Vaccine News – Study – The Blood-Brain Barrier Bottleneck in Brain Drug Development

Study – Systematic review and meta-analysis links autism and toxic metals and highlights the impact of country development status: Higher blood and erythrocyte levels for mercury and lead, and higher hair antimony, cadmium, lead, and mercury.

US National Library of Medicine
National Institutes of Health – 3 Oct 2017

Saghazadeh A – 1, Rezaei N – 2.
Author information
1 Research Center for Immunodeficiencies, Children’s Medical Center, Tehran University of Medical Sciences, Tehran, Iran; MetaCognition Interest Group (MCIG), Universal Scientific Education and Research Network (USERN), Tehran, Iran.
2 Research Center for Immunodeficiencies, Children’s Medical Center, Tehran University of Medical Sciences, Tehran, Iran; Department of Immunology, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran; Systematic Review and Meta-analysis Expert Group (SRMEG), Universal Scientific Education and Research Network (USERN), Boston, MA, USA. Electronic address: Rezaei_nima@tums.ac.ir.

Abstract
BACKGROUND:
Autism spectrum disorder (ASD) is a heterogeneous neurodevelopmental disorder that affects cognitive and higher cognitive functions. Increasing prevalence of ASD and high rates of related comorbidities has caused serious health loss and placed an onerous burden on the supporting families, caregivers, and health care services. Heavy metals are among environmental factors that may contribute to ASD. However, due to inconsistencies across studies, it is still hard to explain the association between ASD and toxic metals. Therefore the objective of this study was to investigate the difference in heavy metal measures between patients with ASD and control subjects.
METHODS:
We included observational studies that measured levels of toxic metals (antimony, arsenic, cadmium, lead, manganese, mercury, nickel, silver, and thallium) in different specimens (whole blood, plasma, serum, red cells, hair and urine) for patients with ASD and for controls. The main electronic medical database (PubMed and Scopus) were searched from inception through October 2016.
RESULTS:
52 studies were eligible to be included in the present systematic review, of which 48 studies were included in the meta-analyses. The hair concentrations of antimony (standardized mean difference (SMD)=0.24; 95% confidence interval (CI): 0.03 to 0.45) and lead (SMD=0.60; 95% confidence interval (CI): 0.17 to 1.03) in ASD patients were significantly higher than those of control subjects. ASD patients had higher erythrocyte levels of lead (SMD=1.55, CI: 0.2 to 2.89) and mercury (SMD=1.56, CI: 0.42 to 2.70). There were significantly higher blood lead levels in ASD patients (SMD=0.43, CI: 0.02 to 0.85). Sensitivity analyses showed that ASD patients in developed but not in developing countries have lower hair concentrations of cadmium (SMD=-0.29, CI: -0.46 to -0.12). Also, such analyses indicated that ASD patients in developing but not in developed lands have higher hair concentrations of lead (SMD=1.58, CI: 0.80 to 2.36) and mercury (SMD=0.77, CI: 0.31 to 1.23). These findings were confirmed by meta-regression analyses indicating that development status of countries significantly influences the overall effect size of mean difference for hair arsenic, cadmium, lead, and mercury between patients with ASD and controls.
CONCLUSION:
The findings help highlighting the role of toxic metals as environmental factors in the etiology of ASD, especially in developing lands. While there are environmental factors other than toxic metals that greatly contribute to the etiology of ASD in developed lands. It would be, thus, expected that classification of ASD includes etiological entities of ASD on the basis of implication of industrial pollutants (developed vs. developing ASD).

Study – Autism: A form of lead and mercury toxicity

Environmental Toxicology and Pharmacology
Volume 38, Issue 3, November 2014, Pages 1016–1024

Highlights
•Autism is a developmental disability characterized by severe, pervasive deficits in social interaction and communications.
•Lead and mercury two of the most common heavy metals in the environment.
•Lead and mercury can lead to autistic disorders.
•Many risk factors contribute to the high level of heavy metals in autistic children.
•Defect in the metabolism of the heavy metals in autistic children also contribute to the high level of these heavy metals in their body.
•Chelating agents can be used in the treatment of the autistic disorders.

Abstract
Aim
Autism is a developmental disability characterized by severe deficits in social interaction and communication. The definite cause of autism is still unknown. The aim of this study is to find out the relation between exposure to Lead and/or mercury as heavy metals and autistic symptoms, dealing with the heavy metals with chelating agents can improve the autististic symptoms.

Method
Blood and hair samples were obtained from 45 children from Upper Egypt with autism between the ages of 2 and 10 years and 45 children served as controls in the same age range, after taken an informed consent and fill a questionnaire to assess the risk factors. The samples were analyzed blindly for lead and mercury by using atomic absorption and ICP-MS. Data from the two groups were compared, then follow up of the autistic children after treatment with chelating agents were done.

Results
The results obtained showed significant difference among the two groups, there was high level of mercury and lead among those kids with autism. Significant decline in the blood level of lead and mercury with the use of DMSA as a chelating agent. In addition, there was decline in the autistic symptoms with the decrease in the lead and mercury level in blood.

Conclusion
Lead and mercury considered as one of the main causes of autism. Environmental exposure as well as defect in heavy metal metabolism is responsible for the high level of heavy metals. Detoxification by chelating agents had great role in improvement of those kids.

Study – The Blood-Brain Barrier: Bottleneck in Brain Drug Development

US National Library of Medicine
National Institutes of Health – Jan 2005

William M. Pardridge
Department of Medicine, UCLA, Los Angeles, California 90024
Address correspondence and reprint requests to William M. Pardridge, M.D., UCLA Warren Hall, 13-164, 900 Veteran Avenue, Los Angeles,

ABSTRACT
Summary: The blood-brain barrier (BBB) is formed by the brain capillary endothelium and excludes from the brain ∼100% of large-molecule neurotherapeutics and more than 98% of all small-molecule drugs. Despite the importance of the BBB to the neurotherapeutics mission, the BBB receives insufficient attention in either academic neuroscience or industry programs. The combination of so little effort in developing solutions to the BBB problem, and the minimal BBB transport of the majority of all potential CNS drugs, leads predictably to the present situation in neurotherapeutics, which is that there are few effective treatments for the majority of CNS disorders. This situation can be reversed by an accelerated effort to develop a knowledge base in the fundamental transport properties of the BBB, and the molecular and cellular biology of the brain capillary endothelium. This provides the platform for CNS drug delivery programs, which should be developed in parallel with traditional CNS drug discovery efforts in the molecular neurosciences.

VAXXED TV – Nick Johansen #vaxxed #PrayBig

Dr. Judy Mikovits, PhD Research Scientist at #TxMFA #TxMFA2017
Dr. Judy Mikovits, PhD research scientist, dives deep into the crude science of vaccination

Austin Bennett #vaxxed #PrayBig

Dawn Richardson

David Oldham

Barbara Loe Fisher #vaxxed #truth #science #praybig

Q&A vaccine syndrome

Global Vaccine Initiative Houston Protest #TxMFA #TxMFA2017
Jonathan Tommey and The Vaxxed Team hit the ground running at the Texas Medical Freedom Alliance world symposium in Housant, Texas.
They discusses vaccine safety concerns with our #TexasPeeps protesting on the ground and also interview medical doctor, Jim Meehan, M.D. with regard to his passion for exposing the deception endemic to the present vaccine paradigm.

Glaxo’s Vaccine Trials survivor speaks out
David tells his story and presents documentation of his history going through the Glaxo’s trials. His mother was told he had passed as an infant here they kept him as an orphan until 4 years old.
Interview recorded on May 5th, 2017 in The United Kingdom

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How to accept Jesus Christ as your personal Saviour

Testimony by Phil Robertson from Duck Dynasty

1 Corinthians 15 Authorized (King James) Version (AKJV)
1 Moreover, brethren, I declare unto you the gospel which I preached unto you, which also ye have received, and wherein ye stand;
2 by which also ye are saved, if ye keep in memory what I preached unto you, unless ye have believed in vain.
3 For I delivered unto you first of all that which I also received, how that Christ died for our sins according to the scriptures;
4 and that he was buried, and that he rose again the third day according to the scriptures:

Hebrews 6 Authorized (King James) Version (AKJV)
1 Therefore leaving the principles of the doctrine of Christ, let us go on unto perfection; not laying again the foundation of repentance from dead works, and of faith toward God,
2 of the doctrine of baptisms, and of laying on of hands, and of resurrection of the dead, and of eternal judgment.
3 And this will we do, if God permit.
4 For it is impossible for those who were once enlightened, and have tasted of the heavenly gift, and were made partakers of the Holy Ghost,
5 and have tasted the good word of God, and the powers of the world to come,
6 if they shall fall away, to renew them again unto repentance; seeing they crucify to themselves the Son of God afresh, and put him to an open shame.
7 For the earth which drinketh in the rain that cometh oft upon it, and bringeth forth herbs meet for them by whom it is dressed, receiveth blessing from God:
8 but that which beareth thorns and briers is rejected, and is nigh unto cursing; whose end is to be burned.

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Vaccine News – A mother shares her story about her children’s reactions to the vaccines – VAXXED TV

VAXXED TV – Barbara Loe Fisher #vaxxed #truth #science #praybig

Q&A vaccine syndrome

Global Vaccine Initiative Houston Protest #TxMFA #TxMFA2017
Jonathan Tommey and The Vaxxed Team hit the ground running at the Texas Medical Freedom Alliance world symposium in Housant, Texas.
They discusses vaccine safety concerns with our #TexasPeeps protesting on the ground and also interview medical doctor, Jim Meehan, M.D. with regard to his passion for exposing the deception endemic to the present vaccine paradigm.

Banned From Australia! #VaxxedAustralia #VaxxedWorld

Glaxo’s Vaccine Trials survivor speaks out
David tells his story and presents documentation of his history going through the Glaxo’s trials. His mother was told he had passed as an infant here they kept him as an orphan until 4 years old.
Interview recorded on May 5th, 2017 in The United Kingdom

I can’t believe they are doing this!
Patricia Gua tells of her injuries from receiving the HEP-B vaccination.

What If I Harmed My Children
Kelly Johnson, author of “What If?: I Harmed My Children” gives detailed accounts of her experiences with her kids which inspired her to write the book

I had every reaction documented – Liola shares about the details of her children’s reactions to vaccinations and the challenges they faced.
Interview recorded on May 5th, 2017 in The United Kingdom

It’s sad we have to learn the hard way
A mother shares her story about her children’s reactions to the vaccines.

Know Your Body

 

How to accept Jesus Christ as your personal Saviour

1 Corinthians 15 Authorized (King James) Version (AKJV)
1 Moreover, brethren, I declare unto you the gospel which I preached unto you, which also ye have received, and wherein ye stand;
2 by which also ye are saved, if ye keep in memory what I preached unto you, unless ye have believed in vain.
3 For I delivered unto you first of all that which I also received, how that Christ died for our sins according to the scriptures;
4 and that he was buried, and that he rose again the third day according to the scriptures:

Hebrews 6 Authorized (King James) Version (AKJV)
1 Therefore leaving the principles of the doctrine of Christ, let us go on unto perfection; not laying again the foundation of repentance from dead works, and of faith toward God,
2 of the doctrine of baptisms, and of laying on of hands, and of resurrection of the dead, and of eternal judgment.
3 And this will we do, if God permit.
4 For it is impossible for those who were once enlightened, and have tasted of the heavenly gift, and were made partakers of the Holy Ghost,
5 and have tasted the good word of God, and the powers of the world to come,
6 if they shall fall away, to renew them again unto repentance; seeing they crucify to themselves the Son of God afresh, and put him to an open shame.
7 For the earth which drinketh in the rain that cometh oft upon it, and bringeth forth herbs meet for them by whom it is dressed, receiveth blessing from God:
8 but that which beareth thorns and briers is rejected, and is nigh unto cursing; whose end is to be burned.

 

Vaccine News – Are #vaccines worth this risk?

Il documentario sui vaccini che ti toglie ogni dubbio
The documentary about vaccines that takes away all doubt

Dave Brenda McDowell visit the VaxXed bus while in Detroit, Michigan to the story of all three of their triplets vaccine injury stories following the pneumococcal vaccine. Interview by Polly Tommey with camera and editing by Joshua Coleman. #VaxXed #VaxWithUs #pneumococcal

Dangerous Vaccine Gardasil Begins Trial On Babies

 

Virologist Nobel Prize for contributing to the discovery of aids has just two things to say about vaccines, and the damage they are causing in the us and not just. Share in mass.
Otherwise, keep listening to’s stories and the company.

12 dirty vaccines. Learn more to be aware and prepared.
#LibertàDiScelta, #LIBERASCELTA, #NOISIAMO, #ILSENTIERODINICOLA, #diretta, #fiaccolata, #libertà, #scelta, #vaccini, #vaccinipuliti, #lorenzin, #bugiardina

The first-of-its-kind study of the health of vaccinated vs unvaccinated American homeschooled children indicates vaccines have effects beyond stimulating an immune response that parents, scientists and doctors should be aware of and concerned about. Read more here http://hubs.ly/H07n_MF0

Fluoride warnings are now being issued to infants. Thoughts…?

Ferdinando Imposimato: “il governo è illegittimo…la legge e la costituzione sono dalla nostra parte…e anche se passa il decreto non obbedite…”
Ferdinando Imposimato: ” the government is illegitimate… the law and the constitution are on our side… and even if the decree passes, do not obey…”

What’s the deal with Whooping Cough? Why are there so many outbreaks? Does the vaccine even work? Why do so many vaccinated people get Whooping Cough? Is it dangerous for babies? Part 1 of 3.
Shares work better than likes!
Medical bracelets, T-Shirts, Books & Stickers for sale: http://myincredibleopinion.com
All video episodes on YouTube: https://www.youtube.com/c/MyIncredibleOpinionWithForrestMaready

The taxpayers of America foot the bill for all vaccine-injury compensation, while the vaccine makers continue to rake in billions each year… and precious children pay the ultimate price with lifelong disability and sometimes their very lives. Protect yourself and your CHILDREN from this corrupt, heartless system >>> tinyurl.com/9Episodes
Why is there still a vaccine/autism controversy?
Because vaccine makers cannot be sued when their vaccines kill or cripple kids. The vaccine makers lobbied congress to pass laws protecting them from all liability. Families have been blocked from getting into a REAL court to prove that vaccines have caused their child’s autism.
Utah now has the highest rate of autism in the world with 1 in 10 boys and 1 in 33 girls being inflicted with this preventable neurobehavioral disorder. Even very conservative numbers place the National average at an appalling 1 in 50. When you compare the increase in the number of vaccinated children with the number of autistic and neuro-injured over the last 60 years, they are the same.
The number of children killed and permanently maimed by vaccines far exceeds the number of Jews killed by the death camps of Nazi Germany. And just as the people of Germany turned a blind eye to that atrocity, so do many of your neighbors, politicians and doctors. They are modern deniers and won’t risk their own comfort and standing to save any of the children being slaughtered and crippled for profit.
The Canary Party presents a video on the corrupt Vaccine Injury Compensation Program to show how the federal government and pharmaceutical companies continue to get away with claiming that vaccines don’t cause autism in the face of mounting evidence that they are doing just that in a growing number of children.
Protect yourself and your CHILDREN from this corrupt, heartless system >>> tinyurl.com/9Episodes
#RevolutionForChoice #HearThisWell #VAXXED #InformedConsent #VaccineCourt

Q&A Miami Australia #vaxxed #Truth #science #Praybig #Australia

This is an incredible breakthrough story of Crystal Brown who was diagnosed with Guillain-Barre Syndrome, a rare condition in which the immune system attacks part of the nervous system.
Read the comments and be shocked at how common this is. And how many were caused by a vaccine.
And isn’t it curious to note the similarities between GBS and polio? Makes you wonder how many “polio” cases were vaccine reactions back before the vaccine was introduced and the diagnostic measures were drastically changed.
Her story and fight is inspirational ❤❤❤
Support Crystal and her family by donating here: http://bit.ly/cbgofundme

#VaXism NEWS
But what about #polio?

http://www.whale.to/c/DissolvingIllusions-Polio.pdf
http://www.dissolvingillusions.com/

#VaXism NEWS

Lorenzin tieni alla Salute dei Cittadini?

Lorenzin, do you keep people’s health?

Piazza Montecitorio July 24, 2017
Freedom Rally…..
With the intervention of judge ferdinando imposimato from the minute 17
Ferdinando Imposimato: ” the government is illegitimate… the law and the constitution are on our side… and even if the decree passes, do not obey…”

Statistici EXTREM DE IMPORTANTE despre reactiile post-vaccinale
iulie 14, 2017

Damon Beard Update – Feel free to share.
#VaXism NEWS
Are #vaccines worth this risk?

Vaccine resource file

If you have a daughter approaching the age of 12-14, she will soon be adamantly encouraged, by the attending nurse at her school, and by your very own family doctor, when you are out of the office, to receive the Gardasil HPV (human papillomavirus) vaccine, behind your back.
Based on the pattern we are seeing nurses are instructed to suggest… “You don’t want to get cervical cancer, do you?”
Inexplicably, this dangerous vaccine contains L-histidine, an essential amino acid, which plays a vital role in pregnancy; the synthetic form of which can also pass through the placental wall to the fetus. This could be the direct cause to the spontaneous miscarriage and birth defects in some of the babies.
Whenever a vital, naturally occurring substance such as L-histidine is injected into the body subcutaneously or intramuscularly (alongside heavy metals, live/attenuated viruses, detergents & antibiotic excipients etc), a counter effect inevitably occurs where-in the immune system cannot differentiate between the naturally occurring amino acid in the body from that present in the vaccine; registering all these intruders as a common enemy of toxic debris. The immune system instinctively kicks into overdrive, alerting any available antibodies throughout the body to identify & eliminate deposits of L-histidine it encounters in its path.
The end result, in each case, we’re seeing the antithesis of nature’s course develop, as the body, stripped of one or more primary components, is now, in essence, at war with itself. What follows is a cascade of unfortunate auto-immune reactions; neurological & neuro-developmental breakdown.
“I am here today because my daughter was harmed by the Gardasil vaccine. My daughter was actually sterilized by the vaccine. I am begging you, do not expand this vaccine until there are answers to the problems that have already arisen. How many children will have to die because this vaccine was a mistake of crazy proportion? How many will be sterilized?” Gardasil victim’s mother
‘HPV Gardasil Vaccine Killed Our Daughter: This is our daughter Jessica Ericzon, one day we came home from work and found her dead on the bathroom floor. An honor student, an all star athlete, never a medical condition in her life. When the coroner called and said her heart just stopped, she was dead before she hit the floor and he couldn’t tell why, we just couldn’t believe it.‘
The 3 doses required to complete the HPV vaccination regime are so intense, nurses administering the injections are advised to ask patients to lay down during the procedure. In many instances girls have fainted on the spot or gone into sudden seizures.
Think twice. The Gardasil Vaccine is completely unnecessary, and extraordinarily hazardous to her health.
Vaccine Resistance Movement
http://vaccineresistancemovement.org/?p=7579