Source: https://www.infowars.com/posts/double-vaxxed-la-mayor-tests-positive-for-covid/
Despite being fully vaccinated, Los Angeles Mayor Eric Garcetti has tested positive while visiting the Cop26 climate change summit in Glasgow and will now be forced to self-isolate in his hotel room.
The Mayor’s official Twitter account made the announcement this afternoon.
VAXXED TV – VaxXed Stories: Eric and Ronnie in Denver, Colorado
Includes music and footage from Ronnie’s video for Eric, “Eric’s life before and after the Vaccine”. See it here:
Vaccines killed my 4 year old son
My own VaxXed versus unvaccinated
8 children- unvaccinated and healthy
Vaccine injuries
Vaxxed. Partially Vaxxed and unvaccinated
Hep B injured me
Unlocking key to autism
MMR vaccines gave my sons autism
Court ordered MMR on my son
A study published in the Journal of Toxicology and Environmental Health, Part A: Current Issues by the Department of Economics and Finance at the University of New York shows how researchers suspect one or more environmental triggers are needed to develop autism, regardless of whether individuals have a genetic predisposition or not. They determined that one of those triggers might be the “battery of vaccinations that young children receive.” Researchers found a positive and statistically significant relationship between autism and vaccinations. They determined that the higher the proportion of children receiving recommended vaccinations, the higher the prevalence of autism. A 1 % increase in vaccination was associated with an additional 680 children having autism. The results suggest that vaccines may be linked to autism and encourages more in depth study before continually administering these vaccines.
US National Library of Medicine
National Institutes of Health – 2011
Delong G.
Author information
Department of Economics and Finance, Baruch College/City University of New York, New York, New York, USA. gayle.delong@baruch.cuny.edu
Abstract
The reason for the rapid rise of autism in the United States that began in the 1990s is a mystery. Although individuals probably have a genetic predisposition to develop autism, researchers suspect that one or more environmental triggers are also needed. One of those triggers might be the battery of vaccinations that young children receive. Using regression analysis and controlling for family income and ethnicity, the relationship between the proportion of children who received the recommended vaccines by age 2 years and the prevalence of autism (AUT) or speech or language impairment (SLI) in each U.S. state from 2001 and 2007 was determined. A positive and statistically significant relationship was found: The higher the proportion of children receiving recommended vaccinations, the higher was the prevalence of AUT or SLI. A 1% increase in vaccination was associated with an additional 680 children having AUT or SLI. Neither parental behavior nor access to care affected the results, since vaccination proportions were not significantly related (statistically) to any other disability or to the number of pediatricians in a U.S. state. The results suggest that although mercury has been removed from many vaccines, other culprits may link vaccines to autism. Further study into the relationship between vaccines and autism is warranted.
A study published in the Journal of Toxicology by the Department of Neurosurgery at The Methodist Neurological Institute in Houston has shown that ASD is a disorder caused by a problem in brain development. They looked at B-cells and their sensitivity levels to thimerosal, a commonly used additive in many vaccines. They determined that ASD patients have a heightened sensitivity to thimerosal which would restrict cell proliferation that is typically found after vaccination. The research shows that individuals who have this hypersensitivity to thimerosal could make them highly susceptible to toxins like thimerosal, and that individuals with a mild mitochondrial defect may be affected by thimerosal. The fact that ASD patients’ B cells exhibit hypersensitivity to thimerosal tells us something.
Journal of Toxicology
Volume 2013 (2013), Article ID 801517, 11 pages
Martyn A. Sharpe, Taylor L. Gist, and David S. Baskin
Department of Neurosurgery, The Methodist Neurological Institute, 6560 Fannin Street, Scurlock Tower No. 944, Houston, TX 77030, USA
Abstract
The role of thimerosal containing vaccines in the development of autism spectrum disorder (ASD) has been an area of intense debate, as has the presence of mercury dental amalgams and fish ingestion by pregnant mothers. We studied the effects of thimerosal on cell proliferation and mitochondrial function from B-lymphocytes taken from individuals with autism, their nonautistic twins, and their nontwin siblings. Eleven families were examined and compared to matched controls. B-cells were grown with increasing levels of thimerosal, and various assays (LDH, XTT, DCFH, etc.) were performed to examine the effects on cellular proliferation and mitochondrial function. A subpopulation of eight individuals (4 ASD, 2 twins, and 2 siblings) from four of the families showed thimerosal hypersensitivity, whereas none of the control individuals displayed this response. The thimerosal concentration required to inhibit cell proliferation in these individuals was only 40% of controls. Cells hypersensitive to thimerosal also had higher levels of oxidative stress markers, protein carbonyls, and oxidant generation. This suggests certain individuals with a mild mitochondrial defect may be highly susceptible to mitochondrial specific toxins like the vaccine preservative thimerosal.
A study published in the Journal of Biomedical Sciences determined that the autoimmunity to the central nervous system may play a causal role in autism. Researchers discovered that because many autistic children harbour elevated levels of measles antibodies, they should conduct a serological study of measles-mumps-rubella (MMR) and myelin basic protein (MBP) autoantibodies. They used serum samples of 125 autistic children and 92 controlled children. Their analysis showed a significant increase in the level of MMR antibodies in autistic children. The study concludes that the autistic children had an inappropriate or abnormal antibody response to MMR. The study determined that autism could be a result from an atypical measles infection that produces neurological symptoms in some children. The source of this virus could be a variant of MV, or it could be the MMR vaccine.
Study – Abnormal measles-mumps-rubella antibodies and CNS autoimmunity in children with autism.
US National Library of Medicine
National Institutes of Health – 2002
Singh VK, Lin SX, Newell E, Nelson C.
Author information
Department of Biology and Biotechnology Center, Utah State University, Logan, Utah 84322, USA. singhvk@cc.usu.edu
Abstract
Autoimmunity to the central nervous system (CNS), especially to myelin basic protein (MBP), may play a causal role in autism, a neurodevelopmental disorder. Because many autistic children harbor elevated levels of measles antibodies, we conducted a serological study of measles-mumps-rubella (MMR) and MBP autoantibodies. Using serum samples of 125 autistic children and 92 control children, antibodies were assayed by ELISA or immunoblotting methods. ELISA analysis showed a significant increase in the level of MMR antibodies in autistic children. Immunoblotting analysis revealed the presence of an unusual MMR antibody in 75 of 125 (60%) autistic sera but not in control sera. This antibody specifically detected a protein of 73-75 kD of MMR. This protein band, as analyzed with monoclonal antibodies, was immunopositive for measles hemagglutinin (HA) protein but not for measles nucleoprotein and rubella or mumps viral proteins. Thus the MMR antibody in autistic sera detected measles HA protein, which is unique to the measles subunit of the vaccine. Furthermore, over 90% of MMR antibody-positive autistic sera were also positive for MBP autoantibodies, suggesting a strong association between MMR and CNS autoimmunity in autism. Stemming from this evidence, we suggest that an inappropriate antibody response to MMR, specifically the measles component thereof, might be related to pathogenesis of autism.
****************************************************
How to accept Jesus Christ as your personal Saviour
Testimony by Phil Robertson from Duck Dynasty
1 Corinthians 15 Authorized (King James) Version (AKJV)
1 Moreover, brethren, I declare unto you the gospel which I preached unto you, which also ye have received, and wherein ye stand;
2 by which also ye are saved, if ye keep in memory what I preached unto you, unless ye have believed in vain.
3 For I delivered unto you first of all that which I also received, how that Christ died for our sins according to the scriptures;
4 and that he was buried, and that he rose again the third day according to the scriptures:
Hebrews 6 Authorized (King James) Version (AKJV)
1 Therefore leaving the principles of the doctrine of Christ, let us go on unto perfection; not laying again the foundation of repentance from dead works, and of faith toward God,
2 of the doctrine of baptisms, and of laying on of hands, and of resurrection of the dead, and of eternal judgment.
3 And this will we do, if God permit.
4 For it is impossible for those who were once enlightened, and have tasted of the heavenly gift, and were made partakers of the Holy Ghost,
5 and have tasted the good word of God, and the powers of the world to come,
6 if they shall fall away, to renew them again unto repentance; seeing they crucify to themselves the Son of God afresh, and put him to an open shame.
7 For the earth which drinketh in the rain that cometh oft upon it, and bringeth forth herbs meet for them by whom it is dressed, receiveth blessing from God:
8 but that which beareth thorns and briers is rejected, and is nigh unto cursing; whose end is to be burned.
Paul Begley – Breaking: “Trump Calls For Turkey To Release Christian Pastor In Prison”
President Trump calls for Turkey to release Christian Pastor Andrew Brunson for jail http://www.paulbegleyprophecy.com also Help Us Spread the Word
Paul Begley – Prophecy Alert: “Trump Praying At Wall In Jerusalem 3,000 Year Prophecy
May 17, 2017
– FLASHBACK! ‘Concentration Camp Malls’ In ‘Retail Apocalypse’ America
By Stefan Stanford – All News Pipeline – Live Free Or Die
In this story published Tuesday over at ABC News they report that more people have been killed in Venezuela and hundreds injured as chaos erupted as another round of protests took place against Nicolas Maduro’s socialist government. With buildings being set on fire after what started out as a peaceful ‘sit-in against the dictatorship’ protests turned chaotic, nearly 2,000 people have been detained and the chaos in Venezuela shows no sign of stopping.
GenSix Productions – Giants, Little People & Subterranean Secrets with Steve Quayle & Klaus Dona
This is simply incredible. I guess we found the source of that ‘unknown’ radiation over Europe!
#atc #flying #chemtrails #radiation #europe
All Fish Caught And Tested Off The California Coast Were Positive For Fukushima Radiation…
*Strontium Mimics ➡Calcium.
*Cesium Mimics ➡Potassium.
*Plutonium Mimics ➡Iron.
*Iodine Mimics ➡Iodine.
https://miningawareness.wordpress.com/2015/02/26/plutonium-trojan-horse-in-the-body/
The 12 biggest SCIENCE LIES you’ve been told by corporations, government and the corrupt media….
Pedophilia Network Exposed in Australia — It Starts at the TOP, Just Like in the USA and UK
Australian woman Fiona Barrett showed a ton of courage in going public at a Sydney press conference in October 2015 and naming names.
Fiona, a former victim of Satanic ritual abuse and part of an international VIP pedophile ring, not only exposed the existence of the Satanic pedophilia network and its international child trafficking ring, but actually named 3 former Australian Prime Ministers and 1 former US President as perpetrators.
She reveals that this network, composed of famous actors, celebrities, judges, politicians and other high-flyers, has infiltrated all the key organizations and institutions in Australia – just as it has in the US and Britain.
WHAT’S GOING ON IN THE WORLD?
Fiona saw it all – Satanic ritual, rape, torture and murder – but actually says “the way I’ve been treated for reporting the crimes I’ve witnessed and experienced has been far worse than my original abuse experiences.”
That speaks volumes about people’s collective denial and amnesia, doesn’t it?
Breakthrough: GcMAF Treatment Kills Cancer Cells in Real Time. Holistic Doctors ‘Suicided’
By Ethan A. Huff via Real Farmacy
A breakthrough cancer treatment appears to be the reason why a handful of holistic doctors were recently found “suicided” is now gaining worldwide attention as a potential universal cure for cancer. And new microscopic footage released by First Immune shows this amazing remedy in action — the human protein GcMAF is visually seen activating the body’s own macrophages, which are then able to attack and destroy breast cancer cells in vitro.
The roughly two-minute video clip, which has been posted to YouTube, reveals the true healing power of GcMAF, a human protein that the body makes naturally but that some people lack or can’t produce in adequate volume.
By delivering an activated version of this substance intravenously, scientists have shown that the immune system can be fully invigorated to destroy cancer cells on its own without the need for chemotherapy or radiation.
New Guidelines for Safe Usage of Colloidal Silver
The Silver Safety Committee has announced its creation of the Silver Safety Pyramid, which is designed to enable anyone to easily determine safe usage levels of any dietary supplement containing silver, typically referred to as ionic silver or colloidal silver.
The Silver Safety Committee consists of doctors, chemistry professors and world leaders in health-freedom advocacy.
According to Herbert Slavin, M.D., director of the Institute of Advanced Medicine in Lauderhill, Florida, and a member of the Committee:
“This is an area where confusion and concern developed needlessly. Few things in life are as cut-and-dried as the fact that silver is completely safe when used within normal limits. The U.S. government provides a very clear guideline for the safe oral intake of silver. We’ve simply provided an easy method for applying that guideline to the safe use of any silver supplement product.”
The U.S. Environmental Protection Agency has a guideline called the Reference Dose (RfD) for safe limits on daily intake of silver. The EPA’s RfD guideline is specifically intended to keep a person’s intake of silver below the level that could possibly discolor the skin.
Says Jeffrey Blumer, M.D., Ph.D., director of the Center for Drug Research, the world’s largest clinical research center for pediatric drugs, and former director of the Greater Cleveland Poison Control Center:
“Common substances like table salt and aspirin are harmless with normal use, but excessive intake can become toxic and even life-threatening. With normal responsible usage, silver supplements are entirely harmless to humans.”
The Silver Safety Pyramid is based on the Committee’s Silver Safety Guideline, which recommends that a person’s intake of silver from dietary supplements be limited to 25 percent of the EPA’s recommended limit for total daily intake of silver.
It utilizes the Silver Safety Calculation, a simple mathematical formula that enables a person to easily determine how much to take of any silver-containing product to remain within the safety guidelines.
Study : Simultaneous sudden infant death syndrome.
J Forensic Leg Med. 2007 Feb;14(2):87-91.
Abstract
The simultaneous sudden deaths of twins rarely occur and therefore it has received limited attention in the medical literature. When the deaths of the twins meet the defined criteria for sudden infant death syndrome (SIDS) independently and take place within the same 24 h range it can be called as simultaneous SIDS (SSIDS). The case(s): Twin girls (3.5-month-old) were found dead by their mother in their crib, both in supine position. The infants were identical twins and delivered at a hospital by cesarean section. Both infants were healthy and did not have any serious medical history. Two days prior to the incident, the twins had received the second dose of oral polio, DPT and the first dose of hepatitis B vaccines and they had fever on the first day of the vaccination and been given teaspoonful of acetaminophen. Death scene investigation, judicial investigation, parental assessment, macroscopic and microscopic autopsy findings and the toxicological analysis did not yield any specific cause of death. The case(s) were referred to a supreme board composed of multidisciplinary medical professionals at the Institute of Forensic Medicine, Ministry of Justice, in Istanbul. The Board decided that the available data was consistent with SIDS. These SIDS case(s) are presented because twin SIDS are rare and this is the first time that a simultaneous twin SIDS have been reported in Turkey. Simultaneous SIDS cases have many implications regarding definition, diagnosis and medico-legal approach.
J Toxicol Environ Health A. 2011;74(14):903-16. doi: 10.1080/15287394.2011.573736.
Abstract
The reason for the rapid rise of autism in the United States that began in the 1990s is a mystery. Although individuals probably have a genetic predisposition to develop autism, researchers suspect that one or more environmental triggers are also needed. One of those triggers might be the battery of vaccinations that young children receive. Using regression analysis and controlling for family income and ethnicity, the relationship between the proportion of children who received the recommended vaccines by age 2 years and the prevalence of autism (AUT) or speech or language impairment (SLI) in each U.S. state from 2001 and 2007 was determined. A positive and statistically significant relationship was found: The higher the proportion of children receiving recommended vaccinations, the higher was the prevalence of AUT or SLI. A 1% increase in vaccination was associated with an additional 680 children having AUT or SLI. Neither parental behavior nor access to care affected the results, since vaccination proportions were not significantly related (statistically) to any other disability or to the number of pediatricians in a U.S. state. The results suggest that although mercury has been removed from many vaccines, other culprits may link vaccines to autism. Further study into the relationship between vaccines and autism is warranted.
Dr. Andrew Wakefield, a British doctor, may understand the issue of vaccine-induced autism better than anyone on the planet. Listen to the doctor-turned filmmaker (Vaxxed) tell the truth about how to end the autism epidemic.
Ever wonder WHY we NEED a religious exemption from vaccines?
Are you aware that some vaccines are made from ABORTIONS?
Marcella Piper-Terry explains in detail how abortions are used in vaccine manufacturing and the implications of that.
Interview by Polly Tommey and camera by Joshua Coleman and Anu Vaidya with editing by Joshua Coleman.
The Vaxxed bus makes a special stop in Fort Wayne, Indiana to talk to Independent Researcher Marcella Piper-Terry about religious exemptions from vaccines and aborted fetal cells. Interview by Polly Tommey and camera by Joshua Coleman and Anu Vaidya with editing by Joshua Coleman.
Autism-Vaccine Theory Yet to Be Debunked
Contrary to the popular misconception, the autism-vaccine link has never been disproven. The autism-vaccine debate has been going around for decades, yet until recently, no official safety study has been done by the CDC itself. Many other studies done had either conflict of interest or insufficient data (most importantly, the CDC admits that a study comparing vaccinated versus unvaccinated children has never been done).
In 2004 when the CDC finally concluded a long-term study on vaccinations and autism in children, the results were not what they expected. They found a potential link between the two, primarily in African American boys, and decided to hide the information from the public.
Their study was published, but the significant information was not, instead it was literally thrown into a huge garbage can.
This came to light in 2014 when a senior scientist at the CDC, Dr. William Thompson came forward, admitting to what they did. Florida U.S. Representative Bill Posey spoke about it to the House of Representatives urging for an official investigation, but not much has been done since.
Healthy Children Can Become Horribly Sick After Vaccinations
For many, these stories are nothing but anecdotes, but for thousands of families who have gone through this (and doctors who witnessed it), it is a real tragedy. More people are coming forward with eerily similar stories. Seemingly healthy children become sick after receiving vaccinations (some within hours), and many never recover.
Public health officials and the CDC say that vaccines are necessary for public health, pointing to their effect on disease outbreaks such as polio, measles and other preventable diseases. But critics say they’re unwilling to fairly study or even discuss the other side of the question: vaccine injured people.
One of the reasons we might not hear about them is that the only place the affected families can go to report injuries is to VAERS, Vaccine Adverse Event Reporting System, created by the CDC and FDA.
The site welcomes its visitors with: “Have you or your child had a reaction following vaccination?”
After that, families can ask for monetary compensation from what many call the vaccine court, an administrative procedure, which is run by a government program called 1986 National Childhood Vaccine Injury Act using government-funded science. The act was passed in large part because of lobbying from pharmaceutical companies, which now cannot be sued for anything related to the vaccines they make — a clear conflict of interest.
Most importantly, these hearings are not open to the public or press, so we rarely hear about them.
Porter Bridges developed brain damage after childhood vaccinations. Photo: Bought movie.
Some stories do find a way to get noticed. In 1994 the Bridges family filed a suit through the National Vaccine Injury Compensation Program, after their son Porter became autistic. In 2011 they won the case and received about $7 million. The court concluded that a combination of childhood vaccines caused Porter to have encephalopathy – brain damage.
(Porter’s story was thoroughly discussed in the movie Bought, a film bringing light to the money involved in the pharmaceutical industry and its effect in making vaccines).
Injuries such as encephalopathy are controversial because the defendants may say the child does not have autism, they have encephalopathy, and the link between autism and vaccines is therefore “disproved.”
But autism spectrum conditions have grown to include many symptoms, and the main one is brain developmental issues. Whether in the future, studies will be able to classify encephalopathy or brain damage and autism as the same thing, it’s worth noting that the two have many identical symptoms: confusion, memory issues, muscle weakness, twitching, trembling, difficulty speaking, seizures, and even coma.
And encephalopathy is a common vaccine injury. The VAERS site lists it as a possible result of the DTP shot (noticeable within 72 hours) and MMR (within 5-15 days).
One of the most famous MMR court cases is that of Bailey Banks. The court concluded that childhood vaccinations caused Acute Disseminated Encephalomyelitis or ADEM (intense brain swelling).
The true numbers of injured are hard to count, as many families never report them or ask for compensation knowing that it might take up to two decades to see the results.
Vaccine Pamphlets Themselves List Many Serious Side-Effects
Every vaccine comes with a long insert of side-effects, which are rarely shown to patients. And if one were to ask, doctors have been known to get upset.
Looking at an insert from any vaccine paints a similar picture. This is an insert for M-M-R II vaccine (measles, mumps, and rubella) made by Merck, one of the first biggest pharmaceutical companies.
First of all, the safety of this particular vaccine has been determined by studies on a small number of children, 284 total.
The vaccine has also never been studied for its effect on the development of the fetus in pregnant women.
The safety of this vaccine, when given before the age of 12 months, has not been established. It is also not 100% effective, like all vaccines.
Patients who may experience an adverse reaction are instructed to report it to VAERS.
The list of the adverse reactions reported is long, but what is particularly important are injuries to the nervous system:
Encephalitis; encephalopathy; measles inclusion body encephalitis (MIBE); subacute sclerosing panencephalitis (SSPE); Guillain-Barré Syndrome (GBS); acute disseminated encephalomyelitis (ADEM); transverse myelitis; febrile convulsions; afebrile convulsions or seizures; ataxia; polyneuritis; polyneuropathy; ocular palsies; paresthesia.
In the 2016 VAERS report (not yet complete), encephalopathy is mentioned many times, as well as autism (mentioned 97 times).
Patients’ families reported: “loss of speech, regression from previous milestones, a light went out from child’s eyes, fever, lethargy, refusing to eat, encephalopathy.”
“Difficulty breathing, fever, hive-like rashes. Currently being assessed for Autism spectrum, speech loss, occupational therapy, etc.”
“Insomnia, anxiety, paranoia, (GABA) seizures, tics…legs would suddenly give out and she would fall, acne, headaches, stomach aches, dizziness, regression, anemia, mood swings, emotional lability, cognitive decline, brain inflammation.”
If only half of America is properly vaccinated, where are the epidemics?
The argument for herd immunity was actually developed out of observations of natural immunity, not vaccination. Statisticians observed that populations were protected when sufficient members contracted the wild form of a disease, and subsequently acquired lifelong immunity. With vaccines, however, evidence shows that unvaccinated children may catch infectious diseases from vaccinated children. What is true of natural immunity is not true of vaccination.
The herd immunity argument has always been inconsistent. On the one hand, the theory goes, people who cannot receive vaccines for whatever reason are protected from the disease through a high level of vaccination in the rest of society. On the other hand, the theory continues, parents who don’t vaccinate their children put the health of wider society at risk. How can a handful of people not getting vaccinated be protected from getting sick, while at the same time being so disease-ridden that they make others sick? This doesn’t make sense.
While herd immunity may not exist, herd mentality most definitely does. Health authorities, media commentators, and schools and their parent–teacher associations waste no opportunity in perpetuating this myth. Proponents have done such a thorough job of convincing the public that a parent who questions it is treated like someone who thinks the earth is flat or believes climate change is a conspiracy. On the contrary: an unprejudiced view of the science about vaccines, and an examination of history, clearly show that the herd immunity theory is—and always has been—flawed.
Vaccines may have a place in our medical arsenal, but they are not the silver bullet they’re portrayed to be. Year after year the pharmaceutical industry, looking for lucrative new profit centers, churns out new vaccines. They use pseudo-science to convince the public that these products are safe and effective, and they use public shaming to convince the citizenry that non-compliance is a public health threat. This entire racket completely falls apart with a close examination of the herd immunity myth. Until we are honest in our assessment of both the safety and efficacy of vaccines, kids will continue to be hurt, rights will continue to be trampled, and mythology will continue to trump science.
Gretchen DuBeau is Executive Director of Alliance for Natural Health USA.
The Vaccine Did It: Mutated MMR Mumps Virus in the Brain of a Child Caused His Death, British Researchers Confirm
Posted on:
Sunday, January 22nd 2017 at 6:30 pm
Written By:
Celeste McGovern
The Vaccine Did It
A toddler who developed severe neurological symptoms including blindness associated with chronic encephalitis and died following MMR vaccination was found to have vaccine-derived mumps virus in his brain, a new study reports.
Published in the current issue of the journal, Acta Neuropathologica, the study is the first of its kind to conclusively demonstrate chronic brain damage in the form of “panencephalitis” due to a vaccine-derived strain of the mumps virus. In light of a recent epidemic of mumps in highly vaccinated populations, the research raises questions about the dangers of live vaccine virus mutations and about public health claims that the MMR is a completely safe and effective vaccine without serious side effects.
MMR, BRAIN INFECTION AND DEATH
The study describes an 18-month old infant who was diagnosed with Severe Combined Immunodeficiency Disease (SCID) — a serious immune system defect that may follow infection — four months after he received the triple Measles Mumps Rubella vaccine that contains live viruses.
The baby was treated for the illness but six months later became ill again with fever, rash, diarrhoea, lethargy and seizures. MRI scans of his brain showed evidence of encephalitis — brain inflammation due to infection.
The toddler was treated with antimicrobials, antivirals and steroids and sent home on anticonvulsant drugs. Over the next few months, behavioural problems became obvious, his hearing was impaired and his speech and language were delayed. A year later, by then four years old, he was still suffering from seizures and he became increasingly lethargic, disoriented and agitated. His walking was increasingly uncoordinated and he began to lose his eyesight.
A repeat MRI scan of the boy’s brain revealed abnormalities and a brain biopsy was taken at Great Ormond Street Hospital for Children in London. It revealed neuronal death and evidence of central nervous system damage and chronic inflammation. Despite aggressive treatment, his seizures increased, he became weak on his left side, went blind and the five-year-old died seven weeks later.
VACCINE VIRUS CONFIRMED
Spinal fluid and urine samples collected during the boy’s last hospitalisation, as well as RNA re-extracted from his brain biopsy, were sent to the Public Health England Virus Reference Laboratory for sequencing.
Researchers, led by Sofia Morfopoulou of the Division of Infection and Immunity, University College London, and at the National Institute for Biological Standards and Control, used deep sequencing technology to identify the MuV -JL5 vaccine virus strain in the boy’s brain biopsy which was negative for all other viruses.
Genetic Drift and Outbreaks
Mutations in the mumps vaccine virus from that in the batch of the vaccine the boy had received were also detected. The study refers to a 2015 study confirming “genetic instability” of mumps vaccine virus that leads to “genetic drift” between different vaccine batches and may explain why some mumps vaccines induce more serious adverse reactions than others, especially when they are grown on different media.
This science may also explain why the mumps vaccine is failing. A recent outbreak among more than 1,600 mostly vaccinated people in Arkansas has public health officers there admitting that the vaccine isn’t protecting against emerging new strains of the virus.
It’s part of a growing phenomenon that scientists are reporting in many vaccines called “sero-conversion” – when vaccines diminish the strain of a virus they are targeting, but another strain of the same virus blooms — just as antibiotics wipe out bacterial infections but leave antibiotic-resistant superbugs to thrive.
Study : The administration of intranasal live attenuated influenza vaccine induces changes in the nasal microbiota and nasal epithelium gene expression profiles
Background
Viral infections such as influenza have been shown to predispose hosts to increased colonization of the respiratory tract by pathogenic bacteria and secondary bacterial pneumonia. To examine how viral infections and host antiviral immune responses alter the upper respiratory microbiota, we analyzed nasal bacterial composition by 16S ribosomal RNA (rRNA) gene sequencing in healthy adults at baseline and at 1 to 2 weeks and 4 to 6 weeks following instillation of live attenuated influenza vaccine or intranasal sterile saline. A subset of these samples was submitted for microarray host gene expression profiling.
Results
We found that live attenuated influenza vaccination led to significant changes in microbial community structure, diversity, and core taxonomic membership as well as increases in the relative abundances of Staphylococcus and Bacteroides genera (both p < 0.05). Hypergeometric testing for the enrichment of gene ontology terms in the vaccinated group reflected a robust up-regulation of type I and type II interferon-stimulated genes in the vaccinated group relative to controls. Translational murine studies showed that poly I:C administration did in fact permit greater nasal Staphylococcus aureus persistence, a response absent in interferon alpha/beta receptor deficient mice.
Conclusions
Collectively, our findings demonstrate that although the human nasal bacterial community is heterogeneous and typically individually robust, activation of a type I interferon (IFN)-mediated antiviral response may foster the disproportionate emergence of potentially pathogenic species such as S. aureus.
Sarah M. Connaughton, Jun X. Wheeler, Eva Vitková, Philip Minor and Silke Schepelmann
Vaccine, 2015-08-26, Volume 33, Issue 36, Pages 4586-4593, Copyright © 2015 The Authors
Highlights
• Mumps vaccines contain live attenuated viruses that are manufactured in cell substrates.
• The production of the JL-CK vaccine in primary canine kidney cells is atypical.
• Genetic changes introduced by different cell types have not been investigated.
• JL-CK vaccine contains a unique mix of mumps viruses that have acquired a number of mutations.
• Growth in cell or animal substrates dramatically alters the population dynamic of JL-CK.
Abstract
Mumps vaccines are live attenuated viruses. They are known to vary in effectiveness, degree of attenuation and adverse event profile. However, the underlying reasons are poorly understood. We studied two closely related mumps vaccines which originate from the same attenuated Jeryl Lynn-5 strain but have different efficacies. Jeryl Lynn-Canine Kidney (JL-CK), produced on primary canine kidney cells, is less effective than RIT4385, which is produced on chicken embryo fibroblasts. JL-CK and RIT4385 could be distinguished by a number of in vitro and in vivo properties. JL-CK produced heterogeneous, generally smaller plaques than RIT4385, but gave 100-fold higher titres when grown in cells and showed a higher degree of hydrocephalus formation in neonatal rat brains. Sanger sequencing of JL-CK identified 14 regions of heterogeneity throughout the genome. Plaque purification of JL-CK demonstrated the presence of five different Jeryl Lynn-5 variants encompassing the 14 mutations. One JL-CK mutation was associated with a small plaque phenotype, the effects of the others in vitro or in vivo were less clear. Only 4% of the JL-CK population corresponded to the parental Jeryl Lynn-5 strain. Next generation sequencing of JL-CK and virus before and after growth in cell lines or neonatal rat brains showed that propagation in vitro or in vivo altered the population dramatically. Our findings indicate that growth of JL-CK in primary canine kidney cells resulted in the selection of a mixture of mumps virus variants that have different biological properties compared to the parent Jeryl Lynn-5 virus. We also report three previously unknown heterogenic regions within the N gene of the RIT4385 vaccine.
According to a recent article from EcoWatch.com by Zen Honeycutt, MAA’s founder, five childhood vaccines were sent by the group to an independent lab earlier this year, and all five tested positive for glyphosate — with the controversial MMR (triple dose) vaccine showing levels 25 times higher than other vaccines.
the news network 