Mitting, reviewing Dr. Walker-Smith’s appeal in the High Court of Justice, Queen’s Bench Division, Administrative Court, found that the GMC’s conclusions were “based on inadequate and superficial reasoning” and that “the finding of serious professional misconduct and the sanction of erasure are both quashed.”
See full text of the decision

Repeal Immunity for Drug Companies Against Vaccine Injuries
Why should the drug companies be above the law? If vaccines are safe, there would be no need to grant the drug companies immunity. In 1986 Congress gave the drug companies immunity against all lawsuits from vaccine related injuries. The Federal Government is now paying out billions in damages to some parents whose children have been hurt by vaccines. While the drug companies continue to rack up huge profits, most families continue to pay for the damages with their own money.

Robert F. Kennedy, Jr.: Doing the math on meningitis vaccinations
By Robert F. Kennedy, Jr.
Posted: 06/09/2015 07:55:00 PM MDT
This past Thursday, the University of Colorado-Boulder student government passed a resolution asking the CDC’s Advisory Committee on Immunization Practices (ACIP) to recommend meningococcal vaccines for all incoming college students. ACIP will consider CU-Boulder’s resolution on June 24. ACIP’s first agenda topic will be the debate over recommending the meningococcal B vaccines for adolescents and college students.
With billions of dollars in annual revenue at stake, vaccine makers are pushing meningitis vaccine mandates across the country. Vaccine issues are always complex, but advocates of the meningitis mandate should consider some simple math.
Meningococcal meningitis is exceedingly rare. There were only about 390 cases in the U.S. last year. In a population of 319 million, that adds up to one case in 817,949 people. There were only three meningococcal meningitis cases in Colorado last year — one resulting in death. The CDC has approved three vaccines targeting the A, C, Y and W135 strains of meningitis: Menactra, Menveo and Menomune, which still contains significant mercury concentrations in multi-dose vials. These vaccines are effective in providing immunity to those strains of meningitis in only 85 percent of people who receive them.
Thirty percent of the meningitis cases are the B strain, which typically occur in college-aged kids and against which the three vaccines are completely ineffective.
The FDA recently approved two B strain meningococcal vaccines, Trumenba and Bexsero.Vaccine makers are pushing government officials to add them to the recommended schedule for the fall semester. Critics have faulted the government’s expedited safety and efficiency testing for the new B strain vaccines citing glaring lapses in safety protocols including the absence of inactive placebos. In addition, both new B vaccines are “pregnancy category B,” meaning that they should be administered to pregnant women only when necessary. Neither vaccine has been tested for carcinogenicity, mutagenicity or effects on male fertility.
According to their package inserts, Menactra and Menveo produce “serious adverse events” in 1 percent of recipients. Menomune, with its hefty mercury load, sickens 1.3 percent of those receiving it. According to the CDC Pink Book, 0.3 percent of those with “serious adverse events” from meningitis vaccines will die. So here is the math calculation that thoughtful student governments in Colorado must consider: If you inoculate Colorado’s 400,000 college students with the older vaccines, you can expect 4,000 serious adverse events and 12 dead. We do not yet know the effects of widespread vaccination of the hastily-expedited B vaccines, but according to their package inserts, about 2 percent of students who receive the B vaccine will be sickened or hospitalized with a serious adverse event. This could translate into an additional 8,000 sick students and 24 deaths, for a total of 12,000 sick and 36 dead in the attempt to possibly avert three meningitis cases.

Sanjay Gupta MD has to admit ON CNN that a Neurologist’s (yes a doctor’s) daughter’s autism was caused by vaccines.
I think it pains him… He says this is “very rare” in the video. Thoughts?

Pet vaccination

MILLIONS OF ITALIANS PROTEST NEWLY PROPOSED VACCINE MANDATE
For over a month Italians have been protesting in every city against a brutal proposed law that if approved will make 53 doses of vaccines mandatory.

Groundbreaking Study: Vaccines Cause Children More Adverse Reactions Than Any Other Drug
April 26, 2014

Story at-a-glance
Groundbreaking new study identifies vaccines as the most common source of adverse drug reactions in children, including anaphylaxis and death
Study reveals adverse drug reactions are more common for boys than girls, and infants are the most susceptible age group
Vaccines provide only artificial, temporary, typically inferior immunity compared to what your body receives from natural exposure to a disease
History offers little evidence that vaccines are responsible for eradicating disease even when “herd immunity” vaccination levels have been reached
After vaccines are introduced, new and more virulent strains tend to emerge, suggesting the entire vaccine-immunity paradigm is fatally flawed
By Dr. Mercola
A groundbreaking new drug safety study in Shanghai, China, provides some much needed information about the frequency of vaccine drug reactions among children.
Adverse drug reactions are a serious public health concern and one of the leading causes of morbidity and mortality worldwide.1 More than a half million children are treated every year for adverse drug reactions in US outpatient clinics and emergency rooms.2
The Shanghai study, based on reported pediatric adverse drug reactions (ADRs) for 2009, found that 42 percent were caused by vaccines, with reactions ranging from mild skin rashes to deadly reactions like anaphylaxis and death. Of all the drugs causing adverse reactions among children, vaccines are the most commonly reported.3, 4
This study is particularly significant because the vast majority of reports came from physicians, pharmacists, and other health care providers. Less than three percent of the reports were from consumers.
Another safety report5 about pediatric drug reactions was just published by the Institute for Safe Medication Practices (ISMP) and lists the top 15 drugs causing serious adverse reactions in children.
Psychiatric drugs and analgesics (especially ibuprofen) figure prominently in their top 15 list. The report also mentions psychological side effects such as aggression and suicidal ideation as frequent symptoms from 10 of the 15 most commonly reported drugs.

The Price of Prevention: Vaccine Costs Are Soaring
By ELISABETH ROSENTHALJULY 2, 2014
SAN ANTONIO — There is little that Dr. Lindsay Irvin has not done for the children’s vaccines in her office refrigerator: She remortgaged her home to afford their rising prices. She packed them in ice chests and moved them when her office flooded this year. She pays a company to monitor the fridge in case the temperature rises.
“The security company can call me any time of the day or night so I can go save my vaccines,” said Dr. Irvin, a pediatrician. Those in the refrigerator recently cost $70,000, she said — “more than I paid for four years of medical school.”
Vaccination prices have gone from single digits to sometimes triple digits in the last two decades, creating dilemmas for doctors and their patients as well as straining public health budgets. Here in San Antonio and elsewhere, some doctors have stopped offering immunizations because they say they cannot afford to buy these potentially lifesaving preventive treatments that insurers often reimburse poorly, sometimes even at a loss.
Childhood immunizations are so vital to public health that the Affordable Care Act mandates their coverage at no out-of-pocket cost and they are generally required for school entry. Once a loss leader for manufacturers, because they are often more expensive to produce than conventional drugs, vaccines now can be very profitable.
Old vaccines have been reformulated with higher costs. New ones have entered the market at once-unthinkable prices. Together, since 1986, they have pushed up the average cost to fully vaccinate a child with private insurance to the age of 18 to $2,192 from $100, according to data from the Centers for Disease Control and Prevention. Even with deep discounts, the costs for the federal government, which buys half of all vaccines for the nation’s children, have increased 15-fold during that period. The most expensive shot for young children in Dr. Irvin’s refrigerator is Prevnar 13, which prevents diseases caused by pneumococcal bacteria, from ear infections to pneumonia.

Vaccines may trigger autoimmune diseases
Apr 12, 2015
Anti-vaxxers were severely criticized following the Disneyland measles outbreak, but research shows their reasons for not wanting to vaccinate their children might be well-founded.
Nowadays, newborns are injected with as many as over 30 vaccines before the age of three, but the array of non-ingredients that are found in vaccines have been shown to be unsafe. Yehuda Shoenfeld, also known as the “Godfather of Autoimmunology” is an Israeli clinician who has spent over three decades studying the human immune system. According to a recent article published in the journal Pharmacological Research, the physician joined forces with some of his colleagues and concluded that vaccines [their ingredients, specifically aluminium] represent a significant contributor to the soaring global epidemic of autoimmune diseases. In the article, Dr Shoenfeld and his colleagues issued unprecedented guidelines identifying four categories of people who are most at risk for autoimmunity induced by vaccine.
An autoimmune disorder occurs when the immune system wrongly attacks and destroys healthy body tissue. There are currently over 80 different types of autoimmune disorders. The paper’s authors acknowledge that vaccines prevent infections that can cause autoimmunity, but they also accept conclusions issued by plenty of reports, namely that vaccines can also trigger autoimmunity. Autoimmune diseases which can occur post-vaccination are lupus, arthritis, diabetes mellitus and others, but “almost all types of vaccines have been reported to be associated with the onset of ASIA.”
ASIA is “a wide concept that includes any environmental factor which is demonstrated to trigger autoimmune conditions,” according to Ignasi Rodriguez-Pinto, autoimmunologist at the Barcelona Hospital Clinic. The umbrella term was first identified by Dr Shoenfeld in the Journal of Autoimmunology in 2011 and includes a large spectrum of neurological and immune-mediated phenomena observed following vaccine injections that result from exposure to ingredients such as aluminium. Dr Rodriguez-Pinto pointed out that vaccination for Hepatitis B can also trigger ASIA. The “Grandfather of Autoimmunology” wrote in the paper published in the journal Pharmacological Research that “throughout our lifetime, the normal immune system walks a fine line between preserving normal immune reactions and developing autoimmune diseases.”

Five Year Moratorium on Childhood Vaccines
Created by K.H. on July 03, 2017
American children are in crisis with an explosion of once-rare neurological problems like autism and seizures.
Recent scientific evidence has shown massive contamination of vaccines with unsuspected chemical and biological agents. Other evidence shows dramatic differences in in health outcomes between vaccinated and un-vaccinated children. In order to remedy this we ask the White House to:

ONE: Impose a five year moratorium on all childhood vaccines from birth to age eighteen.
TWO: Repeal the 1986 National Childhood vaccine injury Act and return vaccines to the traditional civil justice system.
THREE: Perform large scale studies of vaccinated and un-vaccinated children.
FOUR: Ban direct pharmaceutical advertising to consumers and allow such advertising only to medical professionals

Can a routine holiday jab send you mad? That’s what BBC reporter Malcolm Brabant says happened to him – and he’s not alone
BBC foreign correspondent Malcolm Brabant had a yellow fever vaccine
24 hours later he had been reduced to a sweating, shivering wreck
Had a fever for two weeks then psychosis: ‘I went completely bonkers’
Spent two years in and out of mental institutions, unable to work
Even attempted suicide, but has fortunately made a full recovery
By Anna Van Praagh For The Daily Mail
Published: 22:21, 6 April 2015 | Updated: 12:31, 7 April 2015

How vaccines are Made, how they work

 

Are fluoride levels in drinking water associated with hypothyroidism prevalence in England?

Are fluoride levels in drinking water associated with hypothyroidism prevalence in England? A large observational study of GP practice data and fluoride levels in drinking water
Findings We found that higher levels of fluoride in drinking water provide a useful contribution for predicting prevalence of hypothyroidism. We found that practices located in the West Midlands (a wholly fluoridated area) are nearly twice as likely to report high hypothyroidism prevalence in comparison to Greater Manchester (non-fluoridated area).

Researchers from the University of Kent, a public research university based in the United Kingdom, conducted the latest and considerably groundbreaking study on the health effects potentially caused by adding fluoride to the public’s water.
After studying data obtained from nearly every medical practice in England, scientists found that fluoride may be increasing the risk for hypothyroidism, or an underactive thyroid, a condition in which the thyroid gland fails to produce enough hormones, resulting in symptoms such as fatigue, obesity and depression.
Published in the Journal of Epidemiology and Community Health, the study included the largest population ever analyzed in relation to the adverse health effects caused by water fluoridation.
Recent UK study includes the “largest population ever studied in regard to adverse effects of elevated fluoride exposure”
After collecting data from 99 percent of England’s 8,020 general medical practices, researchers found that the locations with fluoridated water were 30 percent more likely to have high levels of hypothyroidism, compared to areas with low, natural levels of the chemical in the water.

Now, a report from the world’s oldest and most prestigious medical journal, The Lancet, has officially classified fluoride as a neurotoxin — in the same category as arsenic, lead and mercury.
The news was broken by author Stefan Smyle, who cited a report published in The Lancet Neurology, Volume 13, Issue 3, in the March 2014 edition, by authors Dr. Phillippe Grandjean and Philip J. Landrigan, MD. The report, which was officially released in 2014 and published in the journal, can be viewed by clicking here.

Neurodevelopmental disabilities, including autism, attention-deficit hyperactivity disorder, dyslexia, and other cognitive impairments, affect millions of children worldwide, and some diagnoses seem to be increasing in frequency. Industrial chemicals that injure the developing brain are among the known causes for this rise in prevalence. In 2006, we did a systematic review and identified five industrial chemicals as developmental neurotoxicants: lead, methylmercury, polychlorinated biphenyls, arsenic, and toluene. Since 2006, epidemiological studies have documented six additional developmental neurotoxicants—manganese, fluoride, chlorpyrifos, dichlorodiphenyltrichloroethane, tetrachloroethylene, and the polybrominated diphenyl ethers. We postulate that even more neurotoxicants remain undiscovered. To control the pandemic of developmental neurotoxicity, we propose a global prevention strategy. Untested chemicals should not be presumed to be safe to brain development, and chemicals in existing use and all new chemicals must therefore be tested for developmental neurotoxicity. To coordinate these efforts and to accelerate translation of science into prevention, we propose the urgent formation of a new international clearinghouse.