Vaccine News – VAXXED TV – A Certain Brightness and Intelligence & Study – Can Awareness of Medical Pathophysiology in Autism Lead to Primary Care Autism Prevention Strategies?

North American Journal of Medicine and Science – Jul 2013 Vol 6 No.3

Study – Can Awareness of Medical Pathophysiology in Autism Lead to Primary Care Autism Prevention Strategies?

Elizabeth Mumper, MD, FAAP*
2919 Confederate Avenue, Lynchburg, VA

Emerging research suggests that the timing of environmental factors in the presence of genetic predispositions has influenced the increase in autism spectrum disorders over the past several decades. A review of the medical literature suggests that autism may be impacted by environmental toxicants, breastfeeding duration, gut flora composition, nutritional status, acetaminophen use, vaccine practices and use of antibiotics and/or frequency of infections. The author reports her retrospective clinical research in a general pediatric practice (Advocates for Children), which shows a modest trend toward lower prevalence of autism than her previous pediatric practice or recent CDC data. Out of 294 general pediatrics patients followed since 2005 there were zero new cases of autism (p value 0.014). Given the prevalence of autism for that cohort of 1 in 50 children in the United States, it is important to consider implementing strategies in primary care practice that could potentially modify environmental factors or affect the timing of environmental triggers contributing to autism.

National Library of Medicine
National Institutes of Health – Jul 2009

Study – What is regressive autism and why does it occur? Is it the consequence of multi-systemic dysfunction affecting the elimination of heavy metals and the ability to regulate neural temperature?

Author information
Graham E. Ewing
Montague Healthcare, Mulberry House, 6 Vine Farm Close, Cotgrave, Nottingham NG12 3TU, United Kingdom

Abstract
There is a compelling argument that the occurrence of regressive autism is attributable to genetic and chromosomal abnormalities, arising from the overuse of vaccines, which subsequently affects the stability and function of the autonomic nervous system and physiological systems. That sense perception is linked to the autonomic nervous system and the function of the physiological systems enables us to examine the significance of autistic symptoms from a systemic perspective. Failure of the excretory system influences elimination of heavy metals and facilitates their accumulation and subsequent manifestation as neurotoxins: the long-term consequences of which would lead to neurodegeneration, cognitive and developmental problems. It may also influence regulation of neural hyperthermia. This article explores the issues and concludes that sensory dysfunction and systemic failure, manifested as autism, is the inevitable consequence arising from subtle DNA alteration and consequently from the overuse of vaccines.

Autistic disturbances of effective contact

Kanner L.
Johns Hopkins University

Case 3. Richard M. was referred to the Johns Hopkins Hospital on February 5, 1941, at 3 years, 3 months of age, with the complaint of deafness because he didnot talk and did not respond to questions.
Following smallpox vaccination at 12 months, he had an attack of diarrhea and fever, from which he recovered in somewhat less than a week
In september, 1940, the mother, in commenting on Richard’s failure to talk, remarked in her notes: I can’t be sure just when he stopped the imitation of wordssounds. It seems that he has gone backward mentally gradually for the last two years.
Richard M
November 1937 – Born
November 1938 – vaccinated with Smallpox vaccine
September 1940 – Mother reports developmental regression beginning approximately two years previously
February 1941 – Referred to Hopkins for evaluation
1943 – Becomes the third child to be described as autistic by Leo Kanner in his disorder defining paper, the first paper published on autism

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My unvaccinated extremely healthy children

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HPV Gardasil vaccine injured my daughter

A Certain Brightness and Intelligence

Vaccines injured my boy

Vaccinations gave my son autism

4 month vaccinations killed my baby

I will never vaccinate my family again

Dr Jeremy Kobler

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ONE FOR ISRAEL Ministry – Jewish Johnathan Ben-David forgave his killer and you would not believe why!!!

How to accept Jesus Christ as your personal Saviour

Testimony by Phil Robertson from Duck Dynasty

1 Corinthians 15 Authorized (King James) Version (AKJV)
1 Moreover, brethren, I declare unto you the gospel which I preached unto you, which also ye have received, and wherein ye stand;
2 by which also ye are saved, if ye keep in memory what I preached unto you, unless ye have believed in vain.
3 For I delivered unto you first of all that which I also received, how that Christ died for our sins according to the scriptures;
4 and that he was buried, and that he rose again the third day according to the scriptures:

Hebrews 6 Authorized (King James) Version (AKJV)
1 Therefore leaving the principles of the doctrine of Christ, let us go on unto perfection; not laying again the foundation of repentance from dead works, and of faith toward God,
2 of the doctrine of baptisms, and of laying on of hands, and of resurrection of the dead, and of eternal judgment.
3 And this will we do, if God permit.
4 For it is impossible for those who were once enlightened, and have tasted of the heavenly gift, and were made partakers of the Holy Ghost,
5 and have tasted the good word of God, and the powers of the world to come,
6 if they shall fall away, to renew them again unto repentance; seeing they crucify to themselves the Son of God afresh, and put him to an open shame.
7 For the earth which drinketh in the rain that cometh oft upon it, and bringeth forth herbs meet for them by whom it is dressed, receiveth blessing from God:
8 but that which beareth thorns and briers is rejected, and is nigh unto cursing; whose end is to be burned.

Isaiah 53 – Old testament Prophecy about Jesus

1 Who hath believed our report? and to whom is the arm of the Lord revealed?
2 For he shall grow up before him as a tender plant,and as a root out of a dry ground:he hath no form nor comeliness;and when we shall see him,there is no beauty that we should desire him.
3 He is despised and rejected of men;a man of sorrows, and acquainted with grief:and we hid as it were our faces from him;he was despised, and we esteemed him not.
4 Surely he hath borne our griefs,and carried our sorrows:yet we did esteem him stricken,smitten of God, and afflicted.
5 But he was wounded for our transgressions,he was bruised for our iniquities:the chastisement of our peace was upon him;and with his stripes we are healed.
6 All we like sheep have gone astray;we have turned every one to his own way;and the Lord hath laid on him the iniquity of us all.
7 He was oppressed, and he was afflicted,yet he opened not his mouth:he is brought as a lamb to the slaughter,and as a sheep before her shearers is dumb,so he openeth not his mouth.
8 He was taken from prison and from judgment:and who shall declare his generation? for he was cut off out of the land of the living:for the transgression of my people was he stricken.
9 And he made his grave with the wicked,and with the rich in his death;because he had done no violence,neither was any deceit in his mouth.
10 Yet it pleased the Lord to bruise him;he hath put him to grief:when thou shalt make his soul an offering for sin,he shall see his seed, he shall prolong his days,and the pleasure of the Lord shall prosper in his hand.
11 He shall see of the travail of his soul, and shall be satisfied:by his knowledge shall my righteous servant justify many;for he shall bear their iniquities.
12 Therefore will I divide him a portion with the great,and he shall divide the spoil with the strong;because he hath poured out his soul unto death:and he was numbered with the transgressors;and he bare the sin of many,and made intercession for the transgressors.

 

Vaccine News – VAXXED TV – DTaP vaccine gave my daughter epilepsy & Here’s Where the Aluminum from Vaccines Accumulates in the Body

Journal of Trace Elements in Medicine and Biology
Available online 26 November 2017

Study – Aluminium in brain tissue in autism
Matthew Mold – a, Dorcas Umar – b, Andrew King – c, Christopher Exley – a,

a The Birchall Centre, Lennard-Jones Laboratories, Keele University, Staffordshire, ST5 5BG, United Kingdom
b Life Sciences, Keele University, Staffordshire, ST5 5BG, United Kingdom
c Department of Clinical Neuropathology, Kings College Hospital, London, SE5 9RS, United Kingdom

Abstract
Autism spectrum disorder is a neurodevelopmental disorder of unknown aetiology. It is suggested to involve both genetic susceptibility and environmental factors including in the latter environmental toxins. Human exposure to the environmental toxin aluminium has been linked, if tentatively, to autism spectrum disorder. Herein we have used transversely heated graphite furnace atomic absorption spectrometry to measure, for the first time, the aluminium content of brain tissue from donors with a diagnosis of autism. We have also used an aluminium-selective fluor to identify aluminium in brain tissue using fluorescence microscopy. The aluminium content of brain tissue in autism was consistently high. The mean (standard deviation) aluminium content across all 5 individuals for each lobe were 3.82(5.42), 2.30(2.00), 2.79(4.05) and 3.82(5.17) μg/g dry wt. for the occipital, frontal, temporal and parietal lobes respectively. These are some of the highest values for aluminium in human brain tissue yet recorded and one has to question why, for example, the aluminium content of the occipital lobe of a 15 year old boy would be 8.74 (11.59) μg/g dry wt.? Aluminium-selective fluorescence microscopy was used to identify aluminium in brain tissue in 10 donors. While aluminium was imaged associated with neurones it appeared to be present intracellularly in microglia-like cells and other inflammatory non-neuronal cells in the meninges, vasculature, grey and white matter. The pre-eminence of intracellular aluminium associated with non-neuronal cells was a standout observation in autism brain tissue and may offer clues as to both the origin of the brain aluminium as well as a putative role in autism spectrum disorder.

US National Library of Medicine
National Institutes of Health – Oct 2012

Study – Relative trends in hospitalizations and mortality among infants by the number of vaccine doses and age, based on the Vaccine Adverse Event Reporting System (VAERS), 1990-2010.

Goldman GS, Miller NZ.
Author information
Computer Scientist, Pearblossom, CA 93553, USA. gsgoldman@roadrunner.com

Abstract
In this study, the Vaccine Adverse Event Reporting System (VAERS) database, 1990-2010, was investigated; cases that specified either hospitalization or death were identified among 38,801 reports of infants. Based on the types of vaccines reported, the actual number of vaccine doses administered, from 1 to 8, was summed for each case. Linear regression analysis of hospitalization rates as a function of (a) the number of reported vaccine doses and (b) patient age yielded a linear relationship with r(2) = 0.91 and r(2) = 0.95, respectively. The hospitalization rate increased linearly from 11.0% (107 of 969) for 2 doses to 23.5% (661 of 2817) for 8 doses and decreased linearly from 20.1% (154 of 765) for children aged <0.1 year to 10.7% (86 of 801) for children aged 0.9 year. The rate ratio (RR) of the mortality rate for 5-8 vaccine doses to 1-4 vaccine doses is 1.5 (95% confidence interval (CI), 1.4-1.7), indicating a statistically significant increase from 3.6% (95% CI, 3.2-3.9%) deaths associated with 1-4 vaccine doses to 5.5% (95% CI, 5.2-5.7%) associated with 5-8 vaccine doses. The male-to-female mortality RR was 1.4 (95% CI, 1.3-1.5). Our findings show a positive correlation between the number of vaccine doses administered and the percentage of hospitalizations and deaths. Since vaccines are given to millions of infants annually, it is imperative that health authorities have scientific data from synergistic toxicity studies on all combinations of vaccines that infants might receive. Finding ways to increase vaccine safety should be the highest priority.

Study – Aluminum in Vaccines Is Not Safe, According to Article in the Journal of American Physicians and Surgeons

The Association of American Physicians and Surgeons notes that, because of public concerns that mercury (as thimerosal) in childhood vaccines might be contributing to soaring rates of autism, this component was mostly phased out as a “precaution.” Autism rates continued to rise, prompting authorities to assert that autism is not linked to mercury in vaccines and that vaccination policies are safe and appropriate, writes Neil Z. Miller in the winter issue of the Journal of American Physicians and Surgeons.

ABSTRACT
Aluminum is a neurotoxin, yet infants and young children are repeatedly injected with aluminum adjuvants from multiple vaccines during critical periods of brain development. Numerous studies provide credible evidence that aluminum adversely affects important biological functions and may contribute to neurodegenerative and autoimmune disorders. It is impossible to predetermine which vaccinated babies will succumb to aluminum poisoning. Aluminum-free health options are needed.
PDF: http://www.jpands.org/vol21no4/miller.pdf

Discovery of “Shockingly High” Levels of Aluminum in Brains of Individuals with Autism Suggests Link with Aluminum-Containing Vaccines
Children medical safety research institute

Study Shows Evidence of Inflammatory Cells Loaded with Aluminum Crossing the Blood-Brain Barrier and Meningeal Membranes
(November 27, 2017) Staffordshire, UK — A new study published in the Journal of Trace Elements in Medicine and Biology provides the strongest indication yet that aluminum is an etiological agent in autism spectrum disorder (ASD), according to researchers at Keele University in England.
The study used transversely heated graphite furnace atomic absorption spectrometry to measure, for the first time, the aluminum content of brain tissue from five donors who had died with diagnoses of ASD. The results showed the donors to have had some of the highest values of aluminum yet measured in human brain tissue.
The mean (standard deviation) aluminum content across all five individuals for each lobe were 3.82(5.42), 2.30(2.00), 2.79(4.05) and 3.82(5.17) mg/g dry wt. for the occipital, frontal, temporal and parietal lobes respectively. Previous measurements of 60 brains from humans not diagnosed with ASD showed an average content of 1 mg/g dry wt. of brain tissue.
“One has to wonder why aluminum in the occipital lobe of a 15-year-old boy with autism would be a value that is at least 10 times higher than what might be considered acceptable for an elderly adult?” said Christopher Exley PhD, Professor in Bioinorganic Chemistry and author of the study. Another ground-breaking study by Exley and his team, published earlier in the year, identified similarly high levels of aluminum in the brains of individuals who died of familial Alzheimer’s disease.

Here’s Where the Aluminum from Vaccines Accumulates in the Body

When it comes to the most widely used adjuvant ingredient found within vaccines, aluminum, many questions have yet to be answered, particularly when it comes to where the aluminum goes after injection, an issue known as biopersistence.
One reason this question arises is because a causative role has been established in what’s known as macrophagic myofasciitis (MMF) lesion in patients who have myalgic encephalomyelitis, or brain inflammation. Myalgia, arthralgia, chronic fatigue, cognitive dysfunction, dysautonomia, and autoimmunity have been temporally linked to aluminium adjuvant-containing vaccine administration (Gherardi and Authier, 2003; Authier et al., 2003; Exley et al., 2009; Rosenblum et al., 2011; Santiago et al., 2014; Brinth et al., 2015; Palmieri et al., 2016).
“Evidence that aluminum-coated particles phagocytozed in the injected muscle and its draining lymph nodes can disseminate within phagocytes throughout the body and slowly accumulate in the brain further suggested that alum safety should be evaluated in the long term.”

US National Library of Medicine
National Institutes of Health – Jun 2015

Study – Fluorescent nanodiamonds as a relevant tag for the assessment of alum adjuvant particle biodisposition.

Eidi H – 1,2, David MO – 3, Crépeaux G – 4, Henry L – 5, Joshi V – 6, Berger MH – 7, Sennour M – 8, Cadusseau J – 9,10, Gherardi RK – 11, Curmi PA – 12.
Author information
1 Institut National de la Santé et de la Recherche Médicale (INSERM) – UMR 1204, Université Evry-Val d’Essonne, Laboratoire Structure-Activité des Biomolécules Normales et Pathologiques, Evry, France. housam.eidi@gmail.com.
2 Inserm – U955, Université Paris Est, Faculté de Médecine, Créteil, France. housam.eidi@gmail.com.
3 Institut National de la Santé et de la Recherche Médicale (INSERM) – UMR 1204, Université Evry-Val d’Essonne, Laboratoire Structure-Activité des Biomolécules Normales et Pathologiques, Evry, France. MO.David@iut.univ-evry.fr.
4 Inserm – U955, Université Paris Est, Faculté de Médecine, Créteil, France. guillemette.crepeaux@gmail.com.
5 Institut National de la Santé et de la Recherche Médicale (INSERM) – UMR 1204, Université Evry-Val d’Essonne, Laboratoire Structure-Activité des Biomolécules Normales et Pathologiques, Evry, France. laetitia.henry@wanadoo.fr.
6 Institut National de la Santé et de la Recherche Médicale (INSERM) – UMR 1204, Université Evry-Val d’Essonne, Laboratoire Structure-Activité des Biomolécules Normales et Pathologiques, Evry, France. vandana.joshi@univ-evry.fr.
7 Laboratoire Pierre-Marie Fourt, Centre des Matériaux de l’Ecole des Mines de Paris and CNRS UMR 7633, Evry, France. marie-helene.berger@mines-paristech.fr.
8 Laboratoire Pierre-Marie Fourt, Centre des Matériaux de l’Ecole des Mines de Paris and CNRS UMR 7633, Evry, France. mohamed.sennour@ensmp.fr.
9 Inserm – U955, Université Paris Est, Faculté de Médecine, Créteil, France. josette.cadusseau@inserm.fr.
10 Faculté des Sciences et Technologie UPEC, Créteil, France. josette.cadusseau@inserm.fr.
11 Inserm – U955, Université Paris Est, Faculté de Médecine, Créteil, France. romain.gherardi@hmn.aphp.fr.
12 Institut National de la Santé et de la Recherche Médicale (INSERM) – UMR 1204, Université Evry-Val d’Essonne, Laboratoire Structure-Activité des Biomolécules Normales et Pathologiques, Evry, France. pcurmi@univ-evry.fr.

Abstract

BACKGROUND:
Aluminum oxyhydroxide (alum) is a crystalline compound widely used as an immunologic adjuvant of vaccines. Concerns linked to alum particles have emerged following recognition of their causative role in the so-called macrophagic myofasciitis (MMF) lesion in patients with myalgic encephalomyelitis, revealing an unexpectedly long-lasting biopersistence of alum within immune cells and a fundamental misconception of its biodisposition. Evidence that aluminum-coated particles phagocytozed in the injected muscle and its draining lymph nodes can disseminate within phagocytes throughout the body and slowly accumulate in the brain further suggested that alum safety should be evaluated in the long term. However, lack of specific staining makes difficult the assessment of low quantities of bona fide alum adjuvant particles in tissues.

METHODS:
We explored the feasibility of using fluorescent functionalized nanodiamonds (mfNDs) as a permanent label of alum (Alhydrogel(®)). mfNDs have a specific and perfectly photostable fluorescence based on the presence within the diamond lattice of nitrogen-vacancy centers (NV centers). As the NV center does not bleach, it allows the microspectrometric detection of mfNDs at very low levels and in the long-term. We thus developed fluorescent nanodiamonds functionalized by hyperbranched polyglycerol (mfNDs) allowing good coupling and stability of alum:mfNDs (AluDia) complexes. Specificities of AluDia complexes were comparable to the whole reference vaccine (anti-hepatitis B vaccine) in terms of particle size and zeta potential.

RESULTS:
In vivo, AluDia injection was followed by prompt phagocytosis and AluDia particles remained easily detectable by the specific signal of the fND particles in the injected muscle, draining lymph nodes, spleen, liver and brain. In vitro, mfNDs had low toxicity on THP-1 cells and AluDia showed cell toxicity similar to alum alone. Expectedly, AluDia elicited autophagy, and allowed highly specific detection of small amounts of alum in autophagosomes.

CONCLUSIONS:
The fluorescent nanodiamond technology is able to overcome the limitations of previously used organic fluorophores, thus appearing as a choice methodology for studying distribution, persistence and long-term neurotoxicity of alum adjuvants and beyond of other types of nanoparticles.

VAXXED TV – Vaccines gave my son autism

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Health professionals talk vaccinations

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3 months ago my baby died following vaccinations

My 2 children have autism from vaccines

DTaP vaccine gave my daughter epilepsy

****************************************************

ONE FOR ISRAEL Ministry – Jewish Johnathan Ben-David forgave his killer and you would not believe why!!!

How to accept Jesus Christ as your personal Saviour

Testimony by Phil Robertson from Duck Dynasty

1 Corinthians 15 Authorized (King James) Version (AKJV)
1 Moreover, brethren, I declare unto you the gospel which I preached unto you, which also ye have received, and wherein ye stand;
2 by which also ye are saved, if ye keep in memory what I preached unto you, unless ye have believed in vain.
3 For I delivered unto you first of all that which I also received, how that Christ died for our sins according to the scriptures;
4 and that he was buried, and that he rose again the third day according to the scriptures:

Hebrews 6 Authorized (King James) Version (AKJV)
1 Therefore leaving the principles of the doctrine of Christ, let us go on unto perfection; not laying again the foundation of repentance from dead works, and of faith toward God,
2 of the doctrine of baptisms, and of laying on of hands, and of resurrection of the dead, and of eternal judgment.
3 And this will we do, if God permit.
4 For it is impossible for those who were once enlightened, and have tasted of the heavenly gift, and were made partakers of the Holy Ghost,
5 and have tasted the good word of God, and the powers of the world to come,
6 if they shall fall away, to renew them again unto repentance; seeing they crucify to themselves the Son of God afresh, and put him to an open shame.
7 For the earth which drinketh in the rain that cometh oft upon it, and bringeth forth herbs meet for them by whom it is dressed, receiveth blessing from God:
8 but that which beareth thorns and briers is rejected, and is nigh unto cursing; whose end is to be burned.

Isaiah 53 – Old testament Prophecy about Jesus

1 Who hath believed our report? and to whom is the arm of the Lord revealed?
2 For he shall grow up before him as a tender plant,and as a root out of a dry ground:he hath no form nor comeliness;and when we shall see him,there is no beauty that we should desire him.
3 He is despised and rejected of men;a man of sorrows, and acquainted with grief:and we hid as it were our faces from him;he was despised, and we esteemed him not.
4 Surely he hath borne our griefs,and carried our sorrows:yet we did esteem him stricken,smitten of God, and afflicted.
5 But he was wounded for our transgressions,he was bruised for our iniquities:the chastisement of our peace was upon him;and with his stripes we are healed.
6 All we like sheep have gone astray;we have turned every one to his own way;and the Lord hath laid on him the iniquity of us all.
7 He was oppressed, and he was afflicted,yet he opened not his mouth:he is brought as a lamb to the slaughter,and as a sheep before her shearers is dumb,so he openeth not his mouth.
8 He was taken from prison and from judgment:and who shall declare his generation? for he was cut off out of the land of the living:for the transgression of my people was he stricken.
9 And he made his grave with the wicked,and with the rich in his death;because he had done no violence,neither was any deceit in his mouth.
10 Yet it pleased the Lord to bruise him;he hath put him to grief:when thou shalt make his soul an offering for sin,he shall see his seed, he shall prolong his days,and the pleasure of the Lord shall prosper in his hand.
11 He shall see of the travail of his soul, and shall be satisfied:by his knowledge shall my righteous servant justify many;for he shall bear their iniquities.
12 Therefore will I divide him a portion with the great,and he shall divide the spoil with the strong;because he hath poured out his soul unto death:and he was numbered with the transgressors;and he bare the sin of many,and made intercession for the transgressors.

 

Vaccine News – VAXXED TV – Vaccines injured my son & Study – Thiol-modulated mechanisms of the cytotoxicity of thimerosal and inhibition of DNA topoisomerase II alpha

US National Library of Medicine
National Institutes of Health – Feb 2012

Study – Mechanisms of aluminum adjuvant toxicity and autoimmunity in pediatric populations.

Tomljenovic L, Shaw CA.
Author information
Neural Dynamics Research Group, Department of Ophthalmology and Visual Sciences, University of British Columbia, Vancouver, BC, Canada. lucijat77@gmail.com

Abstract
Immune challenges during early development, including those vaccine-induced, can lead to permanent detrimental alterations of the brain and immune function. Experimental evidence also shows that simultaneous administration of as little as two to three immune adjuvants can overcome genetic resistance to autoimmunity. In some developed countries, by the time children are 4 to 6 years old, they will have received a total of 126 antigenic compounds along with high amounts of aluminum (Al) adjuvants through routine vaccinations. According to the US Food and Drug Administration, safety assessments for vaccines have often not included appropriate toxicity studies because vaccines have not been viewed as inherently toxic. Taken together, these observations raise plausible concerns about the overall safety of current childhood vaccination programs. When assessing adjuvant toxicity in children, several key points ought to be considered: (i) infants and children should not be viewed as “small adults” with regard to toxicological risk as their unique physiology makes them much more vulnerable to toxic insults; (ii) in adult humans Al vaccine adjuvants have been linked to a variety of serious autoimmune and inflammatory conditions (i.e., “ASIA”), yet children are regularly exposed to much higher amounts of Al from vaccines than adults; (iii) it is often assumed that peripheral immune responses do not affect brain function. However, it is now clearly established that there is a bidirectional neuro-immune cross-talk that plays crucial roles in immunoregulation as well as brain function. In turn, perturbations of the neuro-immune axis have been demonstrated in many autoimmune diseases encompassed in “ASIA” and are thought to be driven by a hyperactive immune response; and (iv) the same components of the neuro-immune axis that play key roles in brain development and immune function are heavily targeted by Al adjuvants. In summary, research evidence shows that increasing concerns about current vaccination practices may indeed be warranted. Because children may be most at risk of vaccine-induced complications, a rigorous evaluation of the vaccine-related adverse health impacts in the pediatric population is urgently needed.

The spectrum of ASIA: ‘Autoimmune (Auto-inflammatory) Syndrome induced by Adjuvants’

Sage journals – 1 Feb 2012

N Agmon-Levin – 1, GRV Hughes – 2, Y Shoenfeld1 – 3
1 – The Zabludowicz Center for Autoimmune Diseases, Sheba Medical Center, Tel-Hashomer, Israel
2 – Head, Lupus Research Unit, The Rayne Institute, St. Thomas’ Hospital, London, UK
3 – Sackler Faculty of Medicine, Incumbent of the Laura Schwarz-KipChair for Research of Autoimmune Diseases, Tel-Aviv University, Israel
Corresponding Author: Yehuda Shoenfeld, MD, FRCP, Zabludowicz Center for Autoimmune Diseases, Chaim Sheba Medical Center, Tel-Hashomer 52621, Israel. Email: shoenfel@post.tau.ac.il

Another cornerstone of ASIA is the complex interaction between autoimmunity and adjuvanted vaccines. On the one hand vaccines are beneficial for the vast majority of subjects including those who suffer from autoimmune-rheumatic diseases as delineated in this issue by van Assen and Bijl.16 On the other hand in a small minority of individuals vaccine can trigger the appearance of autoantibodies as documented by Vista et al.17 and Perdan-Pirkmajer et al.18 Moreover, a link between immunization and defined autoimmune diseases has been reported elsewhere and herein.2 A plausible association between the flu vaccine and polymyalgia rheumatica is reported here by Soriano et al.19 from Italy, and Soldevilla et al.20 describe three patients diagnosed with SLE following immunization with the human papilloma vaccine from the Philippines. In addition, in a retrospective analysis Zafrir et al.21 details common denominators among 93 American patients diagnosed with immune-mediated conditions following inoculation with hepatitis B vaccine. In this cohort although different autoimmune diseases were diagnosed, many manifestation were common to all patients and 86% of them fulfilled the criteria for ASIA. Of note, these cohorts signify only one side of the ASIA spectrum as they cope with distinct immune-mediated diseases while ASIA also comprises enigmatic and non-defined medical conditions. Two such conditions, the macrophagic myofasciitic syndrome and the Gulf War syndrome, are thus reviewed in this special issue by Gherardi and Authier22 and Israeli.23

Study – Etiology of autism spectrum disorders: Genes, environment, or both?

C Shaw, S Sheth, D Li, L Tomljenovic

Authors affiliations
University of British Columbia, Vancouver, British Columbia, Canada

Abstract
Thus far, most of the research on both neurodevelopmental and neurodegenerative disorders has been focused on finding the presumed underlying genetic causes, while much less emphasis has been put on potential environmental factors. While some forms of autism are clearly genetic, the fact remains that heritability factors cannot adequately explain all reported cases nor their drastic increase over the last few decades. In particular, studies on twins have now shown that common environmental factors account for 55% of their risk for developing autism while genetic susceptibility explains only 37% of cases. Because the prenatal environment and early postnatal environment are shared between twins and because overt symptoms of autism emerge around the end of the first year of life, it is likely that at least some of the environmental factors contributing to the risk of autism exert their deleterious neurodevelopmental effect during this early period of life. Indeed, evidence has now emerged showing that autism may in part result from early-life immune insults induced by environmental xenobiotics. One of the most common xenobiotic with immuno-stimulating as well as neurotoxic properties to which infants under two years of age are routinely exposed worldwide is the aluminum (Al) vaccine adjuvant. In this review we discuss the mechanisms by which Al can induce adverse neurological and immunological effects and how these may provide important clues of Al’s putative role in autism. Because of the tight connection between the development of the immune and the central nervous system, the possibility that immune-overstimulation in early infancy via vaccinations may play a role in neurobehavioural disorders needs to be carefully considered.

Conclusion
There is now sufficient evidence from both human and animal studies showing that cumulative exposure to aluminium adjuvants is not as benign as previously assumed. Given that vaccines are the only medical intervention that we attempt to deliver to every living human on earth and that by far the largest target population for vaccination are healthy children, a better appreciation and understanding of vaccine adjuvant risks appears warranted.

US National Library of Medicine
National Institutes of Health – Feb 2008

Study – Thiol-modulated mechanisms of the cytotoxicity of thimerosal and inhibition of DNA topoisomerase II alpha.

Wu X1, Liang H, O’Hara KA, Yalowich JC, Hasinoff BB.
Author information
Faculty of Pharmacy, University of Manitoba, 50 Sifton Road, Winnipeg, Manitoba, R3T 2N2, Canada.

Abstract
Thimerosal is an organic mercury compound that is widely used as a preservative in vaccines and other solution formulations. The use of thimerosal has caused concern about its ability to cause neurological abnormalities due to mercury accumulation during a normal schedule of childhood vaccinations. While the chemistry and the biological effects of methylmercury have been well-studied, those of thimerosal have not. Thimerosal reacted rapidly with cysteine, GSH, human serum albumin, and single-stranded DNA to form ethylmercury adducts that were detectable by mass spectrometry. These results indicated that thimerosal would be quickly metabolized in vivo because of its reactions with protein and nonprotein thiols. Thimerosal also potently inhibited the decatenation activity of DNA topoisomerase II alpha, likely through reaction with critical free cysteine thiol groups. Thimerosal, however, did not act as a topoisomerase II poison and the lack of cross-resistance with a K562 cell line with a decreased level of topoisomerase II alpha (K/VP.5 cells) suggested that inhibition of topoisomerase II alpha was not a significant mechanism for the inhibition of cell growth. Depletion of intracellular GSH with buthionine sulfoximine treatment greatly increased the K562 cell growth inhibitory effects of thimerosal, which showed that intracellular glutathione had a major role in protecting cells from thimerosal. Pretreatment of thimerosal with glutathione did not, however, change its K562 cell growth inhibitory effects, a result consistent with the rapid exchange of the ethylmercury adduct among various thiol-containing cellular reactants. Thimerosal-induced single and double strand breaks in K562 cells were consistent with a rapid induction of apoptosis. In conclusion, these studies have elucidated some of the chemistry and biological activities of the interaction of thimerosal with topoisomerase II alpha and protein and nonprotein thiols and with DNA.

VAXXED TV – My daughter is unvaccinated and very healthy

Vaccines injured my son

Our doctor fired us

My grandson has autism from vaccines

My children are injured by vaccines

College vaccinations destroyed everything I was going to do

Just saying Hi!

Vaccines killed my grandson

Linda Tells about her children and difficulties dealing with medical professionals
Linda speaks about her children’s reactions to vaccinations, the troubles with school officials and medical professionals.

Mother speaks about her daughter’s reaction to MR
Mother speaks at great length about her daughter’s progress through life as she develops illnesses as a result of 2 vaccine shots given at school

Vaxxed versus unvaxxed

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ONE FOR ISRAEL Ministry – Jewish Johnathan Ben-David forgave his killer and you would not believe why!!!

How to accept Jesus Christ as your personal Saviour

Testimony by Phil Robertson from Duck Dynasty

1 Corinthians 15 Authorized (King James) Version (AKJV)
1 Moreover, brethren, I declare unto you the gospel which I preached unto you, which also ye have received, and wherein ye stand;
2 by which also ye are saved, if ye keep in memory what I preached unto you, unless ye have believed in vain.
3 For I delivered unto you first of all that which I also received, how that Christ died for our sins according to the scriptures;
4 and that he was buried, and that he rose again the third day according to the scriptures:

Hebrews 6 Authorized (King James) Version (AKJV)
1 Therefore leaving the principles of the doctrine of Christ, let us go on unto perfection; not laying again the foundation of repentance from dead works, and of faith toward God,
2 of the doctrine of baptisms, and of laying on of hands, and of resurrection of the dead, and of eternal judgment.
3 And this will we do, if God permit.
4 For it is impossible for those who were once enlightened, and have tasted of the heavenly gift, and were made partakers of the Holy Ghost,
5 and have tasted the good word of God, and the powers of the world to come,
6 if they shall fall away, to renew them again unto repentance; seeing they crucify to themselves the Son of God afresh, and put him to an open shame.
7 For the earth which drinketh in the rain that cometh oft upon it, and bringeth forth herbs meet for them by whom it is dressed, receiveth blessing from God:
8 but that which beareth thorns and briers is rejected, and is nigh unto cursing; whose end is to be burned.

Isaiah 53 – Old testament Prophecy about Jesus

1 Who hath believed our report? and to whom is the arm of the Lord revealed?
2 For he shall grow up before him as a tender plant,and as a root out of a dry ground:he hath no form nor comeliness;and when we shall see him,there is no beauty that we should desire him.
3 He is despised and rejected of men;a man of sorrows, and acquainted with grief:and we hid as it were our faces from him;he was despised, and we esteemed him not.
4 Surely he hath borne our griefs,and carried our sorrows:yet we did esteem him stricken,smitten of God, and afflicted.
5 But he was wounded for our transgressions,he was bruised for our iniquities:the chastisement of our peace was upon him;and with his stripes we are healed.
6 All we like sheep have gone astray;we have turned every one to his own way;and the Lord hath laid on him the iniquity of us all.
7 He was oppressed, and he was afflicted,yet he opened not his mouth:he is brought as a lamb to the slaughter,and as a sheep before her shearers is dumb,so he openeth not his mouth.
8 He was taken from prison and from judgment:and who shall declare his generation? for he was cut off out of the land of the living:for the transgression of my people was he stricken.
9 And he made his grave with the wicked,and with the rich in his death;because he had done no violence,neither was any deceit in his mouth.
10 Yet it pleased the Lord to bruise him;he hath put him to grief:when thou shalt make his soul an offering for sin,he shall see his seed, he shall prolong his days,and the pleasure of the Lord shall prosper in his hand.
11 He shall see of the travail of his soul, and shall be satisfied:by his knowledge shall my righteous servant justify many;for he shall bear their iniquities.
12 Therefore will I divide him a portion with the great,and he shall divide the spoil with the strong;because he hath poured out his soul unto death:and he was numbered with the transgressors;and he bare the sin of many,and made intercession for the transgressors.

 

Vaccine News – VAXXED TV – I now realize the danger of vaccinations & Study – Infant mortality rates regressed against number of vaccine doses routinely given: Is there a biochemical or synergistic toxicity?

US National Library of Medicine
National Institutes of Health – Jan 2009

Study – Do childhood vaccines cause thrombocytopenia?
Laura J Sauvé, MD MPH and David Scheifele, MD
Vaccine Evaluation Centre, BC Children’s Hospital, Vancouver, British Columbia
Correspondence: Dr Laura Sauvé, Vaccine Evaluation Centre, Shaughnessy Site, Room L427, 4500 Oak Street, Vancouver, British Columbia

An increasing body of evidence has been gathered since the mid-1960s to support a link between vaccinations, particularly the measles-mumps-rubella (MMR) vaccine and idiopathic thrombocytopenic purpura (ITP). The incidence rate is estimated to be between one in 25,000 to one in 40,000 doses of MMR (1,2); this is much less frequent than after natural infection with measles (common), rubella (one in 3000 cases) and varicella. The purpose of the present commentary is to review vaccine-associated thrombocytopenia (VATP).
Vaccine-preventable diseases are becoming rare in Canada, with an average of 10 reported cases of measles per year between 2002 and 2006; although there was a large outbreak in Quebec in 2007, with 95 confirmed cases (3). With widespread vaccination and the near disappearance of vaccine-preventable diseases in Canada, there is less societal tolerance for adverse events following immunization (AEFI). One of the challenges in assessing AEFIs is distinguishing events that are causally linked with vaccination from those that are only temporally associated. Cases of thrombocytopenia in the first month after vaccination often have a history of recent viral infection or coadministration of medications that may also lead to thrombocytopenia, making the actual cause of VATP difficult to identify.
Since 1992, the Immunization Monitoring Program, ACTive (IMPACT), conducted by the Canadian Paediatric Society, has performed active surveillance for children who are hospitalized with AEFIs, including VATP. Trained nurse monitors at each of the 12 IMPACT centres review all admissions for children admitted for VATP (children with a platelet count of less than 100×109/L and no obvious other cause, such as cancer chemotherapy) within one month of documented receipt of any vaccine. Jadavji et al (4) reported on the first nine years of surveillance (with 61 cases) for VATP in 2003. One of the limitations in the IMPACT data is that detecting a case requires the treating physician to document administration of a vaccine in the previous month (the nurse monitors do not interview the parents). A recent American study (1) found that treating physicians had asked only two of 13 children with VATP about recent vaccination.
The IMPACT data on VATP are similar to reports from other countries, including the United Kingdom, France and the United States (1,2,5,6). In Canada, 103 cases of VATP have been documented by IMPACT since 1992 (7). The median age was 13 months, and 61% of those affected were boys. Petechial rash and bruising were the typical presenting signs. Most (73%) cases were treated with intravenous immunoglobulin. Most children did quite well, with rapid recovery; only six of 95 children with follow-up data still had abnormal platelet counts after three months. However, two children had severe bleeding-related complications, one had a gastrointestinal bleed requiring intensive care and one had post-traumatic intracranial bleeding leading to death.
Most cases of VATP are associated with MMR or measles vaccine, including 72% of the cases reported to IMPACT (25 of these 74 children had received one or more additional vaccines, including 10 children who also received the diphtheria, pertussis and tetanus vaccine, and 10 children who had received the varicella vaccine). Of the children who had MMR associated with thrombocytopenia in the IMPACT study, nine (12%) had a previous recorded dose of the vaccine without known thrombocytopenia. When all of the VATP cases were considered, 31% of the VATP episodes occurred after the second or third exposure to a vaccine.

US National Library of Medicine
National Institutes of Health – Sep 2011

Study – Infant mortality rates regressed against number of vaccine doses routinely given: Is there a biochemical or synergistic toxicity?

Abstract

The infant mortality rate (IMR) is one of the most important indicators of the socio-economic well-being and public health conditions of a country. The US childhood immunization schedule specifies 26 vaccine doses for infants aged less than 1 year—the most in the world—yet 33 nations have lower IMRs. Using linear regression, the immunization schedules of these 34 nations were examined and a correlation coefficient of r = 0.70 (p < 0.0001) was found between IMRs and the number of vaccine doses routinely given to infants. Nations were also grouped into five different vaccine dose ranges: 12–14, 15–17, 18–20, 21–23, and 24–26. The mean IMRs of all nations within each group were then calculated. Linear regression analysis of unweighted mean IMRs showed a high statistically significant correlation between increasing number of vaccine doses and increasing infant mortality rates, with r = 0.992 (p = 0.0009). Using the Tukey-Kramer test, statistically significant differences in mean IMRs were found between nations giving 12–14 vaccine doses and those giving 21–23, and 24–26 doses. A closer inspection of correlations between vaccine doses, biochemical or synergistic toxicity, and IMRs is essential.

Are flu vaccines risking senior citizens’ lives? Some say Yes.

A buried JAMA study from almost a decade ago which showed that there was no improvement in mortality rates among senior citizens with a flu vaccine, even after greatly increased vaccination rates. The study “got little attention,” she says, “because the science came down on the wrong side.” Whereas the researchers had set out to prove that the push for massive flu vaccination would save the world, the researchers were “astonished” to find that the data did not support their presupposition at all. The data actually shows that deaths increased, not decreased, among seniors following vaccination.
Johns Hopkins scientist, Peter Doshi, Ph.D., issued a report in the prestigious British Medical Journal, according to NewsLI, asserting that the CDC policy of routinely recommending the flu vaccine is being based on “low quality studies that do not substantiate claims.” He says there is no evidence that the vaccine reduces deaths among senior citizens. Interestingly, Doshi cites an Australian study which found significant risks for children as well, stating that “one in every 110 children under the age of five had convulsions following vaccinations in 2009 for H1N1 influenza.”
During the drug trials for the Fluzone flu vaccine, 23 seniors out of 3,833 died after receiving the shot, according to the drug’s package insert, reported by Health Impact News. Another 226 experienced “serious adverse effects.” The manufacturer denies any connection between the deaths and the flu vaccine.

JAMA internal medicine – 14 Feb 2005

Study – Impact of Influenza Vaccination on Seasonal Mortality in the US Elderly Population

Lone Simonsen, PhD; Thomas A. Reichert, MD, PhD; Cecile Viboud, PhD;

Abstract

Background Observational studies report that influenza vaccination reduces winter mortality risk from any cause by 50% among the elderly. Influenza vaccination coverage among elderly persons (≥65 years) in the United States increased from between 15% and 20% before 1980 to 65% in 2001. Unexpectedly, estimates of influenza-related mortality in this age group also increased during this period. We tried to reconcile these conflicting findings by adjusting excess mortality estimates for aging and increased circulation of influenza A(H3N2) viruses.

Methods We used a cyclical regression model to generate seasonal estimates of national influenza-related mortality (excess mortality) among the elderly in both pneumonia and influenza and all-cause deaths for the 33 seasons from 1968 to 2001. We stratified the data by 5-year age group and separated seasons dominated by A(H3N2) viruses from other seasons.

Results For people aged 65 to 74 years, excess mortality rates in A(H3N2)-dominated seasons fell between 1968 and the early 1980s but remained approximately constant thereafter. For persons 85 years or older, the mortality rate remained flat throughout. Excess mortality in A(H1N1) and B seasons did not change. All-cause excess mortality for persons 65 years or older never exceeded 10% of all winter deaths.

Conclusions We attribute the decline in influenza-related mortality among people aged 65 to 74 years in the decade after the 1968 pandemic to the acquisition of immunity to the emerging A(H3N2) virus. We could not correlate increasing vaccination coverage after 1980 with declining mortality rates in any age group. Because fewer than 10% of all winter deaths were attributable to influenza in any season, we conclude that observational studies substantially overestimate vaccination benefit.

VAXXED TV – Military vaccines made me sick

I Slept My Teenage Years AWAY!
Kelly recalls life before and after given vaccines during a swine flu epidemic.
Interview recorded on May 5th, 2017 in The United Kingdom

People need to WAKE UP!
Angela tells her story about her children and her foundation to help others in her area.
Interview recorded on May 5th, 2017 in The United Kingdom

TDap made my husband sick

Vaccinated versus unvaccinated

I now realize the danger of vaccinations

I was a scientist and will now never vaccinate my children

Vaccines gave my son autism

My 3 children are injured from vaccines

I am injured so I will never vaccinate my children

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How to accept Jesus Christ as your personal Saviour

Testimony by Phil Robertson from Duck Dynasty

1 Corinthians 15 Authorized (King James) Version (AKJV)
1 Moreover, brethren, I declare unto you the gospel which I preached unto you, which also ye have received, and wherein ye stand;
2 by which also ye are saved, if ye keep in memory what I preached unto you, unless ye have believed in vain.
3 For I delivered unto you first of all that which I also received, how that Christ died for our sins according to the scriptures;
4 and that he was buried, and that he rose again the third day according to the scriptures:

Hebrews 6 Authorized (King James) Version (AKJV)
1 Therefore leaving the principles of the doctrine of Christ, let us go on unto perfection; not laying again the foundation of repentance from dead works, and of faith toward God,
2 of the doctrine of baptisms, and of laying on of hands, and of resurrection of the dead, and of eternal judgment.
3 And this will we do, if God permit.
4 For it is impossible for those who were once enlightened, and have tasted of the heavenly gift, and were made partakers of the Holy Ghost,
5 and have tasted the good word of God, and the powers of the world to come,
6 if they shall fall away, to renew them again unto repentance; seeing they crucify to themselves the Son of God afresh, and put him to an open shame.
7 For the earth which drinketh in the rain that cometh oft upon it, and bringeth forth herbs meet for them by whom it is dressed, receiveth blessing from God:
8 but that which beareth thorns and briers is rejected, and is nigh unto cursing; whose end is to be burned.

 

Vaccine News – Study – Thimerosal exposure in infants and neurodevelopmental disorders: an assessment of computerized medical records in the Vaccine Safety Datalink & VAXXED TV – My vaccinated injured family

A study published in the Journal of Toxicology and Environmental Health determined that mercury exposure can induce immune, sensory, neurological, motor and behavioural dysfunctions similar to traits defining or associated with ASDs. Based upon differential diagnoses, 8 of 9 patients examined were exposed to significant mercury from Thimerosal-containing vaccine preparations during their fetal/infant developmental periods. These previously normal developing children suffered mercury encephalopathies that manifested with clinical symptoms consistent with regressive ASDs. Evidence for mercury intoxication should be considered in the differential diagnosis as contributing to some regressive ASDs.

US National Library of Medicine
National Institutes of Health – May 2007

Study – A case series of children with apparent mercury toxic encephalopathies manifesting with clinical symptoms of regressive autistic disorders

Geier DA, Geier MR.
Author information
Institute of Chronic Illnesses, Inc., Silver Spring, Maryland, USA.

Abstract
Impairments in social relatedness and communication, repetitive behaviors, and stereotypic abnormal movement patterns characterize autism spectrum disorders (ASDs). It is clear that while genetic factors are important to the pathogenesis of ASDs, mercury exposure can induce immune, sensory, neurological, motor, and behavioral dysfunctions similar to traits defining or associated with ASDs. The Institutional Review Board of the Institute for Chronic Illnesses (Office for Human Research Protections, U.S. Department of Health and Human Services, IRB number IRB00005375) approved the present study. A case series of nine patients who presented to the Genetic Centers of America for a genetic/developmental evaluation are discussed. Eight of nine patients (one patient was found to have an ASD due to Rett’s syndrome) (a) had regressive ASDs; (b) had elevated levels of androgens; (c) excreted significant amounts of mercury post chelation challenge; (d) had biochemical evidence of decreased function in their glutathione pathways; (e) had no known significant mercury exposure except from Thimerosal-containing vaccines/Rho(D)-immune globulin preparations; and (f) had alternate causes for their regressive ASDs ruled out. There was a significant dose-response relationship between the severity of the regressive ASDs observed and the total mercury dose children received from Thimerosal-containing vaccines/Rho (D)-immune globulin preparations. Based upon differential diagnoses, 8 of 9 patients examined were exposed to significant mercury from Thimerosal-containing biologic/vaccine preparations during their fetal/infant developmental periods, and subsequently, between 12 and 24 mo of age, these previously normally developing children suffered mercury toxic encephalopathies that manifested with clinical symptoms consistent with regressive ASDs. Evidence for mercury intoxication should be considered in the differential diagnosis as contributing to some regressive ASDs.

A study conducted by the Department of Obstetrics and Gynaecology at University of Pittsburgh’s School of Medicine showed that Macaques are commonly used in pre-clinical vaccine safety testing. Collective Evolution does not support animals testing, we feel there is a large amount of evidence and research that already indicated the links to vaccines in which some animals have been used to illustrate. The objective of this study was to compare early infant cognition and behaviour with amygdala size and opioid binding in rhesus macaques receiving the recommended childhood vaccines. The animal model, which examines for the first time, behavioural, functional and neuromorphometric consequences of the childhood vaccine regimen, mimics certain neurological abnormalities of autism. These findings raise important safety issues while providing a potential model for examining aspects of causation and disease pathogenesis in acquired disorders of behaviour and development.

Neurobiologiae experimentalis – 2010

Study – Influence of pediatric vaccines on amygdala growth and opioid ligand binding in rhesus macaque infants: A pilot study

Author information
Laura Hewitson – 1,2,*, Brian J. Lopresti – 3, Carol Stott – 4, N. Scott Mason – 3 and Jaime Tomko – 1
1 Department of Obstetrics and Gynecology, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA;
2 Thoughtful House Center for Children, Austin, TX, USA;
3 Department of Radiology, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA;
4 Independent Chartered Scientist, Cambridge, UK;

Abstract
This longitudinal, case-control pilot study examined amygdala growth in rhesus macaque infants receiving the complete US childhood vaccine schedule (1994-1999). Longitudinal structural and functional neuroimaging was undertaken to examine central effects of the vaccine regimen on the developing brain. Vaccine-exposed and saline-injected control infants underwent MRI and PET imaging at approximately 4 and 6 months of age, representing two specific timeframes within the vaccination schedule. Volumetric analyses showed that exposed animals did not undergo the maturational changes over time in amygdala volume that was observed in unexposed animals. After controlling for left amygdala volume, the binding of the opioid antagonist [11C]diprenorphine (DPN) in exposed animals remained relatively constant over time, compared with unexposed animals, in which a significant decrease in [11C]DPN binding occurred. These results suggest that maturational changes in amygdala volume and the binding capacity of [11C]DPN in the amygdala was significantly altered in infant macaques receiving the vaccine schedule. The macaque infant is a relevant animal model in which to investigate specific environmental exposures and structural/functional neuroimaging during neurodevelopment.

A study conducted by The George Washington University School of Public Health from the Department of Epidemiology and Biostatistics determined that significantly increased rate ratios were observed for autism and autism spectrum disorders as a result of exposure to mercury from Thimerosal-containing vaccines.

US National Library of Medicine
National Institutes of Health – Aug 2008

Study – Thimerosal exposure in infants and neurodevelopmental disorders: an assessment of computerized medical records in the Vaccine Safety Datalink

Young HA, Geier DA, Geier MR.
Author information
The George Washington University School of Public Health and Health Services, Department of Epidemiology and Biostatistics, United States.

Abstract
The study evaluated possible associations between neurodevelopmental disorders (NDs) and exposure to mercury (Hg) from Thimerosal-containing vaccines (TCVs) by examining the automated Vaccine Safety Datalink (VSD). A total of 278,624 subjects were identified in birth cohorts from 1990-1996 that had received their first oral polio vaccination by 3 months of age in the VSD. The birth cohort prevalence rate of medically diagnosed International Classification of Disease, 9th revision (ICD-9) specific NDs and control outcomes were calculated. Exposures to Hg from TCVs were calculated by birth cohort for specific exposure windows from birth-7 months and birth-13 months of age. Poisson regression analysis was used to model the association between the prevalence of outcomes and Hg doses from TCVs. Consistent significantly increased rate ratios were observed for autism, autism spectrum disorders, tics, attention deficit disorder, and emotional disturbances with Hg exposure from TCVs. By contrast, none of the control outcomes had significantly increased rate ratios with Hg exposure from TCVs. Routine childhood vaccination should be continued to help reduce the morbidity and mortality associated with infectious diseases, but efforts should be undertaken to remove Hg from vaccines. Additional studies should be conducted to further evaluate the relationship between Hg exposure and NDs.

 

 

 

VAXXED TV – My Vaxxed child versus my unvaccinated child

My super healthy unvaccinated Children

 

 

Hep B and vit K made my baby sick

 

My vaccinated injured family

Vaxxed versus unvaccinated in my family

My children are unvaccinated and perfect

My unvaccinated healthy girl

I did not vaccinate my adopted children

We will never vaccinate again

Tidal wave of vaccine injury

****************************************************

How to accept Jesus Christ as your personal Saviour

Testimony by Phil Robertson from Duck Dynasty

1 Corinthians 15 Authorized (King James) Version (AKJV)
1 Moreover, brethren, I declare unto you the gospel which I preached unto you, which also ye have received, and wherein ye stand;
2 by which also ye are saved, if ye keep in memory what I preached unto you, unless ye have believed in vain.
3 For I delivered unto you first of all that which I also received, how that Christ died for our sins according to the scriptures;
4 and that he was buried, and that he rose again the third day according to the scriptures:

Hebrews 6 Authorized (King James) Version (AKJV)
1 Therefore leaving the principles of the doctrine of Christ, let us go on unto perfection; not laying again the foundation of repentance from dead works, and of faith toward God,
2 of the doctrine of baptisms, and of laying on of hands, and of resurrection of the dead, and of eternal judgment.
3 And this will we do, if God permit.
4 For it is impossible for those who were once enlightened, and have tasted of the heavenly gift, and were made partakers of the Holy Ghost,
5 and have tasted the good word of God, and the powers of the world to come,
6 if they shall fall away, to renew them again unto repentance; seeing they crucify to themselves the Son of God afresh, and put him to an open shame.
7 For the earth which drinketh in the rain that cometh oft upon it, and bringeth forth herbs meet for them by whom it is dressed, receiveth blessing from God:
8 but that which beareth thorns and briers is rejected, and is nigh unto cursing; whose end is to be burned.

 

Vaccine News – Study – Thimerosal neurotoxicity is associated with glutathione depletion: protection with glutathione precursors & VAXXED TV – Vaxxed versus unvaccinated in my family

A study conducted by the Department of Paediatrics at the University of Arkansas determined that thimerosal-induced cytotoxicity was associated with the depletion of intracellular glutathione (GSH) in both cell lines. The study outlines how many vaccines have been neurotoxic, especially to the developing brain. Depletion of GSH is commonly associated with autism. Although thimerosal has been removed from most children’s vaccines, it is still present in flu vaccines given to pregnant women, the elderly and to children in developing countries.

US National Library of Medicine
National Institutes of Health – 2005

Study – Thimerosal neurotoxicity is associated with glutathione depletion: protection with glutathione precursors.

James SJ, Slikker W 3rd, Melnyk S, New E, Pogribna M, Jernigan S.
Author information
Department of Pediatrics, University of Arkansas for Medical Sciences and Arkansas Children’s Hospital Research Institute, Little Rock, AR 72202, USA. jamesjill@uams.edu

Abstract
Thimerosol is an antiseptic containing 49.5% ethyl mercury that has been used for years as a preservative in many infant vaccines and in flu vaccines. Environmental methyl mercury has been shown to be highly neurotoxic, especially to the developing brain. Because mercury has a high affinity for thiol (sulfhydryl (-SH)) groups, the thiol-containing antioxidant, glutathione (GSH), provides the major intracellular defense against mercury-induced neurotoxicity. Cultured neuroblastoma cells were found to have lower levels of GSH and increased sensitivity to thimerosol toxicity compared to glioblastoma cells that have higher basal levels of intracellular GSH. Thimerosal-induced cytotoxicity was associated with depletion of intracellular GSH in both cell lines. Pretreatment with 100 microM glutathione ethyl ester or N-acetylcysteine (NAC), but not methionine, resulted in a significant increase in intracellular GSH in both cell types. Further, pretreatment of the cells with glutathione ethyl ester or NAC prevented cytotoxicity with exposure to 15 microM Thimerosal. Although Thimerosal has been recently removed from most children’s vaccines, it is still present in flu vaccines given to pregnant women, the elderly, and to children in developing countries. The potential protective effect of GSH or NAC against mercury toxicity warrants further research as possible adjunct therapy to individuals still receiving Thimerosal-containing vaccinations.

A study conducted by the University of Texas Health Science Centre by the Department of Family and Community Medicine determined that for each 1,000 Ib of environmentally released mercury, there was a 43% increase in the rate of special education services and a 61% increase in the rate of autism. Researchers emphasized that further research was needed regarding the association between environmentally released mercury and developmental disorders such as autism.

US National Library of Medicine
National Institutes of Health – 2006

Study – Environmental mercury release, special education rates, and autism disorder: an ecological study of Texas

Palmer RF, Blanchard S, Stein Z, Mandell D, Miller C.
Author information
University of Texas Health Science Center, San Antonio Department of Family and Community Medicine, 7703 Floyd Curl Drive, San Antonio, Texas 78229-3900, USA. palmer@uthscsa.edu

Abstract
The association between environmentally released mercury, special education and autism rates in Texas was investigated using data from the Texas Education Department and the United States Environmental Protection Agency. A Poisson regression analysis adjusted for school district population size, economic and demographic factors was used. There was a significant increase in the rates of special education students and autism rates associated with increases in environmentally released mercury. On average, for each 1,000 lb of environmentally released mercury, there was a 43% increase in the rate of special education services and a 61% increase in the rate of autism. The association between environmentally released mercury and special education rates were fully mediated by increased autism rates. This ecological study suggests the need for further research regarding the association between environmentally released mercury and developmental disorders such as autism. These results have implications for policy planning and cost analysis.

A study published in the International Journal of Toxicology determined that in light of the biological plausibility of mercury’s role in neurodevelopment disorders, the present study provides further insight into one possible mechanism by which early mercury exposures could increase the risk of autism.

US National Library of Medicine
National Institutes of Health – 2003

Study – Reduced levels of mercury in first baby haircuts of autistic children

Holmes AS, Blaxill MF, Haley BE.
Author information
SafeMinds, Cambridge, Massachusetts, USA.

Abstract
Reported rates of autism have increased sharply in the United States and the United Kingdom. One possible factor underlying these increases is increased exposure to mercury through thimerosal-containing vaccines, but vaccine exposures need to be evaluated in the context of cumulative exposures during gestation and early infancy. Differential rates of postnatal mercury elimination may explain why similar gestational and infant exposures produce variable neurological effects. First baby haircut samples were obtained from 94 children diagnosed with autism using Diagnostic and Statistical Manual of Mental Disorders, 4th edition (DSM IV) criteria and 45 age- and gender-matched controls. Information on diet, dental amalgam fillings, vaccine history, Rho D immunoglobulin administration, and autism symptom severity was collected through a maternal survey questionnaire and clinical observation. Hair mercury levels in the autistic group were 0.47 ppm versus 3.63 ppm in controls, a significant difference. The mothers in the autistic group had significantly higher levels of mercury exposure through Rho D immunoglobulin injections and amalgam fillings than control mothers. Within the autistic group, hair mercury levels varied significantly across mildly, moderately, and severely autistic children, with mean group levels of 0.79, 0.46, and 0.21 ppm, respectively. Hair mercury levels among controls were significantly correlated with the number of the mothers’ amalgam fillings and their fish consumption as well as exposure to mercury through childhood vaccines, correlations that were absent in the autistic group. Hair excretion patterns among autistic infants were significantly reduced relative to control. These data cast doubt on the efficacy of traditional hair analysis as a measure of total mercury exposure in a subset of the population. In light of the biological plausibility of mercury’s role in neurodevelopmental disorders, the present study provides further insight into one possible mechanism by which early mercury exposures could increase the risk of autism.

VAXXED TV – Vaxxed versus unvaccinated in my family

Donny’s story

I was extremely pro vaccine

MMR gave my son autism

My daughter is injured for life by the flu vaccine

I will not vaccinate my children

Doctor of infectious disease

SIDS technician

Vaxxed versus unvaccinated

5 members of my family are vaccine injured

****************************************************

How to accept Jesus Christ as your personal Saviour

Testimony by Phil Robertson from Duck Dynasty

1 Corinthians 15 Authorized (King James) Version (AKJV)
1 Moreover, brethren, I declare unto you the gospel which I preached unto you, which also ye have received, and wherein ye stand;
2 by which also ye are saved, if ye keep in memory what I preached unto you, unless ye have believed in vain.
3 For I delivered unto you first of all that which I also received, how that Christ died for our sins according to the scriptures;
4 and that he was buried, and that he rose again the third day according to the scriptures:

Hebrews 6 Authorized (King James) Version (AKJV)
1 Therefore leaving the principles of the doctrine of Christ, let us go on unto perfection; not laying again the foundation of repentance from dead works, and of faith toward God,
2 of the doctrine of baptisms, and of laying on of hands, and of resurrection of the dead, and of eternal judgment.
3 And this will we do, if God permit.
4 For it is impossible for those who were once enlightened, and have tasted of the heavenly gift, and were made partakers of the Holy Ghost,
5 and have tasted the good word of God, and the powers of the world to come,
6 if they shall fall away, to renew them again unto repentance; seeing they crucify to themselves the Son of God afresh, and put him to an open shame.
7 For the earth which drinketh in the rain that cometh oft upon it, and bringeth forth herbs meet for them by whom it is dressed, receiveth blessing from God:
8 but that which beareth thorns and briers is rejected, and is nigh unto cursing; whose end is to be burned.

 

Vaccine News – Study – Blood Levels of Mercury Are Related to Diagnosis of Autism: A Reanalysis of an Important Data Set & VAXXED TV – Vaccines gave my son autism

A study published in the Journal of Child Neurology examined the question of what is leading to the apparent increase in autism. They expressed that if there is any link between autism and mercury, it is crucial that the first reports of the question are not falsely stating that no link occurs. Researchers determined that a significant relation does exist between the blood levels of mercury and the diagnosis of an autism spectrum disorder.

Journal of Child Neurology
First Published November 1, 2007

Study – Blood Levels of Mercury Are Related to Diagnosis of Autism: A Reanalysis of an Important Data Set

M. Catherine DeSoto, PhD, Robert T. Hitlan, PhD
Department of Psychology, University of Northern Iowa, Cedar Falls, Iowa,

Abstract
The question of what is leading to the apparent increase in autism is of great importance. Like the link between aspirin and heart attack, even a small effect can have major health implications. If there is any link between autism and mercury, it is absolutely crucial that the first reports of the question are not falsely stating that no link occurs. We have reanalyzed the data set originally reported by Ip et al. in 2004 and have found that the original p value was in error and that a significant relation does exist between the blood levels of mercury and diagnosis of an autism spectrum disorder. Moreover, the hair sample analysis results offer some support for the idea that persons with autism may be less efficient and more variable at eliminating mercury from the blood.

A study published in the Journal of Child Neurology noted that autistic spectrum disorders can be associated with mitochondrial dysfunction. Researchers determined that children who have mitochondrial-related dysfunctional cellular energy metabolism might be more prone to undergo autistic regression between 18 and 30 months of age if they also have infections or immunizations at the same time.

Journal of Child Neurology
First Published February 1, 2006

Study – Developmental Regression and Mitochondrial Dysfunction in a Child With Autism
1 – Jon S. Poling, MD, PhD, 2 – Richard E. Frye, MD, PhD, 3 – John Shoffner, MD, 4 – Andrew W. Zimmerman, MD
1 – Department of Neurology and Neurosurgery Johns Hopkins Hospital Baltimore, MD
2 – Department of Neurology Boston Children’s Hospital Boston, MA
3 – Horizon Molecular Medicine Georgia State University Atlanta, GA
4 – Department of Neurology and Neurosurgery Johns Hopkins Hospital Kennedy Krieger Institute Baltimore, MD

Abstract
Autistic spectrum disorders can be associated with mitochondrial dysfunction. We present a singleton case of developmental regression and oxidative phosphorylation disorder in a 19-month-old girl. Subtle abnormalities in the serum creatine kinase level, aspartate aminotransferase, and serum bicarbonate led us to perform a muscle biopsy, which showed type I myofiber atrophy, increased lipid content, and reduced cytochrome c oxidase activity. There were marked reductions in enzymatic activities for complex I and III. Complex IV (cytochrome c oxidase) activity was near the 5% confidence level. To determine the frequency of routine laboratory abnormalities in similar patients, we performed a retrospective study including 159 patients with autism (Diagnostic and Statistical Manual of Mental Disorders-IV and Childhood Autism Rating Scale) not previously diagnosed with metabolic disorders and 94 age-matched controls with other neurologic disorders. Aspartate aminotransferase was elevated in 38% of patients with autism compared with 15% of controls (P < .0001). The serum creatine kinase level also was abnormally elevated in 22 (47%) of 47 patients with autism. These data suggest that further metabolic evaluation is indicated in autistic patients and that defects of oxidative phosphorylation might be prevalent.

A study conducted by Massachusetts General Hospital at the Centre for Morphometric Analysis by the department of Paediatric Neurology illustrates how autistic brains have a growth spurt shortly after birth and then slow in growth a few short years later. Researchers have determined that neuroinflammation appears to be present in autistic brain tissue from childhood through adulthood. The study excerpt reads:
“Oxidative stress, brain inflammation and microgliosis have been much documented in association with toxic exposures including various heavy metals. The awareness that the brain as well as medical conditions of children with autism may be conditioned by chronic biomedical abnormalities such as inflammation opens the possibility that meaningful biomedical interventions may be possible well past the window of maximal neuroplasticity in early childhood because the basis for assuming that all deficits can be attributed to fixed early developmental alterations in net”

US National Library of Medicine
National Institutes of Health – 2005

Study – Large brains in autism: the challenge of pervasive abnormality

Herbert MR.
Author information
Pediatric Neurology, Center for Morphometric Analysis, Massachusetts General Hospital, Charleston, MA 02129, USA. mherbert1@partners.org

Abstract
The most replicated finding in autism neuroanatomy-a tendency to unusually large brains-has seemed paradoxical in relation to the specificity of the abnormalities in three behavioral domains that define autism. We now know a range of things about this phenomenon, including that brains in autism have a growth spurt shortly after birth and then slow in growth a few short years afterward, that only younger but not older brains are larger in autism than in controls, that white matter contributes disproportionately to this volume increase and in a nonuniform pattern suggesting postnatal pathology, that functional connectivity among regions of autistic brains is diminished, and that neuroinflammation (including microgliosis and astrogliosis) appears to be present in autistic brain tissue from childhood through adulthood. Alongside these pervasive brain tissue and functional abnormalities, there have arisen theories of pervasive or widespread neural information processing or signal coordination abnormalities (such as weak central coherence, impaired complex processing, and underconnectivity), which are argued to underlie the specific observable behavioral features of autism. This convergence of findings and models suggests that a systems- and chronic disease-based reformulation of function and pathophysiology in autism needs to be considered, and it opens the possibility for new treatment targets.

VAXXED TV – Unvaccinated family with no cancer

Vaccines ruined my daughters life

No more vaccines for my children

My son had food allergies and autism from vaccines

Vaccines gave my son autism

Unvaccinated and healthy #vaxxed #Praybig

Vaccines have my son autism and epilepsy

Vaccines have completely destroyed my son

I’m a former pro vaccine nurse

Vaccines destroyed my family

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How to accept Jesus Christ as your personal Saviour

Testimony by Phil Robertson from Duck Dynasty

1 Corinthians 15 Authorized (King James) Version (AKJV)
1 Moreover, brethren, I declare unto you the gospel which I preached unto you, which also ye have received, and wherein ye stand;
2 by which also ye are saved, if ye keep in memory what I preached unto you, unless ye have believed in vain.
3 For I delivered unto you first of all that which I also received, how that Christ died for our sins according to the scriptures;
4 and that he was buried, and that he rose again the third day according to the scriptures:

Hebrews 6 Authorized (King James) Version (AKJV)
1 Therefore leaving the principles of the doctrine of Christ, let us go on unto perfection; not laying again the foundation of repentance from dead works, and of faith toward God,
2 of the doctrine of baptisms, and of laying on of hands, and of resurrection of the dead, and of eternal judgment.
3 And this will we do, if God permit.
4 For it is impossible for those who were once enlightened, and have tasted of the heavenly gift, and were made partakers of the Holy Ghost,
5 and have tasted the good word of God, and the powers of the world to come,
6 if they shall fall away, to renew them again unto repentance; seeing they crucify to themselves the Son of God afresh, and put him to an open shame.
7 For the earth which drinketh in the rain that cometh oft upon it, and bringeth forth herbs meet for them by whom it is dressed, receiveth blessing from God:
8 but that which beareth thorns and briers is rejected, and is nigh unto cursing; whose end is to be burned.