Top doctors reveal that vaccines can trigger autoimmunity, turning our immune systems against us
(NaturalNews) Dr. Yehuda Shoenfeld is an Israeli clincian who has been extensively studying the human immune system for more than thirty years. Some say he is at the pinnacle of his profession, and that he is at the core of its foundation. He’s written 25 textbooks on the subject — some of which are key to the backbone of clincial practice. Dr. Shoenfeld has even been referred to as the “Godfather of Autoimmunology.” Autoimmunology is the study of the immune system when it is has turned against itself, resulting in a myriad of conditions including ulcertive colitis, multiple sclerosis and type 1 diabetes.
Lately, Dr. Shoenfeld has been shaking up the world of immunology with evidence that suggests that vaccines may indeed be playing a role in the onset of autoimmune disease. Specifically, some of the star ingredients found in vaccines — like aluminum, a toxic metal — are likely at the helm of the worldwide increase in autoimmune disorders. Evidence supporting this theory has been mounting over the last 15 years, but a noticeably stark increase in research has occured in the last five years. For example, recent study, authored by Dr. Shoenfeld and his colleagues, was published by the journal Pharmacological Research in 2015. In their report, the researchers identified four groups of people who will be most at risk of developing an autoimmune disease following vaccination.
The paper’s authors note that while vaccines may help to prevent illnesses that can cause autoimmunity, “On the other hand, many reports that describe post-vaccination autoimmunity strongly suggest that vaccines can indeed trigger autoimmunity.” The researchers state that “Almost all types of vaccines have been reported to be associated with the onset of ASIA [autoimmune/inflammatory syndrome induced by adjuvants].” The autoimmune diseases that may develop after vaccination include arthritis, lupus (systemic lupus erythematosus, SLE) diabetes mellitus, thrombocytopenia, vasculitis, dermatomyosiositis, Guillain-Barre syndrome and demyelinating disorders. Demyelinating disorders include conditions like multiple sclerosis. Demyelination refers to degradation of the myelin sheath — an insulating material that covers nerves — and results in impaired function of said nerves.
The term ASIA first appeared in the Journal of Autoimmunology a few years ago and is used as an umbrella term to describe a group of similar symptoms that appear after exposure to an adjuvant. Adjuvants are environmental agents, including common vaccine ingredients, that are known to spark the immune system into action. Using ASIA as a model, a massive amount of research has been conducted to begin answering questions surrounding environmental toxins, particularly the metal aluminum used in vaccines, and how they can create an immune system chain reaction in vulnerable individuals, as well as how they can possibly lead to autoimmune disease.
Autoimmune disease is the result of the body’s immune system turning against itself and the human body. When the immune system is functioning normally, it attacks foreign invaders of the body, such as a pathogenic bacteria. In the case of autoimmune disease, however, the immune system has begun attacking the body’s own cells somewhere within the body. In the case of type 1 diabetes, the immune system has targeted the Islets of Langerhans found in the pancreas. In rheumatoid arthritis, the immune system has begun attacking joint tissue. Similar events happen within other autoimmune diseases, but affecting different types of bodily tissues.
Several studies have indicated that the aluminium currently being used in vaccines is a great cause for concern, especially when it comes to autoimmune disease. A 2012 paper authored by researchers from the Neural Dynamics Research Group of the Department of Ophthalmology and Visual Sciences at the University of British Columbia, located in Canada, noted, “According to the US Food and Drug Administration, safety assessments for vaccines have often not included appropriate toxicity studies because vaccines have not been viewed as inherently toxic.”
Attacking Ourselves: Top Doctors Reveal Vaccines Turn Our Immune System Against Us
Tuesday, February 24th 2015 at 6:45 pm
This article is copyrighted by GreenMedInfo LLC, 2015
The research is hard to ignore, vaccines can trigger autoimmunity with a laundry list of diseases to follow. With harmful and toxic metals as some vaccine ingredients, who is susceptible and which individuals are more at risk?
No one would accuse Yehuda Shoenfeld of being a quack. The Israeli clinician has spent more than three decades studying the human immune system and is at the pinnacle of his profession. You might say he is more foundation than fringe in his specialty; he wrote the textbooks. The Mosaic of Autoimmunity, Autoantibodies, Diagnostic Criteria in Autoimmune Diseases, Infection and Autoimmunity, Cancer and Autoimmunity – the list is 25 titles long and some of them are cornerstones of clinical practice. Hardly surprising that Shoenfeld has been called the “Godfather of Autoimmunology” – the study of the immune system turned on itself in a wide array of diseases from type 1 diabetes to ulcerative colitis and multiple sclerosis.
But something strange is happening in the world of immunology lately and a small evidence of it is that the Godfather of Autoimmunology is pointing to vaccines – specifically, some of their ingredients including the toxic metal aluminum – as a significant contributor to the growing global epidemic of autoimmune diseases. The bigger evidence is a huge body of research that’s poured in in the past 15 years, and particularly in the past five years. Take for example, a recent article published in the journal Pharmacological Research in which Shoenfeld and colleagues issue unprecedented guidelines naming four categories of people who are most at risk for vaccine-induced autoimmunity.
“On one hand,” vaccines prevent infections which can trigger autoimmunity, say the paper’s authors, Alessandra Soriano, of the Department of Clinical Medicine and Rheumatology at the Campus Bio-Medico University in Rome, Gideon Nesher, of the Hebrew University Medical School in Jerusalem and Shoenfeld, founder and head of the Zabludowicz Center of Autoimmune Diseases in the Sheba Medical Center at Tel Hashomer. He is also editor of three medical journals and author of more than 1,500 research papers across the spectrum of medical journalism and founder of the International Congress on Autoimmunology. “On the other hand, many reports that describe post-vaccination autoimmunity strongly suggest that vaccines can indeed trigger autoimmunity. Defined autoimmune diseases that may occur following vaccinations include arthritis, lupus (systemic lupus erythematosus, SLE) diabetes mellitus, thrombocytopenia, vasculitis, dermatomyosiositis, Guillain-Barre syndrome and demyelinating disorders. Almost all types of vaccines have been reported to be associated with the onset of ASIA.”
Study – Mechanisms of aluminum adjuvant toxicity and autoimmunity in pediatric populations.
Immune challenges during early development, including those vaccine-induced, can lead to permanent detrimental alterations of the brain and immune function. Experimental evidence also shows that simultaneous administration of as little as two to three immune adjuvants can overcome genetic resistance to autoimmunity. In some developed countries, by the time children are 4 to 6 years old, they will have received a total of 126 antigenic compounds along with high amounts of aluminum (Al) adjuvants through routine vaccinations. According to the US Food and Drug Administration, safety assessments for vaccines have often not included appropriate toxicity studies because vaccines have not been viewed as inherently toxic. Taken together, these observations raise plausible concerns about the overall safety of current childhood vaccination programs. When assessing adjuvant toxicity in children, several key points ought to be considered: (i) infants and children should not be viewed as “small adults” with regard to toxicological risk as their unique physiology makes them much more vulnerable to toxic insults; (ii) in adult humans Al vaccine adjuvants have been linked to a variety of serious autoimmune and inflammatory conditions (i.e., “ASIA”), yet children are regularly exposed to much higher amounts of Al from vaccines than adults; (iii) it is often assumed that peripheral immune responses do not affect brain function. However, it is now clearly established that there is a bidirectional neuro-immune cross-talk that plays crucial roles in immunoregulation as well as brain function. In turn, perturbations of the neuro-immune axis have been demonstrated in many autoimmune diseases encompassed in “ASIA” and are thought to be driven by a hyperactive immune response; and (iv) the same components of the neuro-immune axis that play key roles in brain development and immune function are heavily targeted by Al adjuvants. In summary, research evidence shows that increasing concerns about current vaccination practices may indeed be warranted. Because children may be most at risk of vaccine-induced complications, a rigorous evaluation of the vaccine-related adverse health impacts in the pediatric population is urgently needed.
Study – Predicting post-vaccination autoimmunity: who might be at risk?
Vaccinations have been used as an essential tool in the fight against infectious diseases, and succeeded in improving public health. However, adverse effects, including autoimmune conditions may occur following vaccinations (autoimmune/inflammatory syndrome induced by adjuvants–ASIA syndrome). It has been postulated that autoimmunity could be triggered or enhanced by the vaccine immunogen contents, as well as by adjuvants, which are used to increase the immune reaction to the immunogen. Fortunately, vaccination-related ASIA is uncommon. Yet, by defining individuals at risk we may further limit the number of individuals developing post-vaccination ASIA. In this perspective we defined four groups of individuals who might be susceptible to develop vaccination-induced ASIA: patients with prior post-vaccination autoimmune phenomena, patients with a medical history of autoimmunity, patients with a history of allergic reactions, and individuals who are prone to develop autoimmunity (having a family history of autoimmune diseases; asymptomatic carriers of autoantibodies; carrying certain genetic profiles, etc.).
Study – Vaccines, adjuvants and autoimmunity.
Vaccines and autoimmunity are linked fields. Vaccine efficacy is based on whether host immune response against an antigen can elicit a memory T-cell response over time. Although the described side effects thus far have been mostly transient and acute, vaccines are able to elicit the immune system towards an autoimmune reaction. The diagnosis of a definite autoimmune disease and the occurrence of fatal outcome post-vaccination have been less frequently reported. Since vaccines are given to previously healthy hosts, who may have never developed the disease had they not been immunized, adverse events should be carefully accessed and evaluated even if they represent a limited number of occurrences. In this review of the literature, there is evidence of vaccine-induced autoimmunity and adjuvant-induced autoimmunity in both experimental models as well as human patients. Adjuvants and infectious agents may exert their immune-enhancing effects through various functional activities, encompassed by the adjuvant effect. These mechanisms are shared by different conditions triggered by adjuvants leading to the autoimmune/inflammatory syndrome induced by adjuvants (ASIA syndrome). In conclusion, there are several case reports of autoimmune diseases following vaccines, however, due to the limited number of cases, the different classifications of symptoms and the long latency period of the diseases, every attempt for an epidemiological study has so far failed to deliver a connection. Despite this, efforts to unveil the connection between the triggering of the immune system by adjuvants and the development of autoimmune conditions should be undertaken. Vaccinomics is a field that may bring to light novel customized, personalized treatment approaches in the future.
Study – On vaccine’s adjuvants and autoimmunity: Current evidence and future perspectives.
Adjuvants are compounds incorporated into vaccines to enhance immunogenicity and the development of these molecules has become an expanding field of research in the last decades. Adding an adjuvant to a vaccine antigen leads to several advantages, including dose sparing and the induction of a more rapid, broader and strong immune response. Several of these molecules have been approved, including aluminium salts, oil-in-water emulsions (MF59, AS03 and AF03), virosomes and AS04. Adjuvants have recently been implicated in the new syndrome named “ASIA-Autoimmune/inflammatory Syndrome Induced by Adjuvants”, which describes an umbrella of clinical conditions including post-vaccination adverse reactions. Recent studies implicate a web of mechanisms in the development of vaccine adjuvant-induced autoimmune diseases, in particular, in those associated with aluminium-based compounds. Fewer and unsystematised data are instead available about other adjuvants, despite recent evidence indicating that vaccines with different adjuvants may also cause specific autoimmune adverse reactions possible towards different pathogenic mechanisms. This topic is of importance as the specific mechanism of action of each single adjuvant may have different effects on the course of different diseases. Herein, we review the current evidence about the mechanism of action of currently employed adjuvants and discuss the mechanisms by which such components may trigger autoimmunity.